Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT03048 , C-C chemokine receptor type 1
Gene Name CCR1
Organism Mus musculus, Mouse
Protein Classification Membrane receptor
Uniprot ID P51675
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026  Protein ID: PT03048
 
Compound ID Compound Name Compound Formula
CP0448801
N-[5-chloro-2-[(E)-3-[3-[(4-fluorophenyl)methyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]-3-oxoprop-1-enyl]-4-methoxyphenyl]acetamide
   Show/Hide
C25H27ClFN3O3
 1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
CP0378208
N-[5-chloro-2-[(E)-3-[3-[(4-fluorophenyl)methyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]-3-oxoprop-1-enyl]phenyl]-2-(dimethylamino)acetamide
   Show/Hide
C26H30ClFN4O2
 1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
CP0378011
N-[6-[(E)-3-[3-[(4-fluorophenyl)methyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]-3-oxoprop-1-enyl]quinolin-7-yl]acetamide
   Show/Hide
C27H27FN4O2
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0378207
(R)-N-(2-(3-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-3-oxoprop-1-enyl)-5-chloro-4-methoxyphenyl)acetamide
   Show/Hide
C24H27ClFN3O3
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0378206
(R)-1-(2-(3-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-3-oxoprop-1-enyl)-5-chlorophenyl)urea
   Show/Hide
C22H24ClFN4O2
 1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
CP0445798
N-[5-chloro-2-[(E)-3-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]-3-oxoprop-1-enyl]phenyl]acetamide
   Show/Hide
C22H23ClFN3O2
 1
1
IC50 = 448 nM
   TI
   LI
   LO
   TS
CP0428270
(R)-N-(3-(3-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-3-oxoprop-1-enyl)naphthalen-2-yl)acetamide
   Show/Hide
C27H28FN3O2
 1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
CP0050382
(R)-N-(2-(3-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-3-oxoprop-1-enyl)-5-chlorophenyl)acetamide
   Show/Hide
C23H25ClFN3O2
 1
1
IC50 = 580 nM
   TI
   LI
   LO
   TS
CP0428267
N-[5-chloro-2-[(E)-3-[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazin-1-yl]-3-oxoprop-1-enyl]phenyl]acetamide
   Show/Hide
C24H27ClFN3O2
 1
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
CP0442404
(R)-N-(6-(3-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-3-oxoprop-1-enyl)quinolin-7-yl)acetamide
   Show/Hide
C26H27FN4O2
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0853916
BX 471
   Show/Hide
C21H25Cl2FN4O3
 1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0378007
(R)-N-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethylamino)-5-chlorophenyl)acetamide
   Show/Hide
C22H26ClFN4O2
 1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0378209
(R)-N-(2-(1-(4-fluorobenzyl)-3-methylpiperazine-4-carbonyl)-5-chloro-1H-indol-7-yl)acetamide
   Show/Hide
C23H24ClFN4O2
 1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0428291
(R)-N-(2-(1-(4-fluorobenzyl)-3-methylpiperazine-4-carbonyl)-5-chlorobenzofuran-7-yl)acetamide
   Show/Hide
C23H23ClFN3O3
 1
1
IC50 = 4800 nM
   TI
   LI
   LO
   TS
CP0392271
N-[5-chloro-2-[(E)-3-[(2S,5R)-4-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazin-1-yl]-3-oxoprop-1-enyl]phenyl]acetamide
   Show/Hide
C24H27ClFN3O2
 1
1
IC50 = 23000 nM
   TI
   LI
   LO
   TS