Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
 Cell Line Info 
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT01026 , Sodium-dependent noradrenaline transporter
 Protein Info 
Gene Name SLC6A2
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID P23975
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053
 Cell Line Info 
 Protein ID: PT01026
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0135457
 Compound Info 
(2S,3S)-3-(3,4-Dichloro-phenyl)-2-methoxycarbonyl-8-methyl-8-azonia-bicyclo[3.2.1]octane
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C16H19Cl2NO2
  1
1
Ki = 5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0400723
 Compound Info 
2-(3-sec-Butylimino-6-diethylamino-3H-xanthen-9-yl)-5-(5-{2-[3-(3,4-dichloro-phenyl)-2-methoxycarbonyl-8-aza-bicyclo[3.2.1]oct-8-yl]-ethylcarbamoyl}-pentylsulfamoyl)-benzenesulfonic acid anion
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C50H61Cl2N5O9S2
  2
1
Ki = 91 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 194 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393973
 Compound Info 
2-(3-sec-Butylimino-6-diethylamino-3H-xanthen-9-yl)-5-(5-{2-[3-(3,4-dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carbonyloxy]-ethylcarbamoyl}-pentylsulfamoyl)-benzenesulfonic acid anion
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C50H61Cl2N5O9S2
  1
1
Ki = 177 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0853656
 Compound Info 
[1-(3-{2-[3-(3,4-Dichloro-phenyl)-2-methoxycarbonyl-8-azabicyclo[3.2.1]oct-8-yl]-ethylcarbamoyl}-propyl)-11,11-dimethyl-2,3,4,11-tetrahydro-1H-naphtho[2,3-g]quinolin-9-ylidene]-dimethyl-ammonium perchlorate
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C42H51Cl3N4O7
  1
1
Ki = 308 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393974
 Compound Info 
2-(3-sec-Butylimino-6-diethylamino-3H-xanthen-9-yl)-5-[(4-{2-[3-(3,4-dichloro-phenyl)-2-methoxycarbonyl-8-aza-bicyclo[3.2.1]oct-8-yl]-ethylcarbamoyl}-cyclohexylmethyl)-sulfamoyl]-benzenesulfonic acid anion
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C52H63Cl2N5O9S2
  1
1
Ki = 627 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS