Brief Information of the Cell Line and Protein
Cell Line ID: CL000027 , tsA201
Synonyms
tsA-201
HEK293-TSA
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_2737
Protein ID: PT01846 , Neuronal acetylcholine receptor subunit alpha-7
Gene Name CHRNA7
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID P36544
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000027  Protein ID: PT01846
 
Compound ID Compound Name Compound Formula
CP0000324
2-acetoxyethyl(trimethyl)ammonium;bromide
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C7H16NO2+
 1
1
EC50 = 4000 nM
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CP0634165
(1S,9R,18R,19S,21R,22R,23R,25R,32S,34R,35R,36S)-15,31-dimethyl-24-phenyl-10,26-dioxa-8,15,24,31-tetraazaundecacyclo[29.5.2.0^{1,32}.0^{2,7}.0^{8,36}.0^{9,22}.0^{13,21}.0^{15,19}.0^{18,23}.0^{25,35}.0^{29,34}]octatriaconta-2,4,6,12,28-pentaene-15,31-diium diiodide
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C40H48I2N4O2
 1
1
IC50 = 1513.56 nM
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CP0633630
(1S,9R,18R,19S,21R,22R,23R,25R,32S,34R,35R,36S)-15,31-bis(cyclohex-2-en-1-yl)-24-phenyl-10,26-dioxa-8,15,24,31-tetraazaundecacyclo[29.5.2.0^{1,32}.0^{2,7}.0^{8,36}.0^{9,22}.0^{13,21}.0^{15,19}.0^{18,23}.0^{25,35}.0^{29,34}]octatriaconta-2,4,6,12,28-pentaene-15,31-bis(ylium) dibromide
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C50H60Br2N4O2
 1
1
IC50 = 2951.21 nM
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CP0006741
4-[1-(1-azabicyclo[2.2.2]octan-3-yl)triazol-4-yl]phenol
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C15H18N4O
 1
1
Ki = 81 nM
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CP0633848
(1S,9R,18R,19S,21R,22R,23R,25R,32S,34R,35R,36S)-15,31-bis[(2E)-but-2-en-1-yl]-24-phenyl-10,26-dioxa-8,15,24,31-tetraazaundecacyclo[29.5.2.0^{1,32}.0^{2,7}.0^{8,36}.0^{9,22}.0^{13,21}.0^{15,19}.0^{18,23}.0^{25,35}.0^{29,34}]octatriaconta-2,4,6,12,28-pentaene-15,31-diium dibromide
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C46H56Br2N4O2
 1
1
Ki = 100 nM
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CP0001237
(1R,9R,18S,19S,21R,22R,23R,25R,32S,34R,35R,36S)-24-phenyl-10,26-dioxa-8,15,24,31-tetraazaundecacyclo[29.5.2.0^{1,32}.0^{2,7}.0^{8,36}.0^{9,22}.0^{13,21}.0^{15,19}.0^{18,23}.0^{25,35}.0^{29,34}]octatriaconta-2,4,6,12,28-pentaene
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C38H42N4O2
 1
1
Ki = 1000 nM
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