Brief Information of the Cell Line and Protein
Cell Line ID: CL000028 , PC-12
 Cell Line Info 
Synonyms
PC 12
PC12
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_S979
Protein ID: PT02118 , Neuronal acetylcholine receptor subunit alpha-7
 Protein Info 
Gene Name CHRNA7
Organism Rattus norvegicus, Rat
Protein Classification Ion channel
Uniprot ID Q05941
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000028
 Cell Line Info 
 Protein ID: PT02118
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0045981
 Compound Info 
(S)-3-(Benzo[b]thiophen-2-ylmethoxy)-1-aza-bicyclo[2.2.2]octane
   Show/Hide
C16H19NOS
  1
1
IC50 = 26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0522576
 Compound Info 
3-(Benzo[b]thiophen-2-ylmethoxy)-1-aza-bicyclo[2.2.2]octane
   Show/Hide
C16H19NOS
  1
1
IC50 = 59 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0376642
 Compound Info 
3-Benzo[b]thiophen-2-ylmethyl-1-aza-bicyclo[2.2.2]octane
   Show/Hide
C16H19NS
  1
1
IC50 = 110 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0480725
 Compound Info 
3-(Naphthalen-2-ylmethoxy)-1-aza-bicyclo[2.2.2]octane
   Show/Hide
C18H21NO
  1
1
IC50 = 150 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0516310
 Compound Info 
3-(3-Benzo[b]thiophen-2-yl-propyl)-1-aza-bicyclo[2.2.2]octane
   Show/Hide
C18H23NS
  1
1
IC50 = 370 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0516375
 Compound Info 
(R)-3-(Benzo[b]thiophen-2-ylmethoxy)-1-aza-bicyclo[2.2.2]octane
   Show/Hide
C16H19NOS
  1
1
IC50 = 515 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0497084
 Compound Info 
3-(Naphthalen-1-ylmethoxy)-1-aza-bicyclo[2.2.2]octane
   Show/Hide
C18H21NO
  1
1
IC50 = 730 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0404335
 Compound Info 
3-(2,4-Dimethoxy-benzyl)-[2,3']bipyridinyl
   Show/Hide
C19H18N2O2
  1
1
IC50 = 760 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0509680
 Compound Info 
(1-Aza-bicyclo[2.2.2]oct-3-yl)-benzo[b]thiophen-2-yl-methanone
   Show/Hide
C16H17NOS
  1
1
IC50 = 950 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0383942
 Compound Info 
3-(1-Aza-bicyclo[2.2.2]oct-3-yl)-1-benzo[b]thiophen-2-yl-propan-1-one
   Show/Hide
C18H21NOS
  1
1
IC50 = 1700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0431148
 Compound Info 
Benzoclidine
   Show/Hide
C14H17NO2
  1
1
IC50 = 2600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0516308
 Compound Info 
3-Benzyloxy-1-aza-bicyclo[2.2.2]octane
   Show/Hide
C14H19NO
  1
1
IC50 = 3700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS