Brief Information of the Cell Line and Protein
Cell Line ID: CL000047 , 108CC15
 Cell Line Info 
Synonyms
NG108-15
NG-108-15
NG 108-15
NG10815
Category Hybrid cell line
Organism
Mus musculus (Mouse)--NCBI_TaxID=10116;
Cellosaurus ID
CVCL_0464
Protein ID: PT01713 , Muscarinic acetylcholine receptor M3
 Protein Info 
Gene Name CHRM3
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P08483
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000047
 Cell Line Info 
 Protein ID: PT01713
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0279976
 Compound Info 
N-methyl-N-(5-pyrrolidin-1-ylpent-3-yn-2-yl)acetamide
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C12H20N2O
  1
1
Ki = 580 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0848705
 Compound Info 
8-Amino-octanoic acid methyl-(4-pyrrolidin-1-yl-but-2-ynyl)-amide: (2 TFA)
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C21H33F6N3O5
  1
1
Ki = 700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0885425
 Compound Info 
{7-[Methyl-(4-pyrrolidin-1-yl-but-2-ynyl)-carbamoyl]-heptyl}-carbamic acid tert-butyl ester: (0.25 oxalate)
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C24H41N3O7
  1
1
Ki = 1900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0848884
 Compound Info 
7-Amino-heptanoic acid methyl-(4-pyrrolidin-1-yl-but-2-ynyl)-amide: (2 TFA)
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C20H31F6N3O5
  1
1
Ki = 3100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0894016
 Compound Info 
{6-[Methyl-(4-pyrrolidin-1-yl-but-2-ynyl)-carbamoyl]-hexyl}-carbamic acid tert-butyl ester: (0.5 oxalate)
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C23H39N3O7
  1
1
Ki = 3200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0399506
 Compound Info 
N-methyl-N-(4-pyrrolidin-1-ylbut-2-ynyl)acetamide
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C11H18N2O
  1
1
Ki = 4500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS