Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT01001 , E3 ubiquitin-protein ligase XIAP
Gene Name XIAP
Organism Homo sapiens, Human
Protein Classification Other cytosolic protein
Uniprot ID P98170
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053  Protein ID: PT01001
 
Compound ID Compound Name Compound Formula
CP0068517
(4-aminophenyl)-(3,5-dimethylpyrazol-1-yl)methanone
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C12H13N3O
 1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS
CP0393067
(3,5-dimethylpyrazol-1-yl)-(2-methylphenyl)methanone
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C13H14N2O
 1
1
IC50 = 810 nM
   TI
   LI
   LO
   TS
CP0080093
(2R)-1-(4-chloro-3,5-dimethylpyrazol-1-yl)-2-[4-(2-methylpropyl)phenyl]propan-1-one
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C18H23ClN2O
 1
1
IC50 = 1010 nM
   TI
   LI
   LO
   TS
CP0386818
(3,5-Dimethyl-pyrazol-1-yl)-pyridin-4-yl-methanone
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C11H11N3O
 1
1
IC50 = 1540 nM
   TI
   LI
   LO
   TS
CP0393064
(4-chloro-3,5-dimethylpyrazol-1-yl)-(2-methylphenyl)methanone
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C13H13ClN2O
 1
1
IC50 = 1760 nM
   TI
   LI
   LO
   TS
CP0360392
(4-chloro-3,5-dimethylpyrazol-1-yl)-pyridin-4-ylmethanone
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C11H10ClN3O
 1
1
IC50 = 3990 nM
   TI
   LI
   LO
   TS
CP0068518
(4-chloro-3,5-dimethylpyrazol-1-yl)-naphthalen-2-ylmethanone
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C16H13ClN2O
 1
1
IC50 = 4130 nM
   TI
   LI
   LO
   TS
CP0393057
(4-chlorophenyl)-[3,5-dimethyl-4-(4-methylphenoxy)pyrazol-1-yl]methanone
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C19H17ClN2O2
 1
1
IC50 = 6260 nM
   TI
   LI
   LO
   TS
CP0080092
(3,5-dimethylpyrazol-1-yl)-(3-methylphenyl)methanone
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C13H14N2O
 1
1
IC50 = 6690 nM
   TI
   LI
   LO
   TS
CP0197995
(3,5-dimethylpyrazol-1-yl)-naphthalen-2-ylmethanone
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C16H14N2O
 1
1
IC50 = 8070 nM
   TI
   LI
   LO
   TS
CP0386814
(4-chloro-3,5-dimethylpyrazol-1-yl)-(4-methylphenyl)methanone
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C13H13ClN2O
 1
1
IC50 = 8660 nM
   TI
   LI
   LO
   TS
CP0249219
(4-chlorophenyl)-(3,5-dimethylpyrazol-1-yl)methanone
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C12H11ClN2O
 1
1
IC50 = 9810 nM
   TI
   LI
   LO
   TS
CP0360394
(4-aminophenyl)-[3,5-dimethyl-4-(4-methylphenoxy)pyrazol-1-yl]methanone
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C19H19N3O2
 1
1
IC50 = 10900 nM
   TI
   LI
   LO
   TS
CP0271237
(4-chloro-3,5-dimethylpyrazol-1-yl)-(3-methylphenyl)methanone
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C13H13ClN2O
 1
1
IC50 = 11900 nM
   TI
   LI
   LO
   TS
CP0213064
4-chloro-1-[(4-chlorophenyl)carbonyl]-3,5-dimethyl-1H-pyrazole
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C12H10Cl2N2O
 1
1
IC50 = 12800 nM
   TI
   LI
   LO
   TS
CP0346103
5-methyl-2-(4-methylbenzoyl)-1H-pyrazol-3-one
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C12H12N2O2
 1
1
IC50 = 14100 nM
   TI
   LI
   LO
   TS
CP0080094
2-(4-aminobenzoyl)-5-methyl-1H-pyrazol-3-one
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C11H11N3O2
 1
1
IC50 = 15900 nM
   TI
   LI
   LO
   TS
CP0392815
3,5-dimethyl-4-naphthalen-2-yloxy-1H-pyrazole
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C15H14N2O
 1
1
IC50 = 21900 nM
   TI
   LI
   LO
   TS
CP0360393
(E)-1-(4-chloro-3,5-dimethylpyrazol-1-yl)-3-phenylprop-2-en-1-one
   Show/Hide
C14H13ClN2O
 1
1
IC50 = 22300 nM
   TI
   LI
   LO
   TS
CP0248022
(4-aminophenyl)-(4-chloro-3,5-dimethylpyrazol-1-yl)methanone
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C12H12ClN3O
 1
1
IC50 = 27300 nM
   TI
   LI
   LO
   TS
CP0036918
(2S)-2-amino-3-phenylpropanoic acid
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C9H11NO2
 1
1
IC50 = 80200 nM
   TI
   LI
   LO
   TS