Brief Information of the Cell Line and Protein
Cell Line ID: CL000031 , MDCK
Synonyms
MDCK (NBL-2)
MDCK(NBL-2)
NBL-2
Madin-Darby Canine Kidney
Madin Darby Canine Kidney
Category Spontaneously immortalized cell line
Organism
Canis lupus familiaris (Dog)
Cellosaurus ID
CVCL_0422
Protein ID: PT01650 , Alpha-2A adrenergic receptor
Gene Name ADRA2A
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P08913
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000031  Protein ID: PT01650
 
Compound ID Compound Name Compound Formula
CP0117807
4-[4-[1-[4-[1-(6-aminohexyl)triazol-4-yl]butyl]piperidin-4-yl]phenyl]-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid
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C41H46F3N5O2
 1
1
Ki = 28 nM
   TI
   LI
   LO
   TS
CP0127400
(-)-Pramipexole
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C10H17N3S
 1
1
Ki = 75.7 nM
   TI
   LI
   LO
   TS
CP0066194
N-[2-(1,3-benzodioxol-5-yl)ethyl]-N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenylpropan-1-amine
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C28H33NO4
 1
1
Ki = 102 nM
   TI
   LI
   LO
   TS
CP0001212
1-(2-methoxyphenyl)-4-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]piperazine
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C23H29N5OS
 1
1
Ki = 221 nM
   TI
   LI
   LO
   TS
CP0389575
4-(2-benzyl-3,4-dihydro-1H-isoquinolin-6-yl)morpholine
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C20H24N2O
 1
1
Ki = 321 nM
   TI
   LI
   LO
   TS
CP0411059
(3S,4S)-4-ethyl-3-methyl-1-phenyl-2,4-dihydroquinolin-3-amine
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C18H22N2
 1
1
Ki = 398.11 nM
   TI
   LI
   LO
   TS
CP0335097
benzyl 5-(4-methylpiperazin-1-yl)-1,3-dihydroisoindole-2-carboxylate
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C21H25N3O2
 1
1
Ki = 487 nM
   TI
   LI
   LO
   TS
CP0073146
benzyl 7-(4-cyclopentylpiperazin-1-yl)-3,4-dihydro-1H-isoquinoline-2-carboxylate
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C26H33N3O2
 1
1
Ki = 506 nM
   TI
   LI
   LO
   TS
CP0248167
benzyl 7-[4-(2-methylprop-2-enyl)piperazin-1-yl]-3,4-dihydro-1H-isoquinoline-2-carboxylate
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C25H31N3O2
 1
1
Ki = 876 nM
   TI
   LI
   LO
   TS
CP0482695
3-[4-(5-chlorothiophen-2-yl)triazol-1-yl]-5-(4-piperidin-4-ylphenyl)benzoic acid
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C24H21ClN4O2S
 1
1
Ki = 1560 nM
   TI
   LI
   LO
   TS
CP0054519
(1R,12R,13S,17R,21S)-12-ethyl-18-propyl-7-(trifluoromethyl)-10,18-diazapentacyclo[11.7.1.02,11.04,9.017,21]henicosa-2(11),3,5,7,9-pentaene
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C25H31F3N2
 1
1
Ki = 1586 nM
   TI
   LI
   LO
   TS
CP0248165
2-benzyl-5-(3-methoxyphenyl)-1,3-dihydroisoindole
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C22H21NO
 1
1
Ki = 1685 nM
   TI
   LI
   LO
   TS
CP0327799
4-(2-benzyl-1,3-dihydroisoindol-5-yl)morpholine
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C19H22N2O
 1
1
Ki = 2089 nM
   TI
   LI
   LO
   TS
CP0244206
7-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]thieno[2,3-c]pyridine
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C21H12F3N3OS
 1
1
Ki = 2600 nM
   TI
   LI
   LO
   TS
CP0064183
4-[3-methyl-4-(6-methylimidazo[1,2-a]pyrazin-5-yl)phenoxy]furo[3,2-c]pyridine
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C21H16N4O2
 1
1
Ki = 3400 nM
   TI
   LI
   LO
   TS
CP0369306
4-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine
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C21H12F3N3O2
 1
1
Ki = 5100 nM
   TI
   LI
   LO
   TS
CP0415883
4-[4-[1-[4-[1-[6-[(2-methylpropan-2-yl)oxycarbonylamino]hexyl]triazol-4-yl]butyl]piperidin-4-yl]phenyl]-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid
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C46H54F3N5O4
 1
1
Ki = 5280 nM
   TI
   LI
   LO
   TS
CP0391120
(1S,2R)-1-ethyl-7-methoxy-2-methyl-3,4-dihydro-1H-naphthalen-2-amine
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C14H21NO
 1
1
Ki = 6309.57 nM
   TI
   LI
   LO
   TS
CP0064188
4-[4-(6-methylimidazo[1,2-a]pyrazin-5-yl)-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine
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C21H13F3N4O2
 1
1
Ki = 6800 nM
   TI
   LI
   LO
   TS
CP0002071
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-prop-2-enylprop-2-en-1-amine
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C17H22N2O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0085414
(3aS,6R,6aS,9aR,9bR)-6-benzyl-1-methyl-3,3a,4,6,6a,7,8,9,9a,9b-decahydro-2H-benzo[de]quinolin-5-one
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C20H27NO
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0391121
(3S,4S)-4-ethyl-3,6-dimethyl-2,4-dihydrochromen-3-amine
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C13H19NO
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0137322
1H-indol-2-yl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
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C22H25N3O3
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS