Brief Information of the Compound and Protein
Compound Name
N,12-dimethyl-11,14,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,15}]heptadeca-1,3,5,7,9,12,14,16-octaen-16-amine
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PubChem ID
CID: 16663529
SID: 26523507
Canonical SMILES
CNc1nc2cc3ccccc3cc2n2c(C)cnc12
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Compound Formula C16H14N4
Compound Structure
Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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Other protein kinase group
Uniprot ID
O14920
Gene Name
IKBKB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 340 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 18 nM
2 IC50 = 18.2 nM