General Information of the Compound
Compound ID
CP0221620
Compound Name
CHEMBL3109348
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Formula
C25H28N4O3
Molecular Weight
432.524
Canonical SMILES
COCCOc1ccn2c(cnc2c1)-c1ccc2cccc(O[C@H]3CC[C@H](N)CC3)c2n1
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InChI
InChI=1S/C25H28N4O3/c1-30-13-14-31-20-11-12-29-22(16-27-24(29)15-20)21-10-5-17-3-2-4-23(25(17)28-21)32-19-8-6-18(26)7-9-19/h2-5,10-12,15-16,18-19H,6-9,13-14,26H2,1H3/t18-,19-
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InChIKey
QQQWALLKBNQXFJ-WGSAOQKQSA-N
Physicochemical Property
logP
4.2234
Rotatable Bonds
7
Heavy Atom Count
32
Polar Areas
83.9
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
SID: 56417764
ChEMBL ID
CHEMBL3109348
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00832, Platelet-derived growth factor receptor beta
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 28 nM
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