Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT05756 , Leukotriene B4 receptor 2
Gene Name LTB4R2
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q9NPC1
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026  Protein ID: PT05756
 
Compound ID Compound Name Compound Formula
CP0486154
4-fluoro-2-[4-[(N-pentanoylanilino)methyl]phenyl]benzoic acid
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C25H24FNO3
 1
1
EC50 = 22.1 nM
   TI
   LI
   LO
   TS
CP0466285
N-phenyl-N-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]pentanamide
   Show/Hide
C25H25N5O
 1
1
EC50 = 23.2 nM
   TI
   LI
   LO
   TS
CP0487537
N-(4-fluorophenyl)-N-[[4-[5-fluoro-2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-3-methylbutanamide
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C25H23F2N5O
 1
1
EC50 = 25 nM
   TI
   LI
   LO
   TS
CP0466287
2-[4-[(4-methyl-N-pentanoylanilino)methyl]phenyl]benzoic acid
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C26H27NO3
 1
1
EC50 = 26 nM
   TI
   LI
   LO
   TS
CP0517356
2-[4-[(4-fluoro-N-pentanoylanilino)methyl]phenyl]benzoic acid
   Show/Hide
C25H24FNO3
 1
1
EC50 = 27.3 nM
   TI
   LI
   LO
   TS
CP0548825
2-[4-[(N-pentanoylanilino)methyl]phenyl]benzoic acid
   Show/Hide
C25H25NO3
 1
1
EC50 = 28.9 nM
   TI
   LI
   LO
   TS
CP0466286
2-[4-[[N-(3-methylbutanoyl)anilino]methyl]phenyl]benzoic acid
   Show/Hide
C25H25NO3
 1
1
EC50 = 36.3 nM
   TI
   LI
   LO
   TS
CP0551684
2-[4-[(N-(2-phenylacetyl)anilino)methyl]phenyl]benzoic acid
   Show/Hide
C28H23NO3
 1
1
EC50 = 38.3 nM
   TI
   LI
   LO
   TS
CP0517358
2-[4-[(N-butanoylanilino)methyl]phenyl]benzoic acid
   Show/Hide
C24H23NO3
 1
1
EC50 = 42.2 nM
   TI
   LI
   LO
   TS
CP0486141
2-[4-[(4-chloro-N-pentanoylanilino)methyl]phenyl]benzoic acid
   Show/Hide
C25H24ClNO3
 1
1
EC50 = 47.5 nM
   TI
   LI
   LO
   TS
CP0486146
N-[[4-[2-(5-oxo-4H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]-N-phenylpentanamide
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C26H25N3O3
 1
1
EC50 = 48.2 nM
   TI
   LI
   LO
   TS
CP0554586
2-[3-fluoro-4-[(N-pentanoylanilino)methyl]phenyl]benzoic acid
   Show/Hide
C25H24FNO3
 1
1
EC50 = 48.4 nM
   TI
   LI
   LO
   TS
CP0517342
2-[4-[(3,4-difluoro-N-pentanoylanilino)methyl]phenyl]benzoic acid
   Show/Hide
C25H23F2NO3
 1
1
EC50 = 48.8 nM
   TI
   LI
   LO
   TS
CP0486152
2-[4-[(3-fluoro-N-pentanoylanilino)methyl]phenyl]benzoic acid
   Show/Hide
C25H24FNO3
 1
1
EC50 = 51.8 nM
   TI
   LI
   LO
   TS
CP0486151
2-[4-[(N-benzoylanilino)methyl]phenyl]benzoic acid
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C27H21NO3
 1
1
EC50 = 52 nM
   TI
   LI
   LO
   TS
CP0548138
5-fluoro-2-[4-[(N-pentanoylanilino)methyl]phenyl]benzoic acid
   Show/Hide
C25H24FNO3
 1
1
EC50 = 60.7 nM
   TI
   LI
   LO
   TS
CP0870106
1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-isopropyl-4-methyl-1H-imidazol-5(4H)-one
   Show/Hide
C25H30N6O
 1
1
EC50 = 67.6 nM
   TI
   LI
   LO
   TS
CP0571836
2-[4-[(4-hydroxy-N-pentanoylanilino)methyl]phenyl]benzoic acid
   Show/Hide
C25H25NO4
 1
1
EC50 = 75 nM
   TI
   LI
   LO
   TS
CP0486153
2-[4-[[N-(butylcarbamoyl)anilino]methyl]phenyl]benzoic acid
   Show/Hide
C25H26N2O3
 1
1
EC50 = 96 nM
   TI
   LI
   LO
   TS
CP0548191
2-[4-[(N-(2-cyclopropylacetyl)anilino)methyl]phenyl]benzoic acid
   Show/Hide
C25H23NO3
 1
1
EC50 = 103 nM
   TI
   LI
   LO
   TS
CP0551686
2-[4-[(4-cyano-N-pentanoylanilino)methyl]phenyl]benzoic acid
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C26H24N2O3
 1
1
EC50 = 134 nM
   TI
   LI
   LO
   TS
CP0487538
2-[4-[[pentanoyl(pyridin-4-yl)amino]methyl]phenyl]benzoic acid
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C24H24N2O3
 1
1
EC50 = 167 nM
   TI
   LI
   LO
   TS
CP0554607
2-[4-[[benzoyl(butyl)amino]methyl]phenyl]benzoic acid
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C25H25NO3
 1
1
EC50 = 216 nM
   TI
   LI
   LO
   TS
CP0486140
2-[4-[(4-methoxy-N-pentanoylanilino)methyl]phenyl]benzoic acid
   Show/Hide
C26H27NO4
 1
1
EC50 = 229 nM
   TI
   LI
   LO
   TS
CP0545781
3-[4-[(N-pentanoylanilino)methyl]phenyl]pyridine-4-carboxylic acid
   Show/Hide
C24H24N2O3
 1
1
EC50 = 357 nM
   TI
   LI
   LO
   TS
CP0486143
2-[4-[(N-propanoylanilino)methyl]phenyl]benzoic acid
   Show/Hide
C23H21NO3
 1
1
EC50 = 390 nM
   TI
   LI
   LO
   TS
CP0551685
2-[4-[[N-(2-methylpropanoyl)anilino]methyl]phenyl]benzoic acid
   Show/Hide
C24H23NO3
 1
1
EC50 = 398 nM
   TI
   LI
   LO
   TS
CP0486149
2-[4-[[butyl(3-phenylpropanoyl)amino]methyl]phenyl]benzoic acid
   Show/Hide
C27H29NO3
 1
1
EC50 = 404 nM
   TI
   LI
   LO
   TS
CP0041261
2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
   Show/Hide
C25H28N6O
 1
1
EC50 = 410 nM
   TI
   LI
   LO
   TS
CP0558006
5-chloro-2-[4-[(N-pentanoylanilino)methyl]phenyl]benzoic acid
   Show/Hide
C25H24ClNO3
 1
1
EC50 = 428 nM
   TI
   LI
   LO
   TS
CP0887676
1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-methyl-4-phenyl-1H-imidazol-5(4H)-one
   Show/Hide
C28H28N6O
 1
1
EC50 = 550 nM
   TI
   LI
   LO
   TS
CP0517357
methyl 2-[4-[(N-pentanoylanilino)methyl]phenyl]benzoate
   Show/Hide
C26H27NO3
 1
1
EC50 = 570 nM
   TI
   LI
   LO
   TS
CP0540411
2-[4-[(pentanoylamino)methyl]phenyl]benzoic acid
   Show/Hide
C19H21NO3
 1
1
EC50 = 658 nM
   TI
   LI
   LO
   TS
CP0564132
2-[4-[(3-chloro-N-pentanoylanilino)methyl]phenyl]benzoic acid
   Show/Hide
C25H24ClNO3
 1
1
EC50 = 720 nM
   TI
   LI
   LO
   TS
CP0517354
2-[4-[[butyl-(2-phenylacetyl)amino]methyl]phenyl]benzoic acid
   Show/Hide
C26H27NO3
 1
1
EC50 = 789 nM
   TI
   LI
   LO
   TS
CP0547232
4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.5]dec-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid
   Show/Hide
C26H30N2O3
 1
1
EC50 = 860 nM
   TI
   LI
   LO
   TS
CP0547228
4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid
   Show/Hide
C25H28N2O3
 1
1
EC50 = 1490 nM
   TI
   LI
   LO
   TS
CP0486145
2-[4-[(N-pentanoylanilino)methyl]phenyl]benzamide
   Show/Hide
C25H26N2O2
 1
1
EC50 = 1730 nM
   TI
   LI
   LO
   TS
CP0486148
N-methylsulfonyl-2-[4-[(N-pentanoylanilino)methyl]phenyl]benzamide
   Show/Hide
C26H28N2O4S
 1
1
EC50 = 2060 nM
   TI
   LI
   LO
   TS
CP0549514
2-[4-[(N-acetylanilino)methyl]phenyl]benzoic acid
   Show/Hide
C22H19NO3
 1
1
EC50 = 2400 nM
   TI
   LI
   LO
   TS
CP0486147
2-[4-[[benzyl(pentanoyl)amino]methyl]phenyl]benzoic acid
   Show/Hide
C26H27NO3
 1
1
EC50 = 2650 nM
   TI
   LI
   LO
   TS
CP0517355
2-[4-[[cyclohexyl(pentanoyl)amino]methyl]phenyl]benzoic acid
   Show/Hide
C25H31NO3
 1
1
EC50 = 2960 nM
   TI
   LI
   LO
   TS
CP0486142
2-[4-[[N-(3-methoxypropanoyl)anilino]methyl]phenyl]benzoic acid
   Show/Hide
C24H23NO4
 1
1
EC50 = 3060 nM
   TI
   LI
   LO
   TS
CP0538751
N-[[4-[2-(hydroxymethyl)phenyl]phenyl]methyl]-N-phenylpentanamide
   Show/Hide
C25H27NO2
 1
1
EC50 = 4260 nM
   TI
   LI
   LO
   TS
CP0887677
3-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-5,5-dimethylimidazolidin-4-one
   Show/Hide
C23H28N6O
 1
1
EC50 = 6390 nM
   TI
   LI
   LO
   TS
CP0549515
2-[4-[[pentanoyl(propan-2-yl)amino]methyl]phenyl]benzoic acid
   Show/Hide
C22H27NO3
 1
1
EC50 = 6460 nM
   TI
   LI
   LO
   TS
CP0451134
4'-(2-Benzyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid
   Show/Hide
C28H26N2O3
 1
1
EC50 = 6580 nM
   TI
   LI
   LO
   TS
CP0870107
(3R,7aR)-2-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-3-butylhexahydro-1H-pyrrolo[1,2-c]imidazol-1-one
   Show/Hide
C24H28N6O
 1
1
EC50 = 7500 nM
   TI
   LI
   LO
   TS
CP0451135
2-butyl-5,5-dimethyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-one
   Show/Hide
C23H26N6O
 1
1
EC50 = 8140 nM
   TI
   LI
   LO
   TS
CP0114119
2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid(CV-11974)
   Show/Hide
C24H20N6O3
 1
1
EC50 = 15000 nM
   TI
   LI
   LO
   TS
CP0041674
(S)-3-Methyl-2-{pentanoyl-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino}-butyric acid
   Show/Hide
C24H29N5O3
 1
1
EC50 = 16000 nM
   TI
   LI
   LO
   TS
CP0471071
4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-ylmethyl)-biphenyl-2-carboxylic acid
   Show/Hide
C25H30N2O3
 1
1
EC50 = 24200 nM
   TI
   LI
   LO
   TS
CP0507541
2-[4-[[methyl(pentanoyl)amino]methyl]phenyl]benzoic acid
   Show/Hide
C20H23NO3
 1
1
EC50 > 7600 nM
   TI
   LI
   LO
   TS