| Compound ID |
Compound Name |
Compound Formula |
|
CP0468624
|
(2S,3S)-3-[[2-(5-fluoro-2H-pyrazolo[3,4-b]pyridin-3-yl)thieno[2,3-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C21H19FN6O2S
|
1
|
| 1 |
EC50 = 0.06 nM
|
|
|
|
CP0429621
|
(2S,3S)-3-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)thieno[2,3-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C22H20FN5O2S
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0482034
|
(2S,3S)-3-[[2-(5-fluoro-2H-pyrazolo[3,4-b]pyridin-3-yl)-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C21H21FN6O2S
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0567305
|
(2S,3S)-3-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C22H22FN5O2S
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0458025
|
(2S,3S)-3-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)thieno[3,2-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C22H20FN5O2S
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0519460
|
(2S,3S)-3-[[2-(5-fluoro-2H-pyrazolo[3,4-b]pyridin-3-yl)thieno[3,2-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C21H19FN6O2S
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0100388
|
(2S,3S)-3-[[5-fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C20H19F2N5O2
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
|
CP0549184
|
(2S,3S)-3-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)thieno[3,4-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C22H20FN5O2S
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0519459
|
(2S,3S)-3-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C22H22FN5O2S
|
1
|
| 1 |
EC50 = 2.6 nM
|
|
|
|
CP0549186
|
(2S,3S)-3-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5,6-dihydrothieno[2,3-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C22H22FN5O2S
|
1
|
| 1 |
EC50 = 2.8 nM
|
|
|
|
CP0446068
|
(2S,3S)-3-[[5-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C21H19FN6O2S
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0549183
|
(2S,3S)-3-[[7-cyano-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)thieno[3,2-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C23H19FN6O2S
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0954106
|
(2S,3S)-3-((2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C22H21FN6O2
|
1
|
| 1 |
EC50 = 4.5 nM
|
|
|
|
CP0567304
|
(2S,3S)-3-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)furo[3,2-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C22H20FN5O3
|
1
|
| 1 |
EC50 = 5.3 nM
|
|
|
|
CP0557238
|
(2S,3S)-3-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C23H24FN5O2
|
1
|
| 1 |
EC50 = 5.5 nM
|
|
|
|
CP0554943
|
(2S,3S)-3-[[5-fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-7-methylpyrrolo[2,3-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C23H22F2N6O2
|
1
|
| 1 |
EC50 = 9.6 nM
|
|
|
|
CP0482032
|
(2S,3S)-3-[[6-(difluoromethyl)-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)thieno[3,2-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C23H20F3N5O2S
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0549176
|
(2S,3S)-3-[[7-fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrido[3,2-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C23H20F2N6O2
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0446067
|
(2S,3S)-3-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-7-methylpyrido[3,2-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C24H23FN6O2
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0554942
|
(2S,3S)-3-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-methylquinazolin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C25H24FN5O2
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0458024
|
(2S,3S)-3-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5,6,7,8-tetrahydroquinazolin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C24H26FN5O2
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0473817
|
(2S,3S)-3-[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrrolo[2,3-d]pyrimidin-7-yl]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C22H20FN5O2
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0468623
|
(2S,3S)-3-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pteridin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C22H20FN7O2
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0458023
|
(2S,3S)-3-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrido[3,2-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C23H21FN6O2
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0567303
|
(2S,3S)-3-[[5-fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)quinazolin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C24H21F2N5O2
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0554941
|
(2S,3S)-3-[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-6,7-dihydropyrimido[5,4-b][1,4]oxazin-8-yl]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C22H22FN5O3
|
1
|
| 1 |
EC50 = 24 nM
|
|
|
|
CP0563552
|
(2S,3S)-3-[5-cyano-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrrolo[2,3-d]pyrimidin-7-yl]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C23H19FN6O2
|
1
|
| 1 |
EC50 = 70 nM
|
|
|
|
CP0559670
|
(2S,3S)-3-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5,5-dioxo-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C22H22FN5O4S
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0446066
|
(2S,3S)-3-[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)purin-9-yl]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C21H19FN6O2
|
1
|
| 1 |
EC50 = 190 nM
|
|
|
|
CP0519462
|
(2S,3S)-3-[[5-fluoro-2-(5-fluoro-1H-indol-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C21H20F2N4O2
|
1
|
| 1 |
EC50 = 220 nM
|
|
|
|
CP0559671
|
(2S,3S)-3-[[5-fluoro-2-(6-fluoropyrrolo[3,2-b]pyridin-1-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C20H19F2N5O2
|
1
|
| 1 |
EC50 = 230 nM
|
|
|
|
CP0559672
|
(2S,3S)-3-[[4-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-methylquinazolin-2-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C25H24FN5O2
|
1
|
| 1 |
EC50 = 450 nM
|
|
|
|
CP0482033
|
(2S,3S)-3-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-6,6-dioxo-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
Show/Hide
|
C22H22FN5O4S
|
1
|
| 1 |
EC50 = 2000 nM
|
|
|
