| Compound ID |
Compound Name |
Compound Formula |
|
CP0385417
|
[4-(1,3-benzoxazol-2-yl)piperazin-1-yl]-[(1S,2S,4R)-4-[[1-(4-methoxyphenyl)cyclobutyl]amino]-2-thiophen-3-ylcyclohexyl]methanone
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|
C33H38N4O3S
|
2
|
| 1 |
IC50 = 4.2 nM
|
|
|
| 2 |
IC50 = 40 nM
|
|
|
|
CP0387995
|
[4-(1H-benzimidazol-2-yl)piperazin-1-yl]-[(1S,2S,4R)-4-[[1-(4-methoxyphenyl)cyclobutyl]amino]-2-thiophen-3-ylcyclohexyl]methanone
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|
C33H39N5O2S
|
2
|
| 1 |
IC50 = 5.9 nM
|
|
|
| 2 |
IC50 = 11 nM
|
|
|
|
CP0439844
|
[(1S,2S,4R)-4-[[1-(4-methoxyphenyl)cyclobutyl]amino]-2-thiophen-3-ylcyclohexyl]-[4-(5-methyl-1,3-benzoxazol-2-yl)piperazin-1-yl]methanone
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|
C34H40N4O3S
|
2
|
| 1 |
IC50 = 6 nM
|
|
|
| 2 |
IC50 = 70 nM
|
|
|
|
CP0385415
|
[4-(5-bromo-1,3,4-thiadiazol-2-yl)piperazin-1-yl]-[(1S,2S,4R)-4-[[1-(4-methoxyphenyl)cyclobutyl]amino]-2-thiophen-3-ylcyclohexyl]methanone
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|
C28H34BrN5O2S2
|
2
|
| 1 |
IC50 = 18 nM
|
|
|
| 2 |
IC50 = 197 nM
|
|
|
|
CP0496008
|
[4-(1,3-benzoxazol-2-yl)piperazin-1-yl]-[(1S,2S,4R)-4-[2-(4-methoxyphenyl)propan-2-ylamino]-2-thiophen-3-ylcyclohexyl]methanone
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|
C32H38N4O3S
|
2
|
| 1 |
IC50 = 21 nM
|
|
|
| 2 |
IC50 = 110 nM
|
|
|
|
CP0385416
|
[4-(1H-benzimidazol-2-yl)piperazin-1-yl]-[(1S,2S,4R)-4-[2-(4-methoxyphenyl)propan-2-ylamino]-2-thiophen-3-ylcyclohexyl]methanone
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|
C32H39N5O2S
|
2
|
| 1 |
IC50 = 35 nM
|
|
|
| 2 |
IC50 = 39 nM
|
|
|
|
CP0385430
|
[(1S,2S,4R)-4-[[1-(4-methoxyphenyl)cyclobutyl]amino]-2-thiophen-3-ylcyclohexyl]-[4-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperazin-1-yl]methanone
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|
C29H34F3N5O2S2
|
2
|
| 1 |
IC50 = 95 nM
|
|
|
| 2 |
IC50 = 342 nM
|
|
|
|
CP0427428
|
[4-(5-chloropyridin-2-yl)piperazin-1-yl]-[(1S,2S,4R)-4-[[(1R)-1-(4-methoxyphenyl)ethyl]amino]-2-thiophen-3-ylcyclohexyl]methanone
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|
C29H35ClN4O2S
|
2
|
| 1 |
IC50 = 324 nM
|
|
|
| 2 |
IC50 = 1925 nM
|
|
|
