WAY-362450

Azepino[4,5-b]indole, 6l

Azepino[4,5-b]indole, 6i

6-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-4-(ethyloxy)-2-quinolinecarboxylic acid

6-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-4-[(1-methylethyl)oxy]-2-quinolinecarboxylic acid

6-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-4-(methyloxy)-2-quinolinecarboxylic acid

3-[(E)-2-[2-chloro-4-[[2-(2,6-dichlorophenyl)-4-propan-2-ylpyrazol-3-yl]methoxy]phenyl]ethenyl]benzoic acid

Azepino[4,5-b]indole, 6h

6-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-4-(propyloxy)-2-quinolinecarboxylic acid

6-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-4-methyl-2-quinolinecarboxylic acid

6-[4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]-1-benzothiophene-3-carboxylic acid

Azepino[4,5-b]indole, 6j

Azepino[4,5-b]indole, 6k

6-[4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]-1H-indole-3-carboxylic acid

Azepino[4,5-b]indole, 6g

3-[5-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-1-benzothien-2-yl]benzoic acid

6-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-4-ethyl-2-quinolinecarboxylic acid

3-[(E)-2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yltriazol-4-yl]methoxy]phenyl]ethenyl]benzoic acid

3-[(E)-2-[2-chloro-4-[[3-[2-(2,6-dichlorophenyl)ethyl]-2-oxo-5-propan-2-yl-1,3-oxazol-4-yl]methoxy]phenyl]ethenyl]benzoic acid

6-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-3-methyl-2-quinolinecarboxylic acid

6-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-3-methylphenyl]-2-quinolinecarboxylic acid

Naphthoic acid-based analog, 1c

3-(2-chloro-4-((3-(2,6-dichlorophenethyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

6-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-2-quinolinecarboxylic acid

3-aryl isoxazole analog, 6d

6-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-2-methylphenyl]-2-quinolinecarboxylic acid

3-[(E)-2-[2-chloro-4-[[3-[(2,6-dichlorophenyl)methyl]-2-oxo-5-propan-2-yl-1,3-oxazol-4-yl]methoxy]phenyl]ethenyl]benzoic acid

3-(2-chloro-4-((3-((2,6-dimethylphenoxy)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

Azepino[4,5-b]indole, 6d

Azepino[4,5-b]indole, 6f

3-(6-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}-1-benzothiophen-2-yl)benzoic acid

3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid

Naphthoic acid-based analog, 1b

3-(2-chloro-4-((3-((2,6-dichlorophenylsulfinyl)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

Azepino[4,5-b]indole, 6e

7-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-3-isoquinolinecarboxylic acid

3-{[6-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-1-naphthalenyl]amino}benzoic acid

6-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-4-[(2-methylpropyl)oxy]-2-quinolinecarboxylic acid

3-(2-chloro-4-((3-((2,6-dichlorophenoxy)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

(R)-3-(4-((5-sec-butyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-chlorostyryl)benzoic acid

3-(2-chloro-4-((5-isopropyl-3-phenethylisoxazol-4-yl)methoxy)styryl)benzoic acid

3-(2-chloro-4-((3-((2,6-dichlorophenylthio)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

3-(2-chloro-4-((3-((4-chloro-2,6-dimethylphenoxy)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

6-[4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]-7-fluoroquinoline-2-carboxylic acid

5-[4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]-1H-indole-2-carboxylic acid

3-(6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)naphthalen-2-yl)benzoic acid

5-[4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]-1-benzofuran-2-carboxylic acid

3-(2-chloro-4-((5-cyclobutyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)styryl)benzoic acid

3-(2-chloro-4-((3-((2,6-dichlorophenylamino)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

6-[4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]-1H-indole-2-carboxylic acid

3-[(E)-2-[2-chloro-4-[[5-(2,6-dichlorophenyl)-3-propan-2-yltriazol-4-yl]methoxy]phenyl]ethenyl]benzoic acid

3-(2-chloro-4-((3-((2-chloro-6-methylphenoxy)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

4-[5-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-1-benzothien-2-yl]benzoic acid

6-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-1-isoquinolinecarboxylic acid

3-(2-chloro-4-((5-isopropyl-3-((2,4,6-trichlorophenoxy)methyl)isoxazol-4-yl)methoxy)styryl)benzoic acid

3-[(5-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}-1H-indol-1-yl)methyl]benzoic acid

4-[6-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-1-benzothien-2-yl]benzoic acid

3-(4-((3-benzyl-5-isopropylisoxazol-4-yl)methoxy)-2-chlorostyryl)benzoic acid

3-(2-chloro-4-((5-cyclopentyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)styryl)benzoic acid

7-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-3-quinolinecarboxylic acid

(S)-3-(4-((5-sec-butyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-chlorostyryl)benzoic acid

3-(2-chloro-4-((3-((2-chloro-6-fluorophenoxy)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

3-(2-chloro-4-((5-isopropyl-3-((2,4,6-trifluorophenoxy)methyl)isoxazol-4-yl)methoxy)styryl)benzoic acid

4-{[5-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-1H-indol-1-yl]methyl}benzoic acid

3-[2-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}amino)-1,3-benzothiazol-6-yl]benzoic acid

3-(2-chloro-4-((3-((2,6-dichlorophenylsulfonyl)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

3-[6-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-1,3-benzothiazol-2-yl]benzoic acid

3-(2-chloro-4-((3-((3,5-dichloropyridin-4-ylamino)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

5-[4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]-2,3-dihydro-1H-indene-2-carboxylic acid

Azepino[4,5-b]indole, 6a

Azepino[4,5-b]indole, 6b

Naphthoic acid-based analog, 1d

1-[[4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]methyl]indole-6-carboxylic acid

5-[4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]-1-benzothiophene-2-carboxylic acid

7-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-4-quinolinecarboxylic acid

3-[(E)-2-[2-chloro-4-[[5-[(2,6-dichlorophenoxy)methyl]-3-propan-2-ylimidazol-4-yl]methoxy]phenyl]ethenyl]benzoic acid

3-(4-((3-(tert-butoxymethyl)-5-isopropylisoxazol-4-yl)methoxy)-2-chlorostyryl)benzoic acid

Azepino[4,5-b]indole, 1

3-(2-chloro-4-((3-((2,3-dichlorophenoxy)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

3-[5-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-1H-indol-2-yl]benzoic acid

3-[(E)-2-[2-chloro-4-[[3-[2-(2,6-dichlorophenyl)ethyl]-5-propan-2-ylimidazol-4-yl]methoxy]phenyl]ethenyl]benzoic acid

3-(2-chloro-4-((3-((2,4-dichlorophenoxy)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

6-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-2-quinoxalinecarboxylic acid

3-(2-{2-[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]ethyl}-1,3-benzoxazol-5-yl)benzoic acid

3-(2-chloro-4-((3-((2,6-difluorophenoxy)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

6-[4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid

3-{[5-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazoly]methyl}oxy)-1H-indol-1-yl]carbonyl}benzoic acid

3-(2-chloro-4-((3-((2,5-dichlorophenoxy)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

3-{[5-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-1H-indol-3-yl]methyl}benzoic acid

4-[6-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-2-naphthalenyl]benzoic acid

4-[4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]sulfanyl-1-benzothiophene-2-carboxylic acid

6-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-4-methyl-2-quinazolinecarboxylic acid

Azepino[4,5-b]indole, 6c

3-[5-({[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]benzoic acid

3-(2-chloro-4-((5-isopropyl-3-(phenoxymethyl)isoxazol-4-yl)methoxy)styryl)benzoic acid

3-(2-chloro-4-((5-isopropyl-3-((naphthalen-1-yloxy)methyl)isoxazol-4-yl)methoxy)styryl)benzoic acid

3-(2-chloro-4-((5-isopropyl-3-(3-phenylpropyl)isoxazol-4-yl)methoxy)styryl)benzoic acid

3-(2-chloro-4-((3-((4-chlorophenoxy)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

3-{[5-({[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-1H-indol-1-yl]sulfonyl}benzoic acid

2-[4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]-1H-benzimidazole-4-carboxylic acid

5-[4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]thieno[3,2-b]pyridine-2-carboxylic acid

3-(2-chloro-4-((3-(2,6-dichlorophenyl)-5-(1-methyl-1H-tetrazol-5-yl)isoxazol-4-yl)methoxy)styryl)benzoic acid

3-(2-chloro-4-((5-isopropyl-3-((naphthalen-2-yloxy)methyl)isoxazol-4-yl)methoxy)styryl)benzoic acid

Naphthoic acid-based analog, 1e

3-{[5-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-1H-benzimidazol-1-yl]methyl}benzoic acid

3-[6-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-1-oxo-3,4-dihydro-2(1H)-isoquinolinyl]benzoic acid

3-(2-chloro-4-((3-(hydroxymethyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

3-[6-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)-3-oxo-3,4-dihydro-2(1H)-isoquinolinyl]benzoic acid

3-[(2-{2-[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]ethyl}-1,3-benzoxazol-7-yl)amino]benzoic acid

3-[[5-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]-1H-indol-3-yl]methyl]benzoic acid

6-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-4-hydroxy-2-quinolinecarboxylic acid

7-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-1,2,4-benzotriazine-3-carboxylic acid

3-[(E)-2-[2-chloro-4-[[4-[(2,6-dichlorophenoxy)methyl]-2-propan-2-ylfuran-3-yl]methoxy]phenyl]ethenyl]benzoic acid

(2R)-2-[(E)-5-[(2S)-6-hydroxy-2,8-dimethylchromen-2-yl]-2-methylpent-2-enyl]-4-(4-methylpent-3-enyl)-2H-furan-5-one

12-O-deacetyl-12-epi-19-deoxy-21-hydroxyscalarin

2'-epi-Tuberatolide B

(2R)-2-[(E)-2-methyl-6-oxohept-2-enyl]-4-(4-methylpent-3-enyl)-2H-furan-5-one

(E)-guggulsterone

yezoquinolide

[(1R,5bS,11aS,13R,13aS,13bS)-13-acetyloxy-1-hydroxy-8,8,11a,13a-tetramethyl-1,3,5,5a,6,7,7a,9,10,11,11b,12,13,13b-tetradecahydrophenanthro[2,1-e][2]benzofuran-5b-yl]methyl acetate

(R)-sargachromenol

(Z)-Gugglesterone

(S)-sargachromenol

12-O-deacetyl-12-epi-19-O-methylscalarin

(1R,5bR,11aS,13R,13aS,13bS)-1-methoxy-5b,8,8,11a,13a-pentamethyl-1,3,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a,13b-octadecahydrochryseno[2,1-c]furan-13-ol

((1R,5bS,11aS,13R,13aS,13bS)-1,13-dihydroxy-8,8,11a,13a-tetramethyl-1,3,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a,13b-octadecahydrochryseno[2,1-c]furan-5b-yl)methyl acetate

(5aS,5bR,7aS,11aS,11bR,13R,13aS,13bR)-13-hydroxy-5b,8,8,11a,13a-pentamethyl-1,5,5a,6,7,7a,8,9,10,11,11a,11b,12,13,13a,13b-hexadecahydrochryseno[2,1-c]furan-3(5bH)-one

12-Episcalarin

(1R,5bS,11aS,13R,13aS,13bS)-5b-(hydroxymethyl)-8,8,11a,13a-tetramethyl-1,3,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a,13b-octadecahydrochryseno[2,1-c]furan-1,13-diol

12-O-deacetyl-12-epi-scalarin

(1R,5bR,11aS,13R,13aS,13bS)-1-hydroxy-5b,8,8,11a,13a-pentamethyl-1,3,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a,13b-octadecahydrochryseno[2,1-c]furan-13-yl acetate

12-O-deacetyl-12-epi-19-deoxy-22-hydroxyscalarin