Brief Information of the Cell Line and Protein
Cell Line ID: CL000045 , A-375
Synonyms
A 375
A375
A375-MEL
A375-mel
A375mel
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0132
Protein ID: PT02223 , Protein arginine N-methyltransferase 6
Gene Name PRMT6
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID Q96LA8
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000045  Protein ID: PT02223
 
Compound ID Compound Name Compound Formula
CP0849394
(trans)-N1,N2-dimethyl-N1-((3-(4-(3-(2-(tetrahydro-2H-pyran-4-yl)ethoxy)cyclobutoxy)phenyl)-1H-pyrazol-4-yl)methyl)ethane-1,2-diamine
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C25H38N4O3
 1
1
IC50 = 637 nM
   TI
   LI
   LO
   TS
CP0873454
4-methyl-2-(3-(4-((methyl(2-(methylamino)ethyl)amino)methyl)-1H-pyrazol-5-yl)-5-(trifluoromethyl)phenoxy)pentan-1-ol
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C21H31F3N4O2
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS