Brief Information of the Cell Line and Protein
Cell Line ID: CL000040 , THP-1
 Cell Line Info 
Synonyms
THP1
THP 1
THPI
THP-1(ATCC)
THP-1-O
O-THP-1
Tohoku Hospital Pediatrics-1
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0006
Protein ID: PT00877 , Inhibitor of nuclear factor kappa-B kinase subunit beta
 Protein Info 
Gene Name IKBKB
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID O14920
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000040
 Cell Line Info 
 Protein ID: PT00877
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0160132
 Compound Info 
N,12-dimethyl-11,14,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,15}]heptadeca-1,3,5,7,9,12,14,16-octaen-16-amine
   Show/Hide
C16H14N4
  1
1
IC50 = 340 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0133399
 Compound Info 
12-methyl-N-[2-(piperidin-1-yl)ethyl]-11,14,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,15}]heptadeca-1,3,5,7,9,12,14,16-octaen-16-amine
   Show/Hide
C22H25N5
  1
1
IC50 = 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0160152
 Compound Info 
N,12-dimethyl-12,14,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,15}]heptadeca-1,3,5,7,9,11(15),13,16-octaen-16-amine
   Show/Hide
C16H14N4
  1
1
IC50 = 950 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0709611
 Compound Info 
N-methyl-N'-(1-methyl-3,5,11b-triaza-cyclopenta[a]anthracen-4-yl)-ethane-1,2-diamine hydrochloride
   Show/Hide
C18H20ClN5
  1
1
IC50 = 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0224246
 Compound Info 
2-({12-methyl-11,14,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,15}]heptadeca-1,3,5,7,9,12,14,16-octaen-16-yl}amino)ethan-1-ol
   Show/Hide
C17H16N4O
  1
1
IC50 = 1400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0210251
 Compound Info 
benzopyrazoloquinazoline analogue, 13b
   Show/Hide
C18H19N5
  1
1
IC50 = 1500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0709373
 Compound Info 
N1-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine hydrochloride
   Show/Hide
C14H18ClN5
  1
1
IC50 = 4000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0210250
 Compound Info 
N-(2-aminoethyl)-12-methyl-12,14,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,15}]heptadeca-1,3,5,7,9,11(15),13,16-octaen-16-amine
   Show/Hide
C17H17N5
  1
1
IC50 = 5900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0210238
 Compound Info 
N,12-dimethyl-14,15,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,15}]heptadeca-1,3,5,7,9,11,13,16-octaen-16-amine
   Show/Hide
C16H14N4
  1
1
IC50 = 8300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS