| Compound ID |
Compound Name |
Compound Formula |
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CP0430250
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(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S,5S,8S,11S,15E,20S)-20-[[(2S)-2-[[2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-2-benzyl-5-[(2S)-butan-2-yl]-8-(3-carbamimidamidopropyl)-11,20-dimethyl-3,6,9,21-tetraoxo-1,4,7,10-tetrazacyclohenicos-15-ene-11-carbonyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
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C99H152N28O24
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3
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| 1 |
EC50 = 0.1202 nM
|
|
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| 2 |
EC50 = 3.311 nM
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|
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| 3 |
Ki = 275.42 nM
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CP0542595
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2-[2-(4-cyanophenyl)ethyl]-1-[(E)-(7-ethyl-5-methoxy-1H-indol-3-yl)methylideneamino]guanidine
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C22H24N6O
|
2
|
| 1 |
EC50 = 1.4 nM
|
|
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| 2 |
EC50 = 10.2 nM
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CP0562498
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1-[(E)-(5-cyano-7-ethyl-1H-indol-3-yl)methylideneamino]-2-(2-pyridin-3-ylethyl)guanidine
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C20H21N7
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
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CP0562501
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1-[(E)-(7-ethyl-5-methoxy-1H-indol-3-yl)methylideneamino]-2-(2-pyridin-3-ylethyl)guanidine
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C20H24N6O
|
1
|
| 1 |
EC50 = 2.3 nM
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|
|
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CP0559440
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methyl 4-[2-[[amino-[(2E)-2-[(5-cyano-7-methyl-1H-indol-3-yl)methylidene]hydrazinyl]methylidene]amino]ethyl]benzoate
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C22H22N6O2
|
3
|
| 1 |
EC50 = 3.1 nM
|
|
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| 2 |
EC50 = 12.3 nM
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|
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| 3 |
Ki = 68.7 nM
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CP0430247
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(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S,5S,8S,11S,15E,20S)-20-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-2-benzyl-5-[(2S)-butan-2-yl]-8-(3-carbamimidamidopropyl)-11,20-dimethyl-3,6,9,21-tetraoxo-1,4,7,10-tetrazacyclohenicos-15-ene-11-carbonyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
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C109H173N33O25
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2
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| 1 |
EC50 = 3.548 nM
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|
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| 2 |
Ki = 109.65 nM
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CP0962324
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(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,37S,40S,43R,48R,51S,54S,57S,60S,63S,66S,69S,72S,75S,81R)-81-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-3-amino-3-oxopropoxy]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamidopentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-43-amino-25,40-bis(4-aminobutyl)-54,69-dibenzyl-16,57,66-tris[(2S)-butan-2-yl]-48-[[2-[[2-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]carbamoyl]-63,75-bis(3-carbamimidamidopropyl)-19,72-bis(2-carboxyethyl)-51-[(1R)-1-hydroxyethyl]-10,13,22,28-tetrakis(hydroxymethyl)-37-(1H-indol-3-ylmethyl)-31-methyl-7-(2-methylpropyl)-6,9,12,15,18,21,24,27,30,33,36,39,42,50,53,56,59,62,65,68,71,74,77,80-tetracosaoxo-60-propan-2-yl-1,2,45,46-tetrathia-5,8,11,14,17,20,23,26,29,32,35,38,41,49,52,55,58,61,64,67,70,73,76,79-tetracosazacyclodooctacontane-4-carboxylic acid
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C212H324N62O57S4
|
2
|
| 1 |
EC50 = 4.365 nM
|
|
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| 2 |
Ki = 186.21 nM
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CP0430248
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(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S,5S,8S,11S,15E,20S)-20-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-methylbutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-2-benzyl-5-[(2S)-butan-2-yl]-8-(3-carbamimidamidopropyl)-11,20-dimethyl-3,6,9,21-tetraoxo-1,4,7,10-tetrazacyclohenicos-15-ene-11-carbonyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
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C116H185N35O27
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2
|
| 1 |
EC50 = 4.467 nM
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|
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| 2 |
Ki = 93.33 nM
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CP0463564
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(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S,5S,8S,11S,15E,20S)-20-[[(2S)-2-[[2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-2-benzyl-5-[(2S)-butan-2-yl]-8-(3-carbamimidamidopropyl)-11,20-dimethyl-3,6,9,21-tetraoxo-1,4,7,10-tetrazacyclohenicos-15-ene-11-carbonyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
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|
C97H150N28O23
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2
|
| 1 |
EC50 = 4.467 nM
|
|
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| 2 |
Ki = 151.36 nM
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CP0463567
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(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S,5S,8S,11S,15E,20S)-20-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-2-benzyl-5-[(2S)-butan-2-yl]-8-(3-carbamimidamidopropyl)-11,20-dimethyl-3,6,9,21-tetraoxo-1,4,7,10-tetrazacyclohenicos-15-ene-11-carbonyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
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C111H175N33O26
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2
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| 1 |
EC50 = 5.248 nM
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|
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| 2 |
Ki = 107.15 nM
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CP0573210
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1-[(E)-(7-ethyl-5-methoxy-1H-indol-3-yl)methylideneamino]-2-[2-(4-fluorophenyl)ethyl]guanidine
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C21H24FN5O
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1
|
| 1 |
EC50 = 5.6 nM
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|
|
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CP0959505
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3,3'-((4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,37S,40S,43R,48R,51S,54S,57S,60S,63S,66S,69S,72S,75S,81R)-37-((1H-indol-3-yl)methyl)-43-amino-48-((6S,9S)-1-amino-6-((S)-1-carboxy-2-(1H-indol-3-yl)ethylcarbamoyl)-9-(hydroxymethyl)-1-imino-8,11,14-trioxo-2,7,10,13-tetraazapentadecan-15-ylcarbamoyl)-25,40-bis(4-aminobutyl)-54,69-dibenzyl-16,57,66-tri-sec-butyl-4-carboxy-81-((3S,9S,12S,15S)-1-((S)-1-((S)-2-((S)-2-((S)-2-((S)-1-carboxy-2-(1H-indol-3-yl)ethylamino)-5-guanidinopentanamido)propanamido)propanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-3-(4-hydroxybenzyl)-15-isobutyl-9-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecanamido)-63,75-bis(3-guanidinopropyl)-51-((R)-1-hydroxyethyl)-10,13,22,28-tetrakis(hydroxymethyl)-7-isobutyl-60-isopropyl-31-methyl-6,9,12,15,18,21,24,27,30,33,36,39,42,50,53,56,59,62,65,68,71,74,77,80-tetracosaoxo-1,2,45,46-tetrathia-5,8,11,14,17,20,23,26,29,32,35,38,41,49,52,55,58,61,64,67,70,73,76,79-tetracosaazacyclodooctacontane-19,72-diyl)dipropanoic acid
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C207H316N60O55S4
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2
|
| 1 |
EC50 = 6.166 nM
|
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| 2 |
Ki = 45.71 nM
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CP0959506
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(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,37S,40S,43R,48R,51S,54S,57S,60S,63S,66S,69S,72S,75S,81R)-43-amino-25,40-bis(4-aminobutyl)-54,69-dibenzyl-16,57,66-tris[(2S)-butan-2-yl]-81-[[(2S)-2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-5-carbamimidamido-2-[[(2S)-1-carbamoyloxy-3-(1H-indol-3-yl)propan-2-yl]amino]pentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-48-[[2-[[2-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]carbamoyl]-63,75-bis(3-carbamimidamidopropyl)-19,72-bis(2-carboxyethyl)-51-[(1R)-1-hydroxyethyl]-10,13,22,28-tetrakis(hydroxymethyl)-37-(1H-indol-3-ylmethyl)-31-methyl-7-(2-methylpropyl)-6,9,12,15,18,21,24,27,30,33,36,39,42,50,53,56,59,62,65,68,71,74,77,80-tetracosaoxo-60-propan-2-yl-1,2,45,46-tetrathia-5,8,11,14,17,20,23,26,29,32,35,38,41,49,52,55,58,61,64,67,70,73,76,79-tetracosazacyclodooctacontane-4-carboxylic acid
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C208H319N61O55S4
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2
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| 1 |
EC50 = 6.166 nM
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| 2 |
Ki = 109.65 nM
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CP0562497
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methyl 4-[2-[[amino-[(2E)-2-[(5-methoxy-7-methyl-1H-indol-3-yl)methylidene]hydrazinyl]methylidene]amino]ethyl]benzoate
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|
C22H25N5O3
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1
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| 1 |
EC50 = 7.7 nM
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|
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CP0551158
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1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]-2-(2-pyridin-3-ylethyl)guanidine
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C19H22N6O
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1
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| 1 |
EC50 = 11 nM
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CP0482927
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(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S,5S,8S,11S,15E,20S)-20-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-acetamidoacetyl)amino]-3-methylbutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-2-benzyl-5-[(2S)-butan-2-yl]-8-(3-carbamimidamidopropyl)-11,20-dimethyl-3,6,9,21-tetraoxo-1,4,7,10-tetrazacyclohenicos-15-ene-11-carbonyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
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|
C118H187N35O28
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2
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| 1 |
EC50 = 11.75 nM
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| 2 |
Ki = 229.09 nM
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CP0955896
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(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,37S,40S,43R,48R,51S,54S,57S,60S,63S,66S,69S,72S,75S,81R)-43-amino-25,40-bis(4-aminobutyl)-54,69-dibenzyl-16,57,66-tris[(2S)-butan-2-yl]-81-[[(2S)-2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-5-carbamimidamido-2-[[(2S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl]amino]pentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-48-[[2-[[2-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]carbamoyl]-63,75-bis(3-carbamimidamidopropyl)-19,72-bis(2-carboxyethyl)-51-[(1R)-1-hydroxyethyl]-10,13,22,28-tetrakis(hydroxymethyl)-37-(1H-indol-3-ylmethyl)-31-methyl-7-(2-methylpropyl)-6,9,12,15,18,21,24,27,30,33,36,39,42,50,53,56,59,62,65,68,71,74,77,80-tetracosaoxo-60-propan-2-yl-1,2,45,46-tetrathia-5,8,11,14,17,20,23,26,29,32,35,38,41,49,52,55,58,61,64,67,70,73,76,79-tetracosazacyclodooctacontane-4-carboxylic acid
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C207H318N60O54S4
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2
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| 1 |
EC50 = 13.18 nM
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| 2 |
Ki = 331.13 nM
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CP0574596
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2-[2-(4-cyanophenyl)ethyl]-1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]guanidine
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C21H22N6O
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2
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| 1 |
EC50 = 13.2 nM
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| 2 |
Ki = 268 nM
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CP0573469
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1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]-2-[2-(4-nitrophenyl)ethyl]guanidine
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C20H22N6O3
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1
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| 1 |
EC50 = 13.6 nM
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CP0958721
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(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,37S,40S,43R,48R,51S,54S,57S,60S,63S,66S,69S,72S,75S,81R)-43-amino-25,40-bis(4-aminobutyl)-81-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamidopentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-54,69-dibenzyl-16,57,66-tris[(2S)-butan-2-yl]-48-[[2-[[2-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]carbamoyl]-63,75-bis(3-carbamimidamidopropyl)-19,72-bis(2-carboxyethyl)-51-[(1R)-1-hydroxyethyl]-10,13,22,28-tetrakis(hydroxymethyl)-37-(1H-indol-3-ylmethyl)-31-methyl-7-(2-methylpropyl)-6,9,12,15,18,21,24,27,30,33,36,39,42,50,53,56,59,62,65,68,71,74,77,80-tetracosaoxo-60-propan-2-yl-1,2,45,46-tetrathia-5,8,11,14,17,20,23,26,29,32,35,38,41,49,52,55,58,61,64,67,70,73,76,79-tetracosazacyclodooctacontane-4-carboxylic acid
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C207H317N61O54S4
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2
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| 1 |
EC50 = 15.85 nM
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| 2 |
Ki = 190.55 nM
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CP0384417
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(7-ethyl-5-hydroxy-1H-indol-3-yl)methylideneamino]guanidine
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C20H22ClN5O
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3
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| 1 |
EC50 = 18.2 nM
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| 2 |
EC50 = 22 nM
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| 3 |
Ki = 274 nM
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CP0546059
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(7-ethyl-5-methoxy-1H-indol-3-yl)methylideneamino]guanidine
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C21H24ClN5O
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1
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| 1 |
EC50 = 19.5 nM
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CP0562489
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2-[2-(4-fluorophenyl)ethyl]-1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]guanidine
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C20H22FN5O
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1
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| 1 |
EC50 = 52.2 nM
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CP0559439
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1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]-2-(2-thiophen-3-ylethyl)guanidine
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C18H21N5OS
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1
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| 1 |
EC50 = 53 nM
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CP0546057
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1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]-2-[2-(4-methoxyphenyl)ethyl]guanidine
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C21H25N5O2
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1
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| 1 |
EC50 = 56.1 nM
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CP0562494
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2-[2-(4-iodophenyl)ethyl]-1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]guanidine
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C20H22IN5O
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1
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| 1 |
EC50 = 67 nM
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CP0562493
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2-[2-(4-bromophenyl)ethyl]-1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]guanidine
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C20H22BrN5O
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1
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| 1 |
EC50 = 69.9 nM
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CP0578042
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1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]-2-(2-thiophen-2-ylethyl)guanidine
Show/Hide
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C18H21N5OS
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1
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| 1 |
EC50 = 73 nM
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CP0467965
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]guanidine
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C20H22ClN5O
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1
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| 1 |
EC50 = 74.7 nM
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CP0559438
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(5-cyano-7-methyl-1H-indol-3-yl)methylideneamino]guanidine
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C20H19ClN6
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1
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| 1 |
EC50 = 82.3 nM
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CP0542594
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2-[2-[4-(dimethylamino)phenyl]ethyl]-1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]guanidine
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C22H28N6O
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1
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| 1 |
EC50 = 98.4 nM
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CP0573153
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1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]-2-(2-phenylethyl)guanidine
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C20H23N5O
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1
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| 1 |
EC50 = 224 nM
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CP0573466
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1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]-2-[2-(4-methylphenyl)ethyl]guanidine
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C21H25N5O
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1
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| 1 |
EC50 = 238 nM
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CP0579278
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(5-cyano-1H-indol-3-yl)methylideneamino]guanidine
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C19H17ClN6
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1
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| 1 |
EC50 = 253 nM
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CP0562500
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1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]-2-(2-pyridin-4-ylethyl)guanidine
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C19H22N6O
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1
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| 1 |
EC50 = 273 nM
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CP0459463
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2-[2-(3,4-dichlorophenyl)ethyl]-1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]guanidine
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C20H21Cl2N5O
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3
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| 1 |
EC50 = 306 nM
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| 2 |
EC50 = 2700 nM
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| 3 |
Ki = 2505 nM
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CP0562487
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methyl 3-[(E)-[[N'-[2-(4-chlorophenyl)ethyl]carbamimidoyl]hydrazinylidene]methyl]-1H-indole-5-carboxylate
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C20H20ClN5O2
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1
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| 1 |
EC50 = 312 nM
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CP0573152
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(5-nitro-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C18H17ClN6O2
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1
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| 1 |
EC50 = 317 nM
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CP0546056
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(7-methyl-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C19H20ClN5
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1
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| 1 |
EC50 = 647 nM
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CP0573150
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2-[2-(2-chlorophenyl)ethyl]-1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C20H22ClN5O
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1
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| 1 |
EC50 = 797 nM
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CP0562495
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1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]-2-(2-pyridin-2-ylethyl)guanidine
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C19H22N6O
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1
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| 1 |
EC50 = 855 nM
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CP0460635
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(4S)-4-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-3-sulfanylpropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-5-carbamimidamido-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2R)-1-[[2-[[2-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid
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C136H213N43O33S2
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2
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| 1 |
EC50 = 1174.9 nM
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| 2 |
Ki = 2951.21 nM
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CP0562492
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2-[2-(3-chlorophenyl)ethyl]-1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C20H22ClN5O
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1
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| 1 |
EC50 = 1275 nM
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CP0573468
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(5-fluoro-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C18H17ClFN5
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1
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| 1 |
EC50 = 1355 nM
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CP0573465
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2-[3-(4-chlorophenyl)propyl]-1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C21H24ClN5O
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1
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| 1 |
EC50 = 1661 nM
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CP0576844
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(5-methoxy-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C19H20ClN5O
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1
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| 1 |
EC50 = 1677 nM
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CP0559441
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(7-fluoro-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C18H17ClFN5
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1
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| 1 |
EC50 = 2788 nM
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CP0546058
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1-[(E)-(5-chloro-1H-indol-3-yl)methylideneamino]-2-[2-(4-chlorophenyl)ethyl]guanidine
Show/Hide
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C18H17Cl2N5
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1
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| 1 |
EC50 = 2819 nM
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CP0562491
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2-(4-chlorophenyl)-1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C18H18ClN5O
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1
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| 1 |
EC50 = 3121 nM
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CP0573467
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(4-fluoro-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C18H17ClFN5
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1
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| 1 |
EC50 = 3208 nM
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CP0573204
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(6-fluoro-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C18H17ClFN5
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1
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| 1 |
EC50 = 3466 nM
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CP0576668
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2-[(4-chlorophenyl)methyl]-1-[(E)-(5-methoxy-7-methyl-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C19H20ClN5O
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1
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| 1 |
EC50 = 3947 nM
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CP0460632
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(4S)-4-[[(2S)-2-[[2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid
Show/Hide
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C96H149N29O26
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1
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| 1 |
EC50 = 4570.88 nM
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CP0575787
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(6-methoxy-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C19H20ClN5O
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1
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| 1 |
EC50 = 4745 nM
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CP0537716
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(7-methoxy-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C19H20ClN5O
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1
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| 1 |
EC50 = 4952 nM
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CP0562490
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1-[(E)-(5-bromo-1H-indol-3-yl)methylideneamino]-2-[2-(4-chlorophenyl)ethyl]guanidine
Show/Hide
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C18H17BrClN5
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1
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| 1 |
EC50 = 5236 nM
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CP0562433
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-1H-indol-3-ylmethylideneamino]guanidine
Show/Hide
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C18H18ClN5
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1
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| 1 |
EC50 = 6937 nM
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CP0573203
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(6-methyl-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C19H20ClN5
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1
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| 1 |
EC50 = 7436 nM
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CP0573464
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-1-(5-methoxy-1H-indol-3-yl)ethylideneamino]guanidine
Show/Hide
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C20H22ClN5O
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1
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| 1 |
EC50 = 7686 nM
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CP0463568
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(4S)-4-[[(2S)-2-[[2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-5-carbamimidamido-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid
Show/Hide
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C93H142N28O26
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1
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| 1 |
EC50 = 8709.64 nM
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CP0460634
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(4S)-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(3S,6S,9S,12S,16Z,21S)-3-benzyl-6-[(2S)-butan-2-yl]-21-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]carbamoyl]-12,21-dimethyl-2,5,8,11-tetraoxo-9-propan-2-yl-1,4,7,10-tetrazacyclohenicos-16-en-12-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid
Show/Hide
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C110H173N33O26
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
Ki = 575.44 nM
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CP0460641
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(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(5S,8S,11S,14S,17S)-17-[[(2S)-2-[[2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-14-benzyl-11-[(2S)-butan-2-yl]-8-(3-carbamimidamidopropyl)-7,10,13,16-tetraoxo-1,2-dithia-6,9,12,15-tetrazacyclononadecane-5-carbonyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
Show/Hide
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C93H142N28O24S2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
Ki = 2511.89 nM
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CP0463565
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(4S)-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(3S,6S,9S,12S,16Z,21S)-3-benzyl-6-[(2S)-butan-2-yl]-21-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]carbamoyl]-12,21-dimethyl-2,5,8,11-tetraoxo-9-propan-2-yl-1,4,7,10-tetrazacyclohenicos-16-en-12-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid
Show/Hide
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C112H175N33O27
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
Ki = 602.56 nM
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CP0542593
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(4-methyl-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C19H20ClN5
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1
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| 1 |
EC50 > 10000 nM
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CP0551156
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(5-iodo-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C18H17ClIN5
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1
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| 1 |
EC50 > 10000 nM
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CP0559348
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2-[2-(4-chlorophenyl)ethyl]-1-[(E)-(5-methyl-1H-indol-3-yl)methylideneamino]guanidine
Show/Hide
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C19H20ClN5
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1
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| 1 |
EC50 > 10000 nM
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CP0482692
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(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S,5S,8S,11S,20S)-20-[[(2S)-2-[[2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-2-benzyl-5-[(2S)-butan-2-yl]-8-(3-carbamimidamidopropyl)-3,6,9,17,21-pentaoxo-1,4,7,10,16-pentazacyclohenicosane-11-carbonyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
Show/Hide
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C96H147N29O25
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1
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| 1 |
EC50 > 1000 nM
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CP0416446
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(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,37S,40S,43R,48R,54S,57S,60S,63S,66S,69S,72S,75S,78S,81S,84R)-43-amino-48-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-methylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-25,40-bis(4-aminobutyl)-60,78-dibenzyl-16,63,75-tris[(2S)-butan-2-yl]-19,57-bis(2-carboxyethyl)-84-[[2-[[2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]carbamoyl]-54,66-bis[3-(diaminomethylideneamino)propyl]-81-[(1R)-1-hydroxyethyl]-10,13,22,28-tetrakis(hydroxymethyl)-37-(1H-indol-3-ylmethyl)-31,69-dimethyl-7-(2-methylpropyl)-6,9,12,15,18,21,24,27,30,33,36,39,42,49,52,55,58,61,64,67,70,73,76,79,82-pentacosaoxo-72-propan-2-yl-1,2,45,46-tetrathia-5,8,11,14,17,20,23,26,29,32,35,38,41,50,53,56,59,62,65,68,71,74,77,80,83-pentacosazacyclopentaoctacontane-4-carboxylic acid
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C173H274N52O48S4
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2
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| 1 |
IC50 = 4.266 nM
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| 2 |
Ki = 112.2 nM
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CP0424401
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(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,37S,40S,43R,48R,54S,57S,60S,63S,66S,69S,72S,75S,78S,81S,84R)-43-amino-25,40-bis(4-aminobutyl)-48-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-60,78-dibenzyl-16,63,75-tris[(2S)-butan-2-yl]-19,57-bis(2-carboxyethyl)-84-[[2-[[2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]carbamoyl]-54,66-bis[3-(diaminomethylideneamino)propyl]-81-[(1R)-1-hydroxyethyl]-10,13,22,28-tetrakis(hydroxymethyl)-37-(1H-indol-3-ylmethyl)-31,69-dimethyl-7-(2-methylpropyl)-6,9,12,15,18,21,24,27,30,33,36,39,42,49,52,55,58,61,64,67,70,73,76,79,82-pentacosaoxo-72-propan-2-yl-1,2,45,46-tetrathia-5,8,11,14,17,20,23,26,29,32,35,38,41,50,53,56,59,62,65,68,71,74,77,80,83-pentacosazacyclopentaoctacontane-4-carboxylic acid
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C166H262N50O46S4
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2
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| 1 |
IC50 = 5.129 nM
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| 2 |
Ki = 112.2 nM
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CP0378163
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(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,37S,40S,43R,48R,54S,57S,60S,63S,66S,69S,72S,75S,78S,81S,84R)-43,48-diamino-25,40-bis(4-aminobutyl)-60,78-dibenzyl-16,63,75-tris[(2S)-butan-2-yl]-84-[[2-[[2-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]carbamoyl]-54,66-bis(3-carbamimidamidopropyl)-19,57-bis(2-carboxyethyl)-81-[(1R)-1-hydroxyethyl]-10,13,22,28-tetrakis(hydroxymethyl)-37-(1H-indol-3-ylmethyl)-31,69-dimethyl-7-(2-methylpropyl)-6,9,12,15,18,21,24,27,30,33,36,39,42,49,52,55,58,61,64,67,70,73,76,79,82-pentacosaoxo-72-propan-2-yl-1,2,45,46-tetrathia-5,8,11,14,17,20,23,26,29,32,35,38,41,50,53,56,59,62,65,68,71,74,77,80,83-pentacosazacyclopentaoctacontane-4-carboxylic acid
Show/Hide
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C154H239N45O44S4
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2
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| 1 |
IC50 = 12.59 nM
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| 2 |
Ki = 109.65 nM
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CP0570216
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(4S)-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoic acid
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C118H193N39O29
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2
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| 1 |
IC50 = 504 nM
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| 2 |
IC50 = 7820 nM
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CP0544863
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N-[4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxo-1-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
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C25H20ClN5O3
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2
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| 1 |
IC50 = 561 nM
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| 2 |
IC50 = 3040 nM
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CP0578526
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5-oxo-1-(pyridin-3-ylmethyl)-N-[4-[3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]phenyl]pyrrolidine-3-carboxamide
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C26H20F3N5O3
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1
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| 1 |
IC50 = 1490 nM
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CP0569787
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N-[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxo-1-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
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C26H23N5O3
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1
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| 1 |
IC50 = 2120 nM
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CP0570498
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5-oxo-N-[4-(3-phenyl-1,2,4-oxadiazol-5-yl)phenyl]-1-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
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C25H21N5O3
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1
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| 1 |
IC50 = 2120 nM
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CP0579876
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N-[4-[3-(4-bromophenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxo-1-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
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C25H20BrN5O3
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1
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| 1 |
IC50 = 2670 nM
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CP0543227
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N-[4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]phenyl]-1-(furan-2-ylmethyl)-5-oxopyrrolidine-3-carboxamide
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C24H19ClN4O4
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3
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| 1 |
IC50 = 3080 nM
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| 2 |
IC50 = 4520 nM
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| 3 |
IC50 = 13860 nM
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CP0576659
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N-[4-[3-(4-ethylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxo-1-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
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C27H25N5O3
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1
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| 1 |
IC50 = 4040 nM
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CP0570497
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N-[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxo-1-(thiophen-3-ylmethyl)pyrrolidine-3-carboxamide
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C25H22N4O3S
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1
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| 1 |
IC50 = 4340 nM
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CP0579548
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1-(furan-2-ylmethyl)-N-[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxopyrrolidine-3-carboxamide
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C25H22N4O4
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1
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| 1 |
IC50 = 4720 nM
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CP0544864
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1-benzyl-N-[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxopyrrolidine-3-carboxamide
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C27H24N4O3
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2
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| 1 |
IC50 = 4780 nM
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| 2 |
IC50 = 5740 nM
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CP0543239
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1-[(4-fluorophenyl)methyl]-N-[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxopyrrolidine-3-carboxamide
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C27H23FN4O3
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1
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| 1 |
IC50 = 4950 nM
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CP0578525
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N-[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxo-1-(thiophen-2-ylmethyl)pyrrolidine-3-carboxamide
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C25H22N4O3S
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1
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| 1 |
IC50 = 5280 nM
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CP0546656
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N-[4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxo-1-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
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C26H23N5O4
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1
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| 1 |
IC50 = 6130 nM
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CP0576535
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(3S)-1-benzyl-N-[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxopyrrolidine-3-carboxamide
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C27H24N4O3
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1
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| 1 |
IC50 = 6980 nM
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CP0579327
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N-[4-(3-cyclohexyl-1,2,4-oxadiazol-5-yl)phenyl]-5-oxo-1-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
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C25H27N5O3
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1
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| 1 |
IC50 = 7690 nM
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CP0574261
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(3R)-1-benzyl-N-[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxopyrrolidine-3-carboxamide
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C27H24N4O3
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1
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| 1 |
IC50 = 7800 nM
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CP0578086
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1-[(4-methoxyphenyl)methyl]-N-[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxopyrrolidine-3-carboxamide
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C28H26N4O4
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1
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| 1 |
IC50 = 7900 nM
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CP0580130
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1-[(4-methylphenyl)methyl]-N-[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxopyrrolidine-3-carboxamide
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C28H26N4O3
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1
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| 1 |
IC50 = 8510 nM
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CP0543238
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N-[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxo-1-(2-phenylethyl)pyrrolidine-3-carboxamide
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C28H26N4O3
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1
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| 1 |
IC50 > 10000 nM
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CP0546655
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N-[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxo-1-(pyridin-2-ylmethyl)pyrrolidine-3-carboxamide
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C26H23N5O3
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1
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| 1 |
IC50 > 10000 nM
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CP0568889
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5-oxo-N-[4-[3-(4-propan-2-ylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-1-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
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C28H27N5O3
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1
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| 1 |
IC50 > 10000 nM
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CP0570226
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1-[(2-fluorophenyl)methyl]-N-[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxopyrrolidine-3-carboxamide
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C27H23FN4O3
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1
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| 1 |
IC50 > 10000 nM
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CP0576658
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1-[(3-fluorophenyl)methyl]-N-[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-5-oxopyrrolidine-3-carboxamide
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C27H23FN4O3
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1
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| 1 |
IC50 > 10000 nM
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CP0524155
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(4S)-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-5-carbamimidamido-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid
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C138H218N46O34
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1
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| 1 |
Ki = 741.31 nM
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CP0524156
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(4S)-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid
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C140H222N46O35
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1
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| 1 |
Ki = 2089.3 nM
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CP0524157
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(4S)-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid
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C142H225N47O36
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1
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| 1 |
Ki = 2570.4 nM
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CP0550235
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(4S)-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid
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C136H213N43O35
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1
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| 1 |
Ki = 2951.21 nM
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CP0548696
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(4S)-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid
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C139H220N46O34
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1
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| 1 |
Ki = 3388.44 nM
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CP0424400
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(4S)-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-sulfanylpropanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid
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C129H207N43O33S2
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1
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| 1 |
Ki > 10000 nM
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CP0524154
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(4S)-4-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-sulfanylpropanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-[[(2R)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2R)-1-[[2-[[2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
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C128H205N43O33S4
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1
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| 1 |
Ki > 10000 nM
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CP0550236
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(4S)-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoic acid
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C139H220N44O35
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1
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| 1 |
Ki > 10000 nM
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CP0566090
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(4S)-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2R)-1-[[2-[[2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid
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C133H207N43O34S2
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1
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Ki > 10000 nM
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