Brief Information of the Cell Line and Protein
Cell Line ID: CL000045 , A-375
Synonyms
A 375
A375
A375-MEL
A375-mel
A375mel
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0132
Protein ID: PT03251 , Serine/threonine-protein kinase A-Raf
Gene Name ARAF
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P10398
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000045  Protein ID: PT03251
 
Compound ID Compound Name Compound Formula
CP0095082
DABRAFENIB
   Show/Hide
C23H20F3N5O2S2
 1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
CP0672877
1-(3,3-Dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea
   Show/Hide
C23H29FN6O
 1
1
IC50 = 44 nM
   TI
   LI
   LO
   TS
CP0006321
PLX-4032
   Show/Hide
C23H18ClF2N3O3S
 1
1
IC50 = 950 nM
   TI
   LI
   LO
   TS