Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
 Cell Line Info 
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT01176 , cGMP-specific 3',5'-cyclic phosphodiesterase
 Protein Info 
Gene Name PDE5A
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID O76074
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053
 Cell Line Info 
 Protein ID: PT01176
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0264367
 Compound Info 
3,7-Bis(2-hydroxyethyl)icaritin
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C25H28O8
  1
1
IC50 = 74 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0010658
 Compound Info 
5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
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C22H30N6O4S
  1
1
IC50 = 75 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0160450
 Compound Info 
5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-3-[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one
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C27H30O10
  1
1
IC50 = 160 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0354149
 Compound Info 
7-(2-Hydroxyethyl)-3-O-rhamnosylicariin
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C29H34O11
  1
1
IC50 = 360 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0460413
 Compound Info 
2-(3,4-Dihydroxy-phenyl)-3,5,7-trihydroxy-8-(3-methyl-but-2-enyl)-chromen-4-one
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C20H18O7
  1
1
IC50 = 700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0401808
 Compound Info 
5,7-Dihydroxy-2-(4-hydroxy-phenyl)-8-(3-methyl-but-2-enyl)-chromen-4-one
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C20H18O5
  1
1
IC50 = 1290 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0347682
 Compound Info 
3-hydroxy-7-o-beta-glucose-8-prenyl-4'-methoxy Chrysin
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C21H20O6
  1
1
IC50 = 2200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0262424
 Compound Info 
CHEBI:78420
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C33H40O15
  1
1
IC50 = 5900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0209727
 Compound Info 
SOPHORAFLAVANONE B
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C20H20O5
  1
1
IC50 = 16230 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0262440
 Compound Info 
3,7-dimethanesulfonyl-8-prenyl-4'-methoxy Chrysin
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C21H20O6
  1
1
IC50 = 45500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS