Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT01298 , Cannabinoid receptor 1
Gene Name CNR1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P21554
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053  Protein ID: PT01298
 
Compound ID Compound Name Compound Formula
CP0463977
4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-((1-cyanopiperidin-4-yl)methyl)-1H-pyrazole-3-carboxamide
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C25H24Cl2N6O2
 1
1
IC50 = 0.34 nM
   TI
   LI
   LO
   TS
CP0498679
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-hydroxy-4-phenylpiperidine-1-carbonyl)-1H-pyrazol-4-yl)acetamide
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C29H26Cl2N4O3
 1
1
IC50 = 2.9 nM
   TI
   LI
   LO
   TS
CP0003146
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
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C22H21Cl3N4O
 1
1
IC50 = 5.1 nM
   TI
   LI
   LO
   TS
CP0463975
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(5-fluoropyridin-2-yl)-4-hydroxypiperidine-1-carbonyl)-1H-pyrazol-4-yl)acetamide
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C28H24Cl2FN5O3
 1
1
IC50 = 5.5 nM
   TI
   LI
   LO
   TS