Brief Information of the Cell Line and Protein
Cell Line ID: CL000035 , NIH 3T3
Synonyms
NIH/3T3
NIH-3T3
NIH3T3
3T3
3T3NIH
3T3-Swiss
Swiss-3T3
Swiss/3T3
Swiss 3T3
Swiss3T3
Category Spontaneously immortalized cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0594
Protein ID: PT00934 , High affinity nerve growth factor receptor
Gene Name NTRK1
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P04629
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000035  Protein ID: PT00934
 
Compound ID Compound Name Compound Formula
CP0020453
US10081622, Compound 11
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C31H34F2N6O2
 3
1
IC50 = 0.22 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.9 nM
   TI
   LI
   LO
   TS
3
IC50 = 45 nM
   TI
   LI
   LO
   TS
CP0273324
N-tert-butyl-2-[2-[8-(methanesulfonamido)-6,6-dimethyl-11-oxonaphtho[2,3-b][1]benzofuran-3-yl]ethynyl]-6-methylpyridine-4-carboxamide
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C32H31N3O5S
 3
1
IC50 = 0.68 nM
   TI
   LI
   LO
   TS
2
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
3
IC50 = 83 nM
   TI
   LI
   LO
   TS