Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT01032 , B1 bradykinin receptor
Gene Name BDKRB1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P46663
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053  Protein ID: PT01032
 
Compound ID Compound Name Compound Formula
CP0303356
N-[(2-chlorophenyl)methyl]-2-[[3-methoxy-4-(2-methylpropoxy)phenyl]methyl-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]sulfonylamino]acetamide
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C33H43ClN4O5S
 1
1
Ki = 37 nM
   TI
   LI
   LO
   TS
CP0508213
2-[[3-chloro-4-(2-methylpropoxy)phenyl]methyl-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]sulfonylamino]-N-[(2-chlorophenyl)methyl]acetamide
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C32H40Cl2N4O4S
 1
1
Ki = 188 nM
   TI
   LI
   LO
   TS
CP0459513
N-[(2-chlorophenyl)methyl]-2-[[3-methoxy-4-(2-methylpropoxy)phenyl]methyl-[4-(piperidin-1-ylmethyl)phenyl]sulfonylamino]acetamide
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C33H42ClN3O5S
 1
1
Ki = 267 nM
   TI
   LI
   LO
   TS
CP0504226
N-[(2-chlorophenyl)methyl]-2-[[3-methoxy-4-(2-methylpropoxy)phenyl]methyl-[4-(morpholin-4-ylmethyl)phenyl]sulfonylamino]acetamide
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C32H40ClN3O6S
 1
1
Ki = 463 nM
   TI
   LI
   LO
   TS
CP0522797
N-[(2-chlorophenyl)methyl]-2-[[4-[(dimethylamino)methyl]phenyl]sulfonyl-[[3-methoxy-4-(2-methylpropoxy)phenyl]methyl]amino]acetamide
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C30H38ClN3O5S
 1
1
Ki = 497 nM
   TI
   LI
   LO
   TS