Brief Information of the Cell Line and Protein
Cell Line ID: CL000031 , MDCK
Synonyms
MDCK (NBL-2)
MDCK(NBL-2)
NBL-2
Madin-Darby Canine Kidney
Madin Darby Canine Kidney
Category Spontaneously immortalized cell line
Organism
Canis lupus familiaris (Dog)
Cellosaurus ID
CVCL_0422
Protein ID: PT03153 , Urea transporter 1
Gene Name SLC14A1
Organism Mus musculus, Mouse
Protein Classification Transporter
Uniprot ID Q8VHL0
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000031  Protein ID: PT03153
 
Compound ID Compound Name Compound Formula
CP0528091
5-acetyl-N-[4-(benzenesulfonamido)phenyl]furan-2-carboxamide
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C19H16N2O5S
 1
1
IC50 = 160 nM
   TI
   LI
   LO
   TS
CP0552816
N-[4-(benzenesulfonamido)phenyl]-5-nitrofuran-2-carboxamide
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C17H13N3O6S
 1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS
CP0367814
N-(4-acetamidophenyl)-5-acetylfuran-2-carboxamide
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C15H14N2O4
 1
1
IC50 = 480 nM
   TI
   LI
   LO
   TS
CP0577404
N-[4-[(4-chlorophenyl)sulfonylamino]phenyl]-5-nitrofuran-2-carboxamide
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C17H12ClN3O6S
 1
1
IC50 = 690 nM
   TI
   LI
   LO
   TS
CP0528089
N-[4-(ethylsulfonylamino)phenyl]-5-nitrofuran-2-carboxamide
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C13H13N3O6S
 1
1
IC50 = 840 nM
   TI
   LI
   LO
   TS
CP0528090
N-[4-[(3-chlorophenyl)sulfonylamino]phenyl]-5-nitrofuran-2-carboxamide
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C17H12ClN3O6S
 1
1
IC50 = 1010 nM
   TI
   LI
   LO
   TS
CP0574779
N-[4-[(2-chlorophenyl)sulfonylamino]phenyl]-5-nitrofuran-2-carboxamide
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C17H12ClN3O6S
 1
1
IC50 = 1050 nM
   TI
   LI
   LO
   TS
CP0574778
N-[4-[(4-fluorophenyl)sulfonylamino]phenyl]-5-nitrofuran-2-carboxamide
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C17H12FN3O6S
 1
1
IC50 = 1310 nM
   TI
   LI
   LO
   TS
CP0543948
N-[4-[(3-fluorophenyl)sulfonylamino]phenyl]-5-nitrofuran-2-carboxamide
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C17H12FN3O6S
 1
1
IC50 = 1320 nM
   TI
   LI
   LO
   TS
CP0495336
5-nitro-N-[4-[[2-(trifluoromethyl)phenyl]sulfonylamino]phenyl]furan-2-carboxamide
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C18H12F3N3O6S
 1
1
IC50 = 1490 nM
   TI
   LI
   LO
   TS
CP0543945
5-nitro-N-(2-oxo-1H-quinolin-7-yl)furan-2-carboxamide
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C14H9N3O5
 1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0543949
N-[4-[(3-bromophenyl)sulfonylamino]phenyl]-5-nitrofuran-2-carboxamide
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C17H12BrN3O6S
 1
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS
CP0547726
N-[4-[(2-fluorophenyl)sulfonylamino]phenyl]-5-nitrofuran-2-carboxamide
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C17H12FN3O6S
 1
1
IC50 = 1680 nM
   TI
   LI
   LO
   TS
CP0543947
5-nitro-N-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)furan-2-carboxamide
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C14H11N3O5
 1
1
IC50 = 2190 nM
   TI
   LI
   LO
   TS
CP0578022
5-nitro-N-[4-[[3-(trifluoromethyl)phenyl]sulfonylamino]phenyl]furan-2-carboxamide
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C18H12F3N3O6S
 1
1
IC50 = 2220 nM
   TI
   LI
   LO
   TS
CP0543068
5-nitro-N-(2-oxo-1H-quinolin-6-yl)furan-2-carboxamide
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C14H9N3O5
 1
1
IC50 = 2340 nM
   TI
   LI
   LO
   TS
CP0552817
5-nitro-N-[4-[[4-(trifluoromethyl)phenyl]sulfonylamino]phenyl]furan-2-carboxamide
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C18H12F3N3O6S
 1
1
IC50 = 3470 nM
   TI
   LI
   LO
   TS
CP0545581
5-nitro-N-(2-oxo-1,3-dihydroindol-5-yl)furan-2-carboxamide
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C13H9N3O5
 1
1
IC50 = 4990 nM
   TI
   LI
   LO
   TS
CP0543071
N-(4-acetamidophenyl)-5-nitrofuran-2-carboxamide
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C13H11N3O5
 1
1
IC50 = 5820 nM
   TI
   LI
   LO
   TS
CP0528092
N-(4-acetamidophenyl)-5-benzoylfuran-2-carboxamide
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C20H16N2O4
 1
1
IC50 = 9850 nM
   TI
   LI
   LO
   TS
CP0543946
5-nitro-N-(2-oxo-1H-quinolin-5-yl)furan-2-carboxamide
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C14H9N3O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0543950
N-(4-acetamidophenyl)-5-(difluoromethyl)furan-2-carboxamide
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C14H12F2N2O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0545583
N-(4-acetamidophenyl)-5-(2,2-dimethylpropanoyl)furan-2-carboxamide
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C18H20N2O4
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0552815
5-nitro-N-(2-oxo-1H-quinolin-8-yl)furan-2-carboxamide
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C14H9N3O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0552818
N-(4-acetamidophenyl)-5-fluorofuran-2-carboxamide
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C13H11FN2O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS