Brief Information of the Cell Line and Protein
Cell Line ID: CL000050 , HEK293-A
Synonyms
HEK-293A
HEK293A
HEK 293A
293A
QBI-HEK 293A
QBI-293A
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_6910
Protein ID: PT03119 , Cytochrome P450 11B1, mitochondrial
Gene Name CYP11B1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P15538
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000050  Protein ID: PT03119
 
Compound ID Compound Name Compound Formula
CP0474326
[4-(4-fluorophenyl)sulfanylpyrimidin-5-yl]-(1-methylsulfonylpiperidin-4-yl)methanol
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C17H20FN3O3S2
 1
1
IC50 = 0.6 nM
   TI
   LI
   LO
   TS
CP0474328
1-[4-(4-fluoroanilino)pyrimidin-5-yl]-1-(1-methylsulfonylpiperidin-4-yl)ethanol
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C18H23FN4O3S
 1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
CP0118782
[4-(4-fluoroanilino)pyrimidin-5-yl]-(1-methylsulfonylpiperidin-4-yl)methanol
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C17H21FN4O3S
 1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CP0393816
4-[[5-[hydroxy-(1-methylsulfonylpiperidin-4-yl)methyl]pyrimidin-4-yl]amino]benzonitrile
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C18H21N5O3S
 1
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
CP0393706
[4-(3-fluoroanilino)pyrimidin-5-yl]-(1-methylsulfonylpiperidin-4-yl)methanol
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C17H21FN4O3S
 1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
CP0393814
1-[4-(4-fluoroanilino)pyrimidin-5-yl]-2-methyl-1-(1-methylsulfonylpiperidin-4-yl)propan-1-ol
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C20H27FN4O3S
 1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
CP0519419
(1-methylsulfonylpiperidin-4-yl)-[4-[4-(trifluoromethyl)anilino]pyrimidin-5-yl]methanol
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C18H21F3N4O3S
 1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
CP0474327
[4-(4-methylanilino)pyrimidin-5-yl]-(1-methylsulfonylpiperidin-4-yl)methanol
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C18H24N4O3S
 1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
CP0393707
(4-anilinopyrimidin-5-yl)-(1-methylsulfonylpiperidin-4-yl)methanol
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C17H22N4O3S
 1
1
IC50 = 42 nM
   TI
   LI
   LO
   TS
CP0412919
[4-(4-fluoroanilino)pyrimidin-5-yl]-phenylmethanol
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C17H14FN3O
 1
1
IC50 = 93 nM
   TI
   LI
   LO
   TS
CP0405614
(1-methylsulfonylpiperidin-4-yl)-[4-(naphthalen-1-ylamino)pyrimidin-5-yl]methanol
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C21H24N4O3S
 1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CP0519418
1-[4-(4-fluoroanilino)pyrimidin-5-yl]-1-(1-methylsulfonylpiperidin-4-yl)pentan-1-ol
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C21H29FN4O3S
 1
1
IC50 = 124 nM
   TI
   LI
   LO
   TS
CP0547401
1-[4-(4-fluoroanilino)pyrimidin-5-yl]butan-1-ol
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C14H16FN3O
 1
1
IC50 = 181 nM
   TI
   LI
   LO
   TS