Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-cyclobutyl-3-[4-[[6-[3-[(2-methoxyacetyl)amino]prop-1-ynyl]quinazolin-4-yl]amino]-2-methylphenoxy]benzamide
    Show/Hide
 PubChem ID
CID: 44426267
Canonical SMILES
COCC(=O)NCC#Cc1ccc2ncnc(Nc3ccc(Oc4cccc(c4)C(=O)NC4CCC4)c(C)c3)c2c1
    Show/Hide
Compound Formula C32H31N5O4
Compound Structure
Protein Name
 Protein Info 
Receptor tyrosine-protein kinase erbB-2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P04626
Gene Name
ERBB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 160 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 230 nM
   TI
   LI
   LO
   TS