Brief Information of the Cell Line and Protein
Cell Line ID: CL000040 , THP-1
 Cell Line Info 
Synonyms
THP1
THP 1
THPI
THP-1(ATCC)
THP-1-O
O-THP-1
Tohoku Hospital Pediatrics-1
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0006
Protein ID: PT01327 , Sterol O-acyltransferase 1
 Protein Info 
Gene Name SOAT1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P35610
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000040
 Cell Line Info 
 Protein ID: PT01327
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0088062
 Compound Info 
2-[7-(2,2-dimethylpropanoylamino)-4,6-dimethyl-1-octyl-2,3-dihydroindol-5-yl]acetic acid
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C25H40N2O3
  2
1
IC50 = 300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 1800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0493663
 Compound Info 
N-[5-(aminomethyl)-4,6-dimethyl-1-octyl-2,3-dihydroindol-7-yl]-2,2-dimethylpropanamide
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C24H41N3O
  1
1
IC50 = 330 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0372767
 Compound Info 
N-(4,6-dimethyl-1-octyl-2,3-dihydroindol-7-yl)-2,2-dimethylpropanamide
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C23H38N2O
  1
1
IC50 = 640 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0088064
 Compound Info 
2,6-diisopropylphenyl 2-(2,4,6-triisopropylphenyl)acetylsulfamate
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C29H43NO4S
  1
1
IC50 = 1500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0524386
 Compound Info 
3-[4,6-Dimethyl-7-(2,2-dimethylpropanamido)-1-octylindolin-3-yl]propionic Acid
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C26H42N2O3
  1
1
IC50 = 3600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0374419
 Compound Info 
10-[7-(2,2-Dimethylpropanamido)-4,6-dimethylindolin-1-yl]decanoic Acid
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C25H40N2O3
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0508882
 Compound Info 
4-(4,6-Dimethyl-1-octylindolin-7-yl)carbamoyl-4-methylpentanoic Acid
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C25H40N2O3
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0511841
 Compound Info 
N-[4,6-dimethyl-1-octyl-5-(2H-tetrazol-5-ylmethyl)-2,3-dihydroindol-7-yl]-2,2-dimethylpropanamide
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C25H40N6O
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS