Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT02793 , Free fatty acid receptor 1
Gene Name FFAR1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID O14842
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026  Protein ID: PT02793
 
Compound ID Compound Name Compound Formula
CP0143308
US9688642, 2
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C27H30FN3O4
 2
1
Activity = 1042 nM
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2
EC50 = 894 nM
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CP0459378
(2S,3R)-3-cyclopropyl-3-[3-[[4-(2-fluoro-5-methoxyphenyl)cyclohexyl]methoxy]phenyl]-2-methylpropanoic acid
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C27H33FO4
 1
1
EC50 = 2 nM
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CP0098493
CHEMBL4457303
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C27H32F2O4
 1
1
EC50 = 3.1 nM
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CP0431559
CHEMBL4534836
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C26H30F2O4
 1
1
EC50 = 20 nM
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CP0459377
(2R,3R)-3-cyclopropyl-3-[3-[[4-(2-fluoro-5-methoxyphenyl)cyclohexyl]methoxy]phenyl]-2-methylpropanoic acid
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C27H33FO4
 1
1
EC50 = 22 nM
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CP0384163
(2S,3S)-3-cyclopropyl-2-fluoro-3-[3-[[4-(2-fluoro-5-methoxyphenyl)cyclohexyl]methoxy]phenyl]-2-methylpropanoic acid
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C27H32F2O4
 1
1
EC50 = 89 nM
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CP0384165
(3S)-3-cyclopropyl-3-[3-[[4-(2-fluoro-5-methoxyphenyl)cyclohexyl]methoxy]phenyl]propanoic acid
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C26H31FO4
 1
1
EC50 = 199 nM
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CP0384206
CHEMBL4541658
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C28H35FO4
 1
1
EC50 = 220 nM
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CP0530792
(6E,9E,12E)-octadeca-6,9,12-trienoic acid
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C18H30O2
 1
1
EC50 = 240 nM
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CP0101783
5-[[4-[[3-(2,6-dimethylphenyl)phenyl]methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
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C25H23NO3S
 1
1
EC50 = 1150 nM
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CP0680633
5-(4-((S)-3-(2,4-dichlorophenoxy)-3-phenylpropoxy)benzyl)thiazolidine-2,4-dione
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C25H21Cl2NO4S
 1
1
EC50 = 1660 nM
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CP0680635
5-(4-((1-isobutyl-1H-benzo[d]imidazol-2-yl)methoxy)benzyl)thiazolidine-2,4-dione
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C22H23N3O3S
 1
1
EC50 = 1890 nM
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CP0515601
5-[[4-(2-indol-1-ylethoxy)phenyl]methyl]-1,3-thiazolidine-2,4-dione
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C20H18N2O3S
 1
1
EC50 = 2190 nM
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CP0212793
5-[[4-[(3-bromophenyl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
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C17H14BrNO3S
 1
1
EC50 = 3570 nM
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CP0684617
5-(4-((1-benzyl-1H-benzo[d]imidazol-2-yl)methoxy)benzyl)thiazolidine-2,4-dione
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C25H21N3O3S
 1
1
EC50 = 4110 nM
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CP0409123
5-[[4-[2-(benzimidazol-1-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
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C19H17N3O3S
 1
1
EC50 = 4310 nM
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CP0021358
(6,9,12)-linolenic acid
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C18H30O2
 1
1
EC50 = 4620 nM
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CP0515600
5-[[4-[2-(6-chloroindol-1-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
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C20H17ClN2O3S
 1
1
EC50 = 5060 nM
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CP0158258
5-[[4-[[3-[4-(trifluoromethyl)phenyl]phenyl]methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
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C24H18F3NO3S
 1
1
EC50 = 6110 nM
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CP0680631
5-(4-Benzyloxy-benzyl)-thiazolidine-2,4-dione
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C17H15NO3S
 1
1
EC50 = 6560 nM
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CP0109504
5-[[4-[(3S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
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C26H22F3NO4S
 1
1
EC50 = 7420 nM
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CP0109505
5-[[4-[[3-(2-methylphenyl)phenyl]methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
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C24H21NO3S
 1
1
EC50 = 7730 nM
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CP0680632
5-(4-((S)-3-(4-chlorophenoxy)-3-phenylpropoxy)benzyl)thiazolidine-2,4-dione
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C25H22ClNO4S
 1
1
EC50 = 8510 nM
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CP0101784
5-[[4-[(3-phenylphenyl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
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C23H19NO3S
 1
1
EC50 = 9910 nM
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CP0476307
5-[[4-[2-[phenyl-[4-(trifluoromethyl)phenyl]methoxy]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
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C26H22F3NO4S
 1
1
EC50 = 11330 nM
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CP0684618
5-(4-((1-isopropyl-1H-benzo[d]imidazol-2-yl)methoxy)benzyl)thiazolidine-2,4-dione
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C21H21N3O3S
 1
1
EC50 = 16600 nM
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CP0389900
5-[[4-[2-[(4-methoxyphenyl)-phenylmethoxy]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
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C26H25NO5S
 1
1
EC50 = 17750 nM
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CP0548697
3-[4-[(5-fluoro-2-methylphenoxy)methyl]phenyl]propanoic acid
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C17H17FO3
 1
1
EC50 = 19054.61 nM
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CP0074754
5-[[4-[(3S)-3-(3-methoxyphenoxy)-3-phenylpropoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
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C26H25NO5S
 1
1
EC50 = 19580 nM
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CP0555347
3-[4-[(2-cyano-5-fluorophenoxy)methyl]phenyl]propanoic acid
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C17H14FNO3
 1
1
EC50 = 20417.38 nM
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CP0680636
5-(4-((1-allyl-1H-benzo[d]imidazol-2-yl)methoxy)benzyl)thiazolidine-2,4-dione
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C21H19N3O3S
 1
1
EC50 = 21010 nM
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CP0515602
5-[[4-(2-benzhydryloxyethoxy)phenyl]methyl]-1,3-thiazolidine-2,4-dione
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C25H23NO4S
 1
1
EC50 = 21340 nM
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CP0232299
5-[[4-[(4-bromophenyl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
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C17H14BrNO3S
 1
1
EC50 = 23120 nM
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CP0421627
N-[4-amino-3-(trifluoromethyl)phenyl]-4-bromobenzenesulfonamide
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C13H10BrF3N2O2S
 1
1
EC50 = 28840.32 nM
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CP0555346
3-[4-[(2-bromo-5-fluorophenoxy)methyl]phenyl]propanoic acid
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C16H14BrFO3
 1
1
EC50 = 30199.52 nM
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CP0421631
3-[4-[(5-fluoro-2-methoxyphenoxy)methyl]phenyl]propanoic acid
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C17H17FO4
 1
1
EC50 = 30902.95 nM
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CP0145583
3-[4-[[5-fluoro-2-(4-methylphenyl)phenyl]methoxy]phenyl]propanoic acid
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C23H21FO3
 1
1
EC50 = 33884.42 nM
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CP0018150
4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfonamide
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C14H12F3NO2S
 1
1
EC50 = 48977.88 nM
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CP0444003
N-[4-amino-3-(trifluoromethyl)phenyl]-4-chlorobenzenesulfonamide
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C13H10ClF3N2O2S
 1
1
EC50 = 56234.13 nM
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CP0516865
N-[4-amino-3-(trifluoromethyl)phenyl]-4-tert-butylbenzenesulfonamide
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C17H19F3N2O2S
 1
1
EC50 = 67608.3 nM
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CP0176090
3-[4-[[5-fluoro-2-(4-methylphenyl)phenoxy]methyl]phenyl]propanoic acid
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C23H21FO3
 1
1
EC50 < 100000 nM
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CP0271129
N-(4-aminophenyl)benzenesulfonamide
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C12H12N2O2S
 1
1
EC50 < 100000 nM
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CP0421624
N-[4-amino-3-(trifluoromethyl)phenyl]-4-nitrobenzenesulfonamide
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C13H10F3N3O4S
 1
1
EC50 < 100000 nM
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CP0421625
3-[4-[(5-fluoro-2-methoxycarbonylphenoxy)methyl]phenyl]propanoic acid
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C18H17FO5
 1
1
EC50 < 100000 nM
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CP0421626
2-[[4-(2-carboxyethyl)phenyl]methoxy]-4-fluorobenzoic acid
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C17H15FO5
 1
1
EC50 < 100000 nM
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CP0421629
N-[4-amino-3-(trifluoromethyl)phenyl]-4-methoxybenzenesulfonamide
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C14H13F3N2O3S
 1
1
EC50 < 100000 nM
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CP0444000
N-[4-amino-3-(trifluoromethyl)phenyl]-4-ethylbenzenesulfonamide
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C15H15F3N2O2S
 1
1
EC50 < 100000 nM
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CP0444001
N-[4-amino-3-(trifluoromethyl)phenyl]-4-methylbenzenesulfonamide
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C14H13F3N2O2S
 1
1
EC50 < 100000 nM
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CP0450881
N-(4-amino-3-methylphenyl)benzenesulfonamide
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C13H14N2O2S
 1
1
EC50 < 100000 nM
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CP0516866
N-[4-amino-3-(trifluoromethyl)phenyl]-4-(trifluoromethoxy)benzenesulfonamide
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C14H10F6N2O3S
 1
1
EC50 < 100000 nM
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CP0516867
N-[4-amino-3-(trifluoromethyl)phenyl]-4-phenylbenzenesulfonamide
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C19H15F3N2O2S
 1
1
EC50 < 100000 nM
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CP0528378
N-[4-amino-3-(trifluoromethyl)phenyl]benzenesulfonamide
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C13H11F3N2O2S
 1
1
EC50 < 100000 nM
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CP0546071
N-(4-amino-3-nitrophenyl)benzenesulfonamide
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C12H11N3O4S
 1
1
EC50 < 100000 nM
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CP0560519
N-[4-amino-3-(trifluoromethyl)phenyl]-4-hydroxybenzenesulfonamide
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C13H11F3N2O3S
 1
1
EC50 < 100000 nM
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CP0560520
N-[4-amino-3-(trifluoromethyl)phenyl]-4-fluorobenzenesulfonamide
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C13H10F4N2O2S
 1
1
EC50 < 100000 nM
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CP0562782
N-(4-amino-3-fluorophenyl)benzenesulfonamide
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C12H11FN2O2S
 1
1
EC50 < 100000 nM
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