| Compound ID |
Compound Name |
Compound Formula |
|
CP0010680
|
4-amino-6-[[(1S)-1-(5-methyl-4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
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|
C20H18N8O
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
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CP0010681
|
4-amino-6-[[(1S)-1-[4-oxo-3-phenyl-5-(trifluoromethyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
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|
C20H15F3N8O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0011858
|
4-amino-6-[[(1S)-1-(5-fluoro-4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
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|
C19H15FN8O
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0005403
|
4-amino-6-[[(1S)-1-(4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
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|
C19H16N8O
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0007182
|
2-[(1S)-1-[(2-amino-7H-purin-6-yl)amino]ethyl]-3-phenylpyrrolo[2,1-f][1,2,4]triazin-4-one
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|
C19H17N9O
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0009440
|
4-amino-6-[(2S)-2-(4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl)pyrrolidin-1-yl]pyrimidine-5-carbonitrile
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|
C21H18N8O
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0002077
|
3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)ethyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
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|
C19H16N8O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0003657
|
2-[(1S)-1-[(6-amino-5-cyanopyrimidin-4-yl)amino]ethyl]-4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazine-5-carbonitrile
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|
C20H15N9O
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0007188
|
4-amino-6-[[(1S)-1-(7-methyl-4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
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|
C20H18N8O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0011200
|
2-[(1S)-1-[(6-amino-5-cyanopyrimidin-4-yl)amino]ethyl]-4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazine-7-carbonitrile
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|
C20H15N9O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0014345
|
4-amino-6-[[(1S)-3-hydroxy-1-(4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl)propyl]amino]pyrimidine-5-carbonitrile
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|
C20H18N8O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0006811
|
4-amino-6-[[(1S)-1-(4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl)propyl]amino]pyrimidine-5-carbonitrile
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|
C20H18N8O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0006806
|
4-amino-6-[[(1S)-1-[5-(hydroxymethyl)-4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
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|
C20H18N8O2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0014344
|
2-[(1S)-1-[(5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]ethyl]-3-phenylpyrrolo[2,1-f][1,2,4]triazin-4-one
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|
C20H16FN7O
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0005405
|
4-amino-6-[[(1R)-2-hydroxy-1-(4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
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|
C19H16N8O2
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0635683
|
(S)-4-Amino-6-(1-(6-fluoro-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethylamino)pyrimidine-5-carbonitrile
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|
C19H15FN8O
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0002079
|
2-[(1S)-1-[(4,6-diamino-1,3,5-triazin-2-yl)amino]ethyl]-3-phenylpyrrolo[2,1-f][1,2,4]triazin-4-one
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|
C17H17N9O
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
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CP0005402
|
3-phenyl-2-[(1S)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)ethyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
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|
C20H17N7O
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
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CP0002078
|
2-[(1S)-1-[(6-amino-5-fluoropyrimidin-4-yl)amino]ethyl]-3-phenylpyrrolo[2,1-f][1,2,4]triazin-4-one
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|
C18H16FN7O
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
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CP0011201
|
4-amino-6-[[(1S)-1-(4-oxo-3-phenylimidazo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
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|
C18H15N9O
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
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CP0005406
|
4-amino-6-[(2S)-4,4-difluoro-2-(4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl)pyrrolidin-1-yl]pyrimidine-5-carbonitrile
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|
C21H16F2N8O
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0009441
|
4-amino-6-[[(1S)-1-[4-oxo-3-phenyl-7-(trifluoromethyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
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|
C20H15F3N8O
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0007192
|
4-amino-6-[[3,3,3-trifluoro-1-(4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl)propyl]amino]pyrimidine-5-carbonitrile
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|
C20H15F3N8O
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
