Brief Information of the Cell Line and Protein
Cell Line ID: CL000031 , MDCK
 Cell Line Info 
Synonyms
MDCK (NBL-2)
MDCK(NBL-2)
NBL-2
Madin-Darby Canine Kidney
Madin Darby Canine Kidney
Category Spontaneously immortalized cell line
Organism
Canis lupus familiaris (Dog)
Cellosaurus ID
CVCL_0422
Protein ID: PT03505 , Ileal sodium/bile acid cotransporter
 Protein Info 
Gene Name SLC10A2
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID Q12908
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000031
 Cell Line Info 
 Protein ID: PT03505
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0509718
 Compound Info 
(2S)-5-(4-tert-butylphenylamino)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxopentanoate
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C39H60N2O6
  1
1
Ki = 275 nM
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CP0504099
 Compound Info 
(2S)-5-(3-tert-butylphenylamino)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxopentanoate
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C39H60N2O6
  1
1
Ki = 587 nM
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CP0476439
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxo-5-(m-tolylamino)pentanoate
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C36H54N2O6
  1
1
Ki = 889 nM
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CP0912171
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-(2-(ethoxycarbonyl)phenylamino)-5-oxopentanoate
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C38H56N2O8
  1
1
Ki = 1150 nM
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CP0493555
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-(3-fluorophenylamino)-5-oxopentanoate
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C35H51FN2O6
  1
1
Ki = 1250 nM
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CP0479161
 Compound Info 
(S)-5-(4-chlorophenylamino)-2-((R)-4-((3R,5R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxopentanoate
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C35H51ClN2O6
  1
1
Ki = 1910 nM
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CP0932354
 Compound Info 
(S)-2-((R)-4-((3R,5R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxo-5-(phenylamino)pentanoate
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C35H52N2O6
  1
1
Ki = 2010 nM
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CP0401905
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxo-5-(4-(trifluoromethyl)phenylamino)pentanoate
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C36H51F3N2O6
  1
1
Ki = 2020 nM
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CP0913146
 Compound Info 
3-((S)-5-(benzylperoxy)-4-((R)-4-((3R,5R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxopentanamido)benzoic acid
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C43H58N2O9
  1
1
Ki = 2240 nM
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CP0473126
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-(2-(methoxycarbonyl)phenylamino)-5-oxopentanoate
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C37H54N2O8
  1
1
Ki = 2300 nM
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CP0433676
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-(2-fluorophenylamino)-5-oxopentanoate
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C35H51FN2O6
  1
1
Ki = 2310 nM
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CP0514914
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxo-5-(o-tolylamino)pentanoate
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C36H54N2O6
  1
1
Ki = 2630 nM
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CP0520821
 Compound Info 
(2S)-5-(2-aminophenylamino)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxopentanoate
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C35H53N3O6
  1
1
Ki = 2640 nM
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CP0502319
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-(4-fluorophenylamino)-5-oxopentanoate
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C35H51FN2O6
  1
1
Ki = 3020 nM
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CP0487834
 Compound Info 
(2S)-5-(2,4-difluorophenylamino)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxopentanoate
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C35H50F2N2O6
  1
1
Ki = 3160 nM
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CP0400432
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxo-5-(p-tolylamino)pentanoate
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C36H54N2O6
  1
1
Ki = 3200 nM
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CP0428891
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-(2-methoxyphenylamino)-5-oxopentanoate
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C36H54N2O7
  1
1
Ki = 3890 nM
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CP0428892
 Compound Info 
(2S)-5-(2-tert-butylphenylamino)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxopentanoate
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C39H60N2O6
  1
1
Ki = 3930 nM
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CP0509340
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-(4-(methoxycarbonyl)phenylamino)-5-oxopentanoate
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C37H54N2O8
  1
1
Ki = 4030 nM
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CP0418479
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-(3-methoxyphenylamino)-5-oxopentanoate
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C36H54N2O7
  1
1
Ki = 4220 nM
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CP0496025
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-(2,3-dimethylphenylamino)-5-oxopentanoate
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C37H56N2O6
  1
1
Ki = 4300 nM
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CP0903599
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-(4-(ethoxycarbonyl)phenylamino)-5-oxopentanoate
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C38H56N2O8
  1
1
Ki = 5160 nM
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CP0509342
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-(3,5-dimethoxyphenylamino)-5-oxopentanoate
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C37H56N2O8
  1
1
Ki = 5190 nM
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CP0903600
 Compound Info 
(2S)-5-(4-(tert-butoxycarbonylamino)phenylamino)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxopentanoate
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C40H61N3O8
  1
1
Ki = 5260 nM
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CP0536779
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-(4-methoxyphenylamino)-5-oxopentanoate
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C36H54N2O7
  1
1
Ki = 6090 nM
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CP0925825
 Compound Info 
(2S)-5-(3-(tert-butoxycarbonylamino)phenylamino)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxopentanoate
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C40H61N3O8
  1
1
Ki = 6530 nM
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CP0509719
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-(3-(methoxycarbonyl)phenylamino)-5-oxopentanoate
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C37H54N2O8
  1
1
Ki = 7650 nM
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CP0509341
 Compound Info 
(2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-(2,6-dimethylphenylamino)-5-oxopentanoate
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C37H56N2O6
  1
1
Ki = 8070 nM
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CP0416636
 Compound Info 
(2S)-5-(4-aminophenylamino)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxopentanoate
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C35H53N3O6
  1
1
Ki = 15900 nM
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CP0490890
 Compound Info 
(2S)-5-(3-aminophenylamino)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxopentanoate
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C35H53N3O6
  1
1
Ki = 16300 nM
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CP0487835
 Compound Info 
3-((4S)-4-carboxylato-4-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)butanamido)benzoate
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C36H52N2O8
  1
1
Ki = 35900 nM
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CP0489447
 Compound Info 
2-((S)-4-carboxy-4-((R)-4-((3R,5R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)butanamido)benzoic acid
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C36H52N2O8
  1
1
Ki = 40400 nM
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CP0496026
 Compound Info 
4-(((4S)-4-carboxylato-4-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)butanamido)methyl)benzoate
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C37H54N2O8
  1
1
Ki = 41000 nM
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