Brief Information of the Cell Line and Protein
Cell Line ID: CL000040 , THP-1
 Cell Line Info 
Synonyms
THP1
THP 1
THPI
THP-1(ATCC)
THP-1-O
O-THP-1
Tohoku Hospital Pediatrics-1
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0006
Protein ID: PT01557 , Indoleamine 2,3-dioxygenase 1
 Protein Info 
Gene Name IDO1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P14902
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000040
 Cell Line Info 
 Protein ID: PT01557
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0470914
 Compound Info 
4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(3-methyl-1,2,4-thiadiazol-5-yl)amino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
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C26H34N4O3S
  1
1
IC50 = 4.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0081974
 Compound Info 
US10034864, Example 1
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C11H13BrFN7O4S
  1
1
IC50 = 5.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0423812
 Compound Info 
4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(4-methylphenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
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C31H39N3O4
  1
1
IC50 = 5.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0446512
 Compound Info 
4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(2-fluorophenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
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C30H36FN3O4
  1
1
IC50 = 5.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0446513
 Compound Info 
4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(5-methyl-1,3,4-thiadiazol-2-yl)amino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
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C26H34N4O3S
  1
1
IC50 = 6.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0423815
 Compound Info 
4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(4-methyl-1,3-thiazol-2-yl)amino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
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C27H35N3O3S
  1
1
IC50 = 7.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0423816
 Compound Info 
4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(4-fluorophenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
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C30H36FN3O4
  1
1
IC50 = 8.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0475300
 Compound Info 
2-[4-[bis(2-methylpropyl)amino]-3-[(4-methylphenyl)carbamoylamino]phenyl]benzoic acid
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C29H35N3O3
  1
1
IC50 = 10.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS