General Information of the Compound
Compound ID
CP0932354
Compound Name
(S)-2-((R)-4-((3R,5R,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)-5-oxo-5-(phenylamino)pentanoate
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Structure
Formula
C35H52N2O6
Molecular Weight
596.809
Canonical SMILES
CC(CCC(=O)NC(CCC(=O)Nc1ccccc1)C(=O)O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C
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InChI
InChI=1S/C35H52N2O6/c1-21(9-13-31(41)37-28(33(42)43)12-14-30(40)36-23-7-5-4-6-8-23)25-10-11-26-32-27(16-18-35(25,26)3)34(2)17-15-24(38)19-22(34)20-29(32)39/h4-8,21-22,24-29,32,38-39H,9-20H2,1-3H3,(H,36,40)(H,37,41)(H,42,43)
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InChIKey
YVZZWDGPBJHUST-UHFFFAOYSA-N
Physicochemical Property
logP
5.3816
Rotatable Bonds
10
Heavy Atom Count
43
Polar Areas
135.96
Hydrogen Bond Donor Count
5
Hydrogen Bond Acceptor Count
5
Complexity
43

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 56681532
ChEMBL ID
CHEMBL3138513
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03505, Ileal sodium/bile acid cotransporter
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000031 MDCK Canis lupus familiaris (Dog)  1
1
Ki = 2010 nM
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   LI
   LO
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