| Compound ID |
Compound Name |
Compound Formula |
|
CP0190487
|
2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]-8-(pyrrolidin-3-ylmethoxy)quinoline
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|
C24H26N4O3
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 = 29 nM
|
|
|
|
CP0190489
|
8-[(4-fluoropiperidin-4-yl)methoxy]-2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]quinoline
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|
C25H27FN4O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0134161
|
(3S,4R)-4-[2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]quinolin-8-yl]oxypiperidin-3-ol
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|
C24H26N4O4
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0074198
|
(3R,4R)-4-[2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]quinolin-8-yl]oxypiperidin-3-ol
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|
C24H26N4O4
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0074200
|
2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]-8-piperidin-4-yloxyquinoline
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|
C24H26N4O3
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 25 nM
|
|
|
|
CP0154064
|
8-[(3S,4S)-3-fluoropiperidin-4-yl]oxy-2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]quinoline
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|
C24H25FN4O3
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 55 nM
|
|
|
|
CP0074195
|
8-[(3S,4R)-3-fluoropiperidin-4-yl]oxy-2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]quinoline
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|
C24H25FN4O3
|
2
|
| 1 |
IC50 = 4 nM
|
|
|
| 2 |
IC50 = 25 nM
|
|
|
|
CP0172713
|
2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]-8-[(3S)-piperidin-3-yl]oxyquinoline
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|
C24H26N4O3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0256870
|
2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]-8-(1-methylpiperidin-4-yl)oxyquinoline
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|
C25H28N4O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0201309
|
2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]-8-[(3R,4R)-4-methoxypyrrolidin-3-yl]oxyquinoline
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|
C24H26N4O4
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0074199
|
3-[2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]quinolin-8-yl]oxy-2,2-dimethylpropan-1-amine
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|
C24H28N4O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0221620
|
CHEMBL3109348
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|
C25H28N4O3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0202904
|
2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]-8-(piperidin-4-ylmethoxy)quinoline
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|
C25H28N4O3
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0256869
|
2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]-8-[(3R)-piperidin-3-yl]oxyquinoline
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|
C24H26N4O3
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0074197
|
2-[[2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]quinolin-8-yl]oxymethyl]morpholine
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|
C24H26N4O4
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0134158
|
2-[2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]quinolin-8-yl]oxyethanamine
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|
C21H22N4O3
|
1
|
| 1 |
IC50 = 176 nM
|
|
|
|
CP0074194
|
methyl (2S,4R)-4-[2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]quinolin-8-yl]oxypyrrolidine-2-carboxylate
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|
C25H26N4O5
|
1
|
| 1 |
IC50 = 958 nM
|
|
|
|
CP0221617
|
methyl (2S,4S)-4-[2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]quinolin-8-yl]oxypyrrolidine-2-carboxylate
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|
C25H26N4O5
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0258059
|
8-(1H-imidazol-5-ylmethoxy)-2-[7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl]quinoline
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|
C23H21N5O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
