Brief Information of the Cell Line and Protein
Cell Line ID: CL000044 , CV-1
Synonyms
Cv-1
CV 1
CV-1.K
CV1
Category Finite cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0229
Protein ID: PT06268 , Hepatocyte nuclear factor 4-alpha
Gene Name HNF4A
Organism Rattus norvegicus, Rat
Protein Classification Unclassified protein
Uniprot ID P22449
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000044  Protein ID: PT06268
 
Compound ID Compound Name Compound Formula
CP0825655
4-(3-ethoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)benzoic acid
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C24H28O4
 1
1
EC50 = 263 nM
   TI
   LI
   LO
   TS
CP0662712
(rel)-methyl 4-((4aS,5S,10bS)-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-5-yl)benzoate
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C20H21NO3
 1
1
EC50 = 426 nM
   TI
   LI
   LO
   TS
CP0848963
4-(3-(2,2-difluoroethoxy)-5,5,8,8-tetramethyl-4-nitro-5,6,7,8-tetrahydronaphthalene-2-carbonyl)benzoic acid
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C24H25F2NO6
 1
1
EC50 = 594 nM
   TI
   LI
   LO
   TS
CP0850478
(rel)-2-(4-((4aS,5S,10bS)-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-5-yl)phenyl)acetic acid
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C20H21NO3
 1
1
EC50 = 649 nM
   TI
   LI
   LO
   TS
CP0954212
(rel)-4-((3aS,11cS)-2,3,3a,4,5,11c-hexahydrobenzo[f]furo[3,2-c]quinolin-4-yl)benzoic acid
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C22H19NO3
 1
1
EC50 = 778 nM
   TI
   LI
   LO
   TS
CP0825654
2-(4-(3-ethoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)phenyl)-2-oxoacetic acid
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C25H28O5
 1
1
EC50 = 1142 nM
   TI
   LI
   LO
   TS
CP0658706
(rel)-4-((4aS,5S,10bS)-8,9-dimethyl-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-5-yl)benzoic acid
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C21H23NO3
 1
1
EC50 = 1728 nM
   TI
   LI
   LO
   TS
CP0662713
4-(5,5,8,8-tetramethyl-3-(2,2,2-trifluoroethoxy)-5,6,7,8-tetrahydronaphthalene-2-carbonyl)benzoic acid
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C24H25F3O4
 1
1
EC50 = 2194 nM
   TI
   LI
   LO
   TS
CP0658708
4-(3,5,5,8,8-pentamethyl-4-nitro-5,6,7,8-tetrahydronaphthalene-2-carbonyl)benzoic acid
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C23H25NO5
 1
1
EC50 = 2234 nM
   TI
   LI
   LO
   TS
CP0679310
4-(7-ethoxy-4,4-dimethylchroman-6-carbonyl)benzoic acid
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C21H22O5
 1
1
EC50 = 2237 nM
   TI
   LI
   LO
   TS
CP0679281
4-(1-hydroxy-3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)benzoic acid
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C23H26O4
 1
1
EC50 = 2645 nM
   TI
   LI
   LO
   TS
CP0843617
4-(7-methoxy-1,4,4,8-tetramethyl-1,2,3,4-tetrahydroquinoline-6-carbonyl)benzoic acid
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C22H25NO4
 1
1
EC50 = 2848 nM
   TI
   LI
   LO
   TS
CP0843618
4-(4,4,7-trimethyl-8-nitrochroman-6-carbonyl)benzoic acid
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C20H19NO6
 1
1
EC50 = 2948 nM
   TI
   LI
   LO
   TS
CP0658707
4-((2-(2,5-difluorophenyl)hydrazono)(3-ethoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)methyl)benzoic acid
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C30H32F2N2O3
 1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CP0747814
4-((3-ethoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)(hexyloxyimino)methyl)benzoic acid
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C30H41NO4
 1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CP0853129
4-((3-ethoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)(isopentyloxyimino)methyl)benzoic acid
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C29H39NO4
 1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
CP0663302
4-[(5,6,7,5-tetrahydro-5,5,5,5-tetramethyl-3-ethoxy-2-naphthalenyl)(butyloxy)methyl]benzoic acid
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C28H38O4
 1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
CP0679309
4-[(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)(2-fluorobenzyloxy)methyl]benzoic acid
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C30H33FO3
 1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
CP0778823
4-((2-(2,5-dimethylphenyl)hydrazono)(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)methyl)benzoic acid
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C31H36N2O2
 1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
CP0679282
4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-methyl-4-p-tolenesulfonamido-2-naphthalenyl)methyl]benzoic acid
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C30H35NO4S
 1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
CP0658711
4-((2,3-difluorobenzyloxyimino)(3-ethoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)methyl)benzoic acid
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C31H33F2NO4
 1
1
IC50 = 35 nM
   TI
   LI
   LO
   TS
CP0658710
4-((2-phenylhydrazono)(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)methyl)benzoic acid
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C28H30N2O2
 1
1
IC50 = 103 nM
   TI
   LI
   LO
   TS
CP0848956
(rel)-4-((4aS,12cS)-3,4,4a,5,6,12c-hexahydro-2H-benzo[f]pyrano[3,2-c]quinolin-5-yl)benzoic acid
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C23H21NO3
 1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS