| Compound ID |
Compound Name |
Compound Formula |
|
CP0687592
|
(Z)-4-[4-[(4-chlorophenyl)methyl]-1-(cyclohexylmethyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid
Show/Hide
|
C23H30ClNO4
|
1
|
| 1 |
EC50 = 800 nM
|
|
|
|
CP0109317
|
(Z)-4-[1-benzyl-4-[(4-chlorophenyl)methyl]piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid
Show/Hide
|
C23H24ClNO4
|
1
|
| 1 |
EC50 = 860 nM
|
|
|
|
CP0115435
|
4-hydroxy-2-oxo-4-(4-phenoxyphenyl)but-3-enoic acid
Show/Hide
|
C16H12O5
|
1
|
| 1 |
EC50 = 1450 nM
|
|
|
|
CP0410191
|
5-hydroxy-6-oxo-N-[(1R)-1-phenylethyl]-2-pyrazin-2-yl-1H-pyrimidine-4-carboxamide
Show/Hide
|
C17H15N5O3
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
|
CP0847636
|
4-hydroxy-2-oxo-4-(4-piperazin-1-ylphenyl)but-3-enoic acid
Show/Hide
|
C14H16N2O4
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
|
CP0036531
|
4-hydroxy-2-oxo-4-phenylbut-3-enoic acid
Show/Hide
|
C10H8O4
|
1
|
| 1 |
EC50 = 2070 nM
|
|
|
|
CP0089024
|
2-hydroxy-4H-isoquinoline-1,3-dione
Show/Hide
|
C9H7NO3
|
1
|
| 1 |
EC50 = 3220 nM
|
|
|
|
CP0271229
|
5-hydroxy-6-oxo-N-(1-phenylethyl)-2-pyrazin-2-yl-1H-pyrimidine-4-carboxamide
Show/Hide
|
C17H15N5O3
|
1
|
| 1 |
EC50 = 3500 nM
|
|
|
|
CP0271261
|
5-hydroxy-N-[(1S)-2-hydroxy-1-phenylethyl]-6-oxo-2-pyrazin-2-yl-1H-pyrimidine-4-carboxamide
Show/Hide
|
C17H15N5O4
|
1
|
| 1 |
EC50 = 3500 nM
|
|
|
|
CP0713308
|
2-Hydroxy-4-(biphenyl-4-yl)-4-oxobut-2-enoic acid
Show/Hide
|
C16H12O4
|
1
|
| 1 |
EC50 = 3560 nM
|
|
|
|
CP0338376
|
N-(cyclopropylmethyl)-5-hydroxy-6-oxo-2-pyrazin-2-yl-1H-pyrimidine-4-carboxamide
Show/Hide
|
C13H13N5O3
|
1
|
| 1 |
EC50 = 3660 nM
|
|
|
|
CP0338858
|
N-[(4-fluorophenyl)methyl]-5-hydroxy-6-oxo-2-pyrazin-2-yl-1H-pyrimidine-4-carboxamide
Show/Hide
|
C16H12FN5O3
|
1
|
| 1 |
EC50 = 3700 nM
|
|
|
|
CP0222790
|
5,6-dihydroxy-2-pyrazin-2-ylpyrimidine-4-carboxylic acid
Show/Hide
|
C9H6N4O4
|
1
|
| 1 |
EC50 = 3800 nM
|
|
|
|
CP0529344
|
N-[(1R)-1-cyclohexylethyl]-5-hydroxy-6-oxo-2-pyrazin-2-yl-1H-pyrimidine-4-carboxamide
Show/Hide
|
C17H21N5O3
|
1
|
| 1 |
EC50 = 4851 nM
|
|
|
|
CP0153974
|
N-benzyl-5-hydroxy-6-oxo-2-pyrazin-2-yl-1H-pyrimidine-4-carboxamide
Show/Hide
|
C16H13N5O3
|
1
|
| 1 |
EC50 = 5410 nM
|
|
|
|
CP0160931
|
5-hydroxy-N-[(1R)-1-(4-methylphenyl)ethyl]-6-oxo-2-pyrazin-2-yl-1H-pyrimidine-4-carboxamide
Show/Hide
|
C18H17N5O3
|
1
|
| 1 |
EC50 = 5520 nM
|
|
|
|
CP0257766
|
5-hydroxy-6-oxo-2-pyridin-2-yl-1H-pyrimidine-4-carboxylic acid
Show/Hide
|
C10H7N3O4
|
1
|
| 1 |
EC50 = 5920 nM
|
|
|
|
CP0711424
|
4-hydroxy-4-(4-methoxyphenyl)-2-oxobut-3-enoic acid
Show/Hide
|
C11H10O5
|
1
|
| 1 |
EC50 = 6700 nM
|
|
|
|
CP0711425
|
4-hydroxy-2-oxo-4-(4-phenylmethoxyphenyl)but-3-enoic acid
Show/Hide
|
C17H14O5
|
1
|
| 1 |
EC50 = 6800 nM
|
|
|
|
CP0711426
|
2-Hydroxy-4-oxo-4-o-tolylbut-2-enoic acid
Show/Hide
|
C11H10O4
|
1
|
| 1 |
EC50 = 6800 nM
|
|
|
|
CP0338859
|
5-hydroxy-6-oxo-N-[(1S)-1-phenylethyl]-2-pyrazin-2-yl-1H-pyrimidine-4-carboxamide
Show/Hide
|
C17H15N5O3
|
1
|
| 1 |
EC50 = 7670 nM
|
|
|
|
CP0655462
|
4-hydroxy-2-oxo-4-(2,4,6-trimethylphenyl)but-3-enoic acid
Show/Hide
|
C13H14O4
|
1
|
| 1 |
EC50 = 8170 nM
|
|
|
|
CP0338856
|
N-cyclohexyl-5-hydroxy-6-oxo-2-pyrazin-2-yl-1H-pyrimidine-4-carboxamide
Show/Hide
|
C15H17N5O3
|
1
|
| 1 |
EC50 = 11480 nM
|
|
|
|
CP0092193
|
5-hydroxy-2-(1-methylimidazol-4-yl)-6-oxo-1H-pyrimidine-4-carboxylic acid
Show/Hide
|
C9H8N4O4
|
1
|
| 1 |
EC50 = 18090 nM
|
|
|
|
CP0338857
|
5-hydroxy-N-[(4-methylphenyl)methyl]-6-oxo-2-pyrazin-2-yl-1H-pyrimidine-4-carboxamide
Show/Hide
|
C17H15N5O3
|
1
|
| 1 |
EC50 = 22600 nM
|
|
|
|
CP0336538
|
5-hydroxy-6-oxo-2-pyrazin-2-yl-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1H-pyrimidine-4-carboxamide
Show/Hide
|
C19H17N5O3
|
1
|
| 1 |
EC50 = 24300 nM
|
|
|
|
CP0339214
|
methyl 5-hydroxy-6-oxo-2-pyrazin-2-yl-1H-pyrimidine-4-carboxylate
Show/Hide
|
C10H8N4O4
|
1
|
| 1 |
EC50 = 25460 nM
|
|
|
|
CP0436403
|
5-hydroxy-N-[(4-methoxyphenyl)methyl]-6-oxo-2-pyrazin-2-yl-1H-pyrimidine-4-carboxamide
Show/Hide
|
C17H15N5O4
|
1
|
| 1 |
EC50 = 35300 nM
|
|
|
|
CP0336536
|
2-(3-acetamidophenyl)-5-hydroxy-6-oxo-1H-pyrimidine-4-carboxylic acid
Show/Hide
|
C13H11N3O5
|
1
|
| 1 |
EC50 = 58900 nM
|
|
|
|
CP0338032
|
5-hydroxy-6-oxo-3,7,13-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,10,12-pentaene-4-carboxylic acid
Show/Hide
|
C11H7N3O4
|
1
|
| 1 |
EC50 = 67400 nM
|
|
|
|
CP0336537
|
methyl 5-hydroxy-2-(1-methylimidazol-4-yl)-6-oxo-1H-pyrimidine-4-carboxylate
Show/Hide
|
C10H10N4O4
|
1
|
| 1 |
EC50 = 71300 nM
|
|
|
|
CP0338854
|
N-butyl-5-hydroxy-6-oxo-2-pyrazin-2-yl-1H-pyrimidine-4-carboxamide
Show/Hide
|
C13H15N5O3
|
1
|
| 1 |
EC50 = 88120 nM
|
|
|
|
CP0477033
|
1-(4-chlorophenyl)-2-[4-[1-(4-chlorophenyl)-4,5-dihydroimidazol-2-yl]phenyl]-4,5-dihydroimidazole
Show/Hide
|
C24H20Cl2N4
|
1
|
| 1 |
IC50 = 5000 nM
|
|
|
|
CP0076946
|
(alpha-methyl-1-adamantyl)methylamine
Show/Hide
|
C12H21N
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0545298
|
1-(4-fluorophenyl)-2-[4-[1-(4-fluorophenyl)-4,5-dihydroimidazol-2-yl]phenyl]-4,5-dihydroimidazole
Show/Hide
|
C24H20F2N4
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0438845
|
1-(4-methoxyphenyl)-2-[4-[1-(4-methoxyphenyl)-4,5-dihydroimidazol-2-yl]phenyl]-4,5-dihydroimidazole
Show/Hide
|
C26H26N4O2
|
1
|
| 1 |
IC50 = 16000 nM
|
|
|
|
CP0466718
|
2-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-1-phenyl-4,5-dihydroimidazole
Show/Hide
|
C18H18N4
|
1
|
| 1 |
IC50 = 30000 nM
|
|
|
|
CP0423707
|
2-[2-[4-(1-pyridin-2-yl-4,5-dihydroimidazol-2-yl)phenyl]-4,5-dihydroimidazol-1-yl]pyridine
Show/Hide
|
C22H20N6
|
1
|
| 1 |
IC50 = 35000 nM
|
|
|
|
CP0558031
|
2-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-1-(4-methoxyphenyl)-4,5-dihydroimidazole
Show/Hide
|
C19H20N4O
|
1
|
| 1 |
IC50 = 44000 nM
|
|
|
|
CP0420850
|
2-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-1-(4-fluorophenyl)-4,5-dihydroimidazole
Show/Hide
|
C18H17FN4
|
1
|
| 1 |
IC50 = 65000 nM
|
|
|
|
CP0423708
|
3-[2-[4-(1-pyridin-3-yl-4,5-dihydroimidazol-2-yl)phenyl]-4,5-dihydroimidazol-1-yl]pyridine
Show/Hide
|
C22H20N6
|
1
|
| 1 |
IC50 = 68000 nM
|
|
|
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CP0420851
|
1-phenyl-2-[4-(1-phenyl-4,5-dihydroimidazol-2-yl)phenyl]-4,5-dihydroimidazole
Show/Hide
|
C24H22N4
|
1
|
| 1 |
IC50 = 77000 nM
|
|
|
