| Compound ID |
Compound Name |
Compound Formula |
|
CP0384912
|
N-[1-(2-pyrrolidin-1-ylethyl)benzimidazol-2-yl]-1H-indole-2-carboxamide
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|
C22H23N5O
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0399573
|
4-methylsulfanyl-N-[1-(2-pyrrolidin-1-ylethyl)benzimidazol-2-yl]-1H-pyrrole-2-carboxamide
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|
C19H23N5OS
|
1
|
| 1 |
EC50 = 255 nM
|
|
|
|
CP0398002
|
4-chloro-N-[1-[2-[(3S)-3-hydroxypyrrolidin-1-yl]ethyl]benzimidazol-2-yl]benzamide
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|
C20H21ClN4O2
|
1
|
| 1 |
EC50 = 1750 nM
|
|
|
|
CP0388643
|
3,4-dichloro-N-[1-(2-pyrrolidin-1-ylethyl)benzimidazol-2-yl]benzamide
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|
C20H20Cl2N4O
|
1
|
| 1 |
EC50 = 1800 nM
|
|
|
|
CP0448321
|
4-fluoro-N-[1-(2-pyrrolidin-1-ylethyl)benzimidazol-2-yl]benzamide
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|
C20H21FN4O
|
1
|
| 1 |
EC50 = 2400 nM
|
|
|
|
CP0387028
|
N-[1-(2-pyrrolidin-1-ylethyl)benzimidazol-2-yl]-1-benzothiophene-2-carboxamide
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|
C22H22N4OS
|
1
|
| 1 |
EC50 = 3300 nM
|
|
|
|
CP0397753
|
4-methylsulfonyl-N-[1-(2-pyrrolidin-1-ylethyl)benzimidazol-2-yl]-1H-pyrrole-2-carboxamide
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|
C19H23N5O3S
|
1
|
| 1 |
EC50 = 3800 nM
|
|
|
|
CP0418704
|
4-chloranyl-N-[1-(2-pyrrolidin-1-ylethyl)benzimidazol-2-yl]benzamide
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|
C20H21ClN4O
|
1
|
| 1 |
EC50 = 6100 nM
|
|
|
|
CP0397751
|
N-[1-(2-pyrrolidin-1-ylethyl)benzimidazol-2-yl]-1H-pyrrole-2-carboxamide
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|
C18H21N5O
|
1
|
| 1 |
EC50 = 6800 nM
|
|
|
|
CP0462187
|
3-cyano-N-[1-(2-pyrrolidin-1-ylethyl)benzimidazol-2-yl]benzamide
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|
C21H21N5O
|
1
|
| 1 |
EC50 = 7800 nM
|
|
|
|
CP0448322
|
4-methylsulfonyl-N-[3-(2-pyrrolidin-1-ylethyl)imidazo[4,5-b]pyridin-2-yl]-1H-pyrrole-2-carboxamide
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|
C18H22N6O3S
|
1
|
| 1 |
EC50 = 34500 nM
|
|
|
|
CP0326947
|
4-methyl-N-[1-(2-pyrrolidin-1-ylethyl)benzimidazol-2-yl]benzamide
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|
C21H24N4O
|
1
|
| 1 |
EC50 = 39000 nM
|
|
|
|
CP0398003
|
4-chloro-N-[3-(2-pyrrolidin-1-ylethyl)imidazo[4,5-b]pyridin-2-yl]benzamide
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|
C19H20ClN5O
|
1
|
| 1 |
EC50 = 52500 nM
|
|
|
|
CP0384911
|
ASIMADOLINE HYDROCHLORIDE
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|
C27H30N2O2
|
1
|
| 1 |
EC50 = 60000 nM
|
|
|
|
CP0429396
|
N-[1-(2-pyrrolidin-1-ylethyl)benzimidazol-2-yl]-1,3-benzothiazole-2-carboxamide
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|
C21H21N5OS
|
1
|
| 1 |
EC50 = 100000 nM
|
|
|
|
CP0497946
|
5-methyl-N-[1-(2-pyrrolidin-1-ylethyl)benzimidazol-2-yl]pyridine-2-carboxamide
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|
C20H23N5O
|
1
|
| 1 |
EC50 = 100000 nM
|
|
|
|
CP0847947
|
17-Methyl-17'-cyclopropylmethyl-3'-hydroxy-6,6',7,7'-tetradehydro-4,5 alpha : 4',5' alpha-diepoxy-6,6'-(imino)[7,7'-bimorphinan]-3,14'-diol
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|
C37H39N3O5
|
2
|
| 1 |
Ki = 0.16 nM
|
|
|
| 2 |
Ki = 40 nM
|
|
|
|
CP0072629
|
2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2R,6S,14R,15R,16R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-2-propanol
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|
C26H35NO4
|
2
|
| 1 |
Ki = 0.27 nM
|
|
|
| 2 |
Ki = 0.33 nM
|
|
|
|
CP0041449
|
C18130
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|
C40H43N3O6
|
2
|
| 1 |
Ki = 0.94 nM
|
|
|
| 2 |
Ki = 70 nM
|
|
|
|
CP0682254
|
17,17'-Bis(cyclopropylmethyl)-3-methoxy-6,6',7,7'-tetradehydro-4,5:4',5'-diepoxy-6,6'-(imino)[7,7'-bimorphinan]-14,14'-diol
Show/Hide
|
C41H45N3O6
|
2
|
| 1 |
Ki = 2.7 nM
|
|
|
| 2 |
Ki = 276 nM
|
|
|
|
CP0087234
|
(1S,2S,7S,8S,12R,20R,24R,32R)-11,33-dimethyl-19,25-dioxa-11,22,33-triazaundecacyclo[24.9.1.18,14.01,24.02,32.04,23.05,21.07,12.08,20.030,36.018,37]heptatriaconta-4(23),5(21),14(37),15,17,26,28,30(36)-octaene-2,7,17,27-tetrol
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|
C34H35N3O6
|
2
|
| 1 |
Ki = 41.7 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0758384
|
17-(cyclopropylmethyl)-17'-acetyl-6,6',7,7'-tetradehydro-4,5:4',5'-diepoxy-6,6'-imino-7,7'-bimorphinan-3,3',14,14'-tetrol
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|
C38H39N3O7
|
2
|
| 1 |
Ki = 42 nM
|
|
|
| 2 |
Ki = 102 nM
|
|
|
|
CP0858302
|
17-Methyl-17'-cyclopropylmethyl-3'-methoxy-6,6',7,7'-tetradehydro-4,5 alpha : 4',5' alpha-diepoxy-6,6'-(imino)[7,7'-bimorphinan]-3,14,14'-triol
Show/Hide
|
C38H41N3O6
|
2
|
| 1 |
Ki = 52 nM
|
|
|
| 2 |
Ki = 165 nM
|
|
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