Compound ID |
Compound Name |
Compound Formula |
CP0384973
|
4-(2-methyl-4-(6-(pyrrolidin-1-yl)pyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)-N-neopentylbenzamide
Show/Hide
|
C30H34N6O2
|
1
|
1 |
IC50 < 10 nM
|
|
|
CP0435599
|
3,3-dimethyl-1-(4-(2-methyl-4-(6-morpholinopyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)piperidin-1-yl)butan-1-one
Show/Hide
|
C29H38N6O3
|
1
|
1 |
IC50 < 10 nM
|
|
|
CP0490486
|
1-(4-(4-(6-(dimethylamino)pyrido[3,4-d]pyrimidin-4-ylamino)-2-methylphenoxy)piperidin-1-yl)-3,3-dimethylbutan-1-one
Show/Hide
|
C27H36N6O2
|
1
|
1 |
IC50 < 10 nM
|
|
|
CP0542302
|
4-(4-(6-(dimethylamino)pyrido[3,4-d]pyrimidin-4-ylamino)-2-methylphenoxy)-N-neopentylbenzamide
Show/Hide
|
C28H32N6O2
|
1
|
1 |
IC50 < 10 nM
|
|
|
CP0406560
|
4-(2-methyl-4-(6-(methylamino)pyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)-N-neopentylbenzamide
Show/Hide
|
C27H30N6O2
|
1
|
1 |
IC50 = 13 nM
|
|
|
CP0486204
|
4-(2-methyl-4-(6-(4-methylpiperazin-1-yl)pyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)-N-neopentylbenzamide
Show/Hide
|
C31H37N7O2
|
1
|
1 |
IC50 = 15 nM
|
|
|
CP0529746
|
4-(2-methyl-4-(6-(2-morpholinoethylamino)pyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)-N-neopentylbenzamide
Show/Hide
|
C32H39N7O3
|
1
|
1 |
IC50 = 15 nM
|
|
|
CP0406563
|
N-[3-[4-[4-[1-(3,3-dimethylbutanoyl)piperidin-4-yl]oxy-3-methylanilino]quinazolin-6-yl]prop-2-ynyl]-2-methoxyacetamide
Show/Hide
|
C32H39N5O4
|
1
|
1 |
IC50 = 16 nM
|
|
|
CP0514244
|
N-(2,6-difluorophenyl)-4-[2-methyl-4-[(6-morpholin-4-ylpyrido[3,4-d]pyrimidin-4-yl)amino]phenoxy]piperidine-1-carboxamide
Show/Hide
|
C30H31F2N7O3
|
1
|
1 |
IC50 = 16 nM
|
|
|
CP0384975
|
1-(4-(4-(6-(2-methoxyethoxy)quinazolin-4-ylamino)-2-methylphenoxy)piperidin-1-yl)-3,3-dimethylbutan-1-one
Show/Hide
|
C29H38N4O4
|
1
|
1 |
IC50 = 19 nM
|
|
|
CP0406565
|
N-(2,6-difluorophenyl)-4-[4-[[6-(dimethylamino)pyrido[3,4-d]pyrimidin-4-yl]amino]-2-methylphenoxy]piperidine-1-carboxamide
Show/Hide
|
C28H29F2N7O2
|
1
|
1 |
IC50 = 20 nM
|
|
|
CP0384972
|
4-(4-(6-(3-(2-methoxyacetamido)prop-1-ynyl)quinazolin-4-ylamino)-2-methylphenoxy)-N-neopentylbenzamide
Show/Hide
|
C33H35N5O4
|
1
|
1 |
IC50 = 23 nM
|
|
|
CP0049369
|
4-(2-methyl-4-(6-morpholinopyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)-N-neopentylbenzamide
Show/Hide
|
C30H34N6O3
|
1
|
1 |
IC50 = 24 nM
|
|
|
CP0496927
|
cyclopentyl-[4-[4-[[6-(2-methoxyethoxy)quinazolin-4-yl]amino]-2-methylphenoxy]piperidin-1-yl]methanone
Show/Hide
|
C29H36N4O4
|
1
|
1 |
IC50 = 29 nM
|
|
|
CP0529791
|
N-tert-butyl-3-[4-[[6-[3-[(2-methoxyacetyl)amino]prop-1-ynyl]quinazolin-4-yl]amino]-2-methylphenoxy]benzamide
Show/Hide
|
C32H33N5O4
|
1
|
1 |
IC50 = 30 nM
|
|
|
CP0406561
|
cyclopentyl-[4-[2-methyl-4-[(6-morpholin-4-ylpyrido[3,4-d]pyrimidin-4-yl)amino]phenoxy]piperidin-1-yl]methanone
Show/Hide
|
C29H36N6O3
|
1
|
1 |
IC50 = 33 nM
|
|
|
CP0439664
|
N-(2,6-difluorophenyl)-4-[4-[[6-(2-methoxyethoxy)quinazolin-4-yl]amino]-2-methylphenoxy]piperidine-1-carboxamide
Show/Hide
|
C30H31F2N5O4
|
1
|
1 |
IC50 = 33 nM
|
|
|
CP0486207
|
3,3-dimethyl-1-[4-[2-methyl-4-[[6-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]phenoxy]piperidin-1-yl]butan-1-one
Show/Hide
|
C33H45N5O4
|
1
|
1 |
IC50 = 34 nM
|
|
|
CP0486209
|
N-[3-[4-[4-[1-(cyclobutanecarbonyl)piperidin-4-yl]oxy-3-methylanilino]quinazolin-6-yl]prop-2-ynyl]-2-methoxyacetamide
Show/Hide
|
C31H35N5O4
|
1
|
1 |
IC50 = 51 nM
|
|
|
CP0467956
|
N-(2,6-difluorophenyl)-4-[2-methyl-4-[[6-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]phenoxy]piperidine-1-carboxamide
Show/Hide
|
C34H38F2N6O4
|
1
|
1 |
IC50 = 55 nM
|
|
|
CP0435598
|
N-(2,6-difluorophenyl)-4-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylphenoxy]piperidine-1-carboxamide
Show/Hide
|
C29H29F2N5O4
|
1
|
1 |
IC50 = 67 nM
|
|
|
CP0384979
|
N-[3-[4-[4-[1-(3-chlorobenzoyl)piperidin-4-yl]oxy-3-methylanilino]quinazolin-6-yl]prop-2-ynyl]-2-methoxyacetamide
Show/Hide
|
C33H32ClN5O4
|
1
|
1 |
IC50 = 75 nM
|
|
|
CP0496928
|
1-(4-(4-(6,7-dimethoxyquinazolin-4-ylamino)-2-methylphenoxy)piperidin-1-yl)-3,3-dimethylbutan-1-one
Show/Hide
|
C28H36N4O4
|
1
|
1 |
IC50 = 76 nM
|
|
|
CP0445841
|
3-(4-(6-(3-(2-methoxyacetamido)prop-1-ynyl)quinazolin-4-ylamino)-2-methylphenoxy)-N-neopentylbenzamide
Show/Hide
|
C33H35N5O4
|
1
|
1 |
IC50 = 110 nM
|
|
|
CP0541868
|
N-cyclobutyl-3-[4-[[6-[3-[(2-methoxyacetyl)amino]prop-1-ynyl]quinazolin-4-yl]amino]-2-methylphenoxy]benzamide
Show/Hide
|
C32H31N5O4
|
1
|
1 |
IC50 = 160 nM
|
|
|
CP0276148
|
4-N-(3-bromophenyl)-6-N-methylquinazoline-4,6-diamine
Show/Hide
|
C15H13BrN4
|
1
|
1 |
IC50 = 170 nM
|
|
|
CP0445814
|
N-(2,6-difluorophenyl)-4-[2-methyl-4-[[6-(methylamino)pyrido[3,4-d]pyrimidin-4-yl]amino]phenoxy]piperidine-1-carboxamide
Show/Hide
|
C27H27F2N7O2
|
1
|
1 |
IC50 = 180 nM
|
|
|
CP0406562
|
N-(2,6-difluorophenyl)-4-[4-[[6-[3-[(2-methoxyacetyl)amino]prop-1-ynyl]quinazolin-4-yl]amino]-2-methylphenoxy]piperidine-1-carboxamide
Show/Hide
|
C33H32F2N6O4
|
1
|
1 |
IC50 = 190 nM
|
|
|
CP0486211
|
N-(2,6-difluorophenyl)-4-[4-[(6-methoxyquinazolin-4-yl)amino]-2-methylphenoxy]piperidine-1-carboxamide
Show/Hide
|
C28H27F2N5O3
|
1
|
1 |
IC50 = 250 nM
|
|
|
CP0406564
|
4-(4-(6,7-dimethoxyquinazolin-4-ylamino)-2-methylphenoxy)-N-neopentylbenzamide
Show/Hide
|
C29H32N4O4
|
1
|
1 |
IC50 = 310 nM
|
|
|
CP0063852
|
(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({5-[(4-ethylpiperazin-1-yl)carbonyl]-3-methyl-1H-pyrrol-2-yl}methylidene)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
|
C25H25ClFN7O2
|
1
|
1 |
IC50 = 350 nM
|
|
|
CP0217755
|
(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({3-methyl-5-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl}methylidene)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
|
C24H23ClFN7O2
|
1
|
1 |
IC50 = 370 nM
|
|
|
CP0357546
|
5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-N-[2-(diethylamino)ethyl]-4-methyl-1H-pyrrole-2-carboxamide
Show/Hide
|
C25H27ClFN7O2
|
1
|
1 |
IC50 = 370 nM
|
|
|
CP0201108
|
5-{[(5Z)-4-[(3-ethynylphenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide
Show/Hide
|
C27H27N7O3
|
1
|
1 |
IC50 = 500 nM
|
|
|
CP0204735
|
(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({5-[(3,5-dimethylpiperazin-1-yl)carbonyl]-3-methyl-1H-pyrrol-2-yl}methylidene)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
|
C25H25ClFN7O2
|
1
|
1 |
IC50 = 510 nM
|
|
|
CP0467957
|
1-(4-(4-(6,7-bis(2-methoxyethoxy)quinazolin-4-ylamino)-2-methylphenoxy)piperidin-1-yl)-3,3-dimethylbutan-1-one
Show/Hide
|
C32H44N4O6
|
1
|
1 |
IC50 = 530 nM
|
|
|
CP0486205
|
(4-(4-(6,7-bis(2-methoxyethoxy)quinazolin-4-ylamino)-2-methylphenoxy)piperidin-1-yl)(cyclopentyl)methanone
Show/Hide
|
C32H42N4O6
|
1
|
1 |
IC50 = 530 nM
|
|
|
CP0138773
|
4-Anilinoquinazoline deriv. 45
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|
C14H11BrN4
|
1
|
1 |
IC50 = 670 nM
|
|
|
CP0293174
|
1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-chloro-phenyl)amino]quinazolin-6-yl}urea
Show/Hide
|
C18H16Cl2N6O2
|
1
|
1 |
IC50 = 680 nM
|
|
|
CP0435603
|
4-(4-(6,7-bis(2-methoxyethoxy)quinazolin-4-ylamino)-2-methylphenoxy)-N-(2,6-difluorophenyl)piperidine-1-carboxamide
Show/Hide
|
C33H37F2N5O6
|
1
|
1 |
IC50 = 840 nM
|
|
|
CP0328172
|
4-[(3-chlorophenyl)amino]-6-(methylamino)quinazoline
Show/Hide
|
C15H13ClN4
|
1
|
1 |
IC50 = 890 nM
|
|
|
CP0343594
|
1-(2-chloroethyl)-1-nitroso-3-{[4-(3-bromophenyl)amino]quinazolin-6-yl}urea
Show/Hide
|
C17H14BrClN6O2
|
1
|
1 |
IC50 = 1150 nM
|
|
|
CP0084269
|
(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
|
C23H20ClFN6O3
|
1
|
1 |
IC50 = 1210 nM
|
|
|
CP0088175
|
5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide
Show/Hide
|
C25H25ClFN7O3
|
1
|
1 |
IC50 = 1240 nM
|
|
|
CP0197387
|
1-(2-chloroethyl)-3-{[4-(3-chlorophenyl)amino]quinazolin-6-yl}urea
Show/Hide
|
C17H15Cl2N5O
|
1
|
1 |
IC50 = 1350 nM
|
|
|
CP0041166
|
5-{[(5Z)-4-[(1-benzyl-1H-indol-5-yl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide
Show/Hide
|
C34H34N8O3
|
1
|
1 |
IC50 = 1560 nM
|
|
|
CP0455094
|
1-(2-chloroethyl)-3-{[4-(3-bromophenyl)amino]quinazolin-6-yl}urea
Show/Hide
|
C17H15BrClN5O
|
1
|
1 |
IC50 = 1770 nM
|
|
|
CP0532346
|
4-[(3-methylphenyl)amino]-6-(methylamino)quinazoline
Show/Hide
|
C16H16N4
|
1
|
1 |
IC50 = 2070 nM
|
|
|
CP0520193
|
1-(2-chloroethyl)-3-{[4-(3-methylphenyl)amino]quinazolin-6-yl}urea
Show/Hide
|
C18H18ClN5O
|
1
|
1 |
IC50 = 2100 nM
|
|
|
CP0217745
|
(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
|
C19H15ClFN5O
|
1
|
1 |
IC50 = 2500 nM
|
|
|
CP0255898
|
(5Z)-4-(2,3-dihydro-1H-inden-5-ylamino)-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
|
C26H26N6O3
|
1
|
1 |
IC50 = 2780 nM
|
|
|
CP0384978
|
2-methoxy-N-[3-(4-{3-methyl-4-[1-(tetrahydro-furan-2-carbonyl)-piperidin-4-yloxy]-phenylamino}-quinazolin-6-yl)-prop-2-ynyl]-acetamide
Show/Hide
|
C31H35N5O5
|
1
|
1 |
IC50 = 2900 nM
|
|
|
CP0190700
|
1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-bromophenyl)amino]quinazolin-6-yl}urea
Show/Hide
|
C18H16BrClN6O2
|
1
|
1 |
IC50 = 3060 nM
|
|
|
CP0190702
|
Anilinoquinazoline, 4c
Show/Hide
|
C14H11ClN4
|
1
|
1 |
IC50 = 3290 nM
|
|
|
CP0341988
|
1-(2-Chloroethyl)-1-nitroso-3-{[4-(3-chlorophenyl)amino]quinazolin-6-yl}urea
Show/Hide
|
C17H14Cl2N6O2
|
1
|
1 |
IC50 = 5400 nM
|
|
|
CP0048287
|
Anilinoquinazoline, 4a
Show/Hide
|
C15H14N4
|
1
|
1 |
IC50 = 6390 nM
|
|
|
CP0340557
|
1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-methylphenyl)amino]quinazolin-6-yl}urea
Show/Hide
|
C19H19ClN6O2
|
1
|
1 |
IC50 = 6880 nM
|
|
|
CP0341989
|
3-(2-chloroethyl)-1-methyl-1-{[4-(3-bromophenyl)amino]quinazolin-6-yl}urea
Show/Hide
|
C18H17BrClN5O
|
1
|
1 |
IC50 = 11080 nM
|
|
|
CP0293175
|
3-(2-chloroethyl)-1-methyl-1-{[4-(3-methylphenyl)amino]quinazolin-6-yl}urea
Show/Hide
|
C19H20ClN5O
|
1
|
1 |
IC50 = 11800 nM
|
|
|
CP0503940
|
1-(2-Chloroethyl)-1-nitroso-3-{[4-(3-methylphenyl)amino]quinazolin-6-yl}urea
Show/Hide
|
C18H17ClN6O2
|
1
|
1 |
IC50 = 12180 nM
|
|
|
CP0190701
|
3-(2-chloroethyl)-1-methyl-1-{[4-(3-chlorophenyl)amino]quinazolin-6-yl}urea
Show/Hide
|
C18H17Cl2N5O
|
1
|
1 |
IC50 = 23030 nM
|
|
|
CP0358290
|
5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-4-methyl-1H-pyrrole-2-carboxylic acid
Show/Hide
|
C19H13ClFN5O3
|
1
|
1 |
IC50 = 49300 nM
|
|
|