Compound ID |
Compound Name |
Compound Formula |
CP0422892
|
4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)-amino]pyridin-2-yl}piperazine-1-carboxylic Acid Ethyl Ester
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|
C23H22F3N5O4
|
1
|
1 |
EC50 = 93 nM
|
|
|
CP0372079
|
2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid[6-(4-Cyclopropanecarbonylpiperazin-1-yl)pyridin-3-yl]-amide
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|
C24H22F3N5O3
|
1
|
1 |
EC50 = 138 nM
|
|
|
CP0372080
|
2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid[4-(4-Cyclopropanecarbonylpiperazin-1-yl)phenyl]amide
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|
C25H23F3N4O3
|
1
|
1 |
EC50 = 165 nM
|
|
|
CP0494540
|
4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)-amino]phenyl}piperazine-1-carboxylic Acid Methyl Ester
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|
C23H21F3N4O4
|
1
|
1 |
EC50 = 190 nM
|
|
|
CP0494541
|
4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)-amino]pyridin-2-yl}piperazine-1-carboxylic Acid Methyl Ester
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|
C22H20F3N5O4
|
1
|
1 |
EC50 = 216 nM
|
|
|
CP0478472
|
5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)amino]-3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-carboxylic AcidMethyl Ester
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|
C23H21F3N4O4
|
1
|
1 |
EC50 = 219 nM
|
|
|
CP0498653
|
4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)-amino]phenyl}piperidine-1-carbonyl)-cis-cyclohexanecarboxylic Acid
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|
C30H30F3N3O5
|
1
|
1 |
EC50 = 220 nM
|
|
|
CP0489764
|
2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid[6-(3-Ethoxyazetidin-1-yl)pyridin-3-yl]amide
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|
C21H19F3N4O3
|
1
|
1 |
EC50 = 228 nM
|
|
|
CP0372083
|
N-[4-[1-(cyclopropanecarbonyl)piperidin-4-yl]phenyl]-2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide
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|
C26H24F3N3O3
|
1
|
1 |
EC50 = 362 nM
|
|
|
CP0372077
|
4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)-amino]phenyl}piperazine-1-carbonyl)-cis-cyclohexanecarboxylic Acid
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|
C29H29F3N4O5
|
1
|
1 |
EC50 = 365 nM
|
|
|
CP0273348
|
4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)-amino]phenyl}piperidine-1-carboxylic Acid Methyl Ester
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|
C24H22F3N3O4
|
2
|
1 |
EC50 = 371 nM
|
|
|
2 |
EC50 < 1000 nM
|
|
|
CP0498948
|
2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid(1'-Cyclopropanecarbonyl-1',2',3',4',5',6'-hexahydro[2,4']bipyridinyl-5-yl)amide
Show/Hide
|
C25H23F3N4O3
|
1
|
1 |
EC50 = 378 nM
|
|
|
CP0498947
|
4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)amino]-pyrimidin-2-yl}piperazine-1-carboxylic Acid Methyl Ester
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|
C21H19F3N6O4
|
1
|
1 |
EC50 = 410 nM
|
|
|
CP0275315
|
N-(6-morpholin-4-ylpyridin-3-yl)-5-phenyl-2-(trifluoromethyl)furan-3-carboxamide
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|
C21H18F3N3O3
|
1
|
1 |
EC50 = 490 nM
|
|
|
CP0050575
|
4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)-amino]phenyl}piperidine-1-carbonyl)-trans-cyclohexanecarboxylic Acid
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|
C30H30F3N3O5
|
1
|
1 |
EC50 = 493 nM
|
|
|
CP0498434
|
2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid{2-[(2-Methoxyethyl)methylamino]pyrimidin-5-yl}amide
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|
C19H18F3N5O3
|
1
|
1 |
EC50 = 534 nM
|
|
|
CP0137702
|
2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid{6-[(2-Methoxyethyl)methylamino]pyridin-3-yl}amide
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|
C20H19F3N4O3
|
2
|
1 |
EC50 = 660 nM
|
|
|
2 |
EC50 = 661 nM
|
|
|
CP0291275
|
N-(6-morpholin-4-ylpyridin-3-yl)-2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide
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|
C20H17F3N4O3
|
1
|
1 |
EC50 = 840 nM
|
|
|
CP0205880
|
N-[6-(diethylamino)pyridin-3-yl]-2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide
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|
C20H19F3N4O2
|
1
|
1 |
EC50 = 910 nM
|
|
|
CP0422894
|
4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)-amino]phenyl}piperazine-1-carbonyl)-trans-cyclohexanecarboxylic Acid
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|
C29H29F3N4O5
|
1
|
1 |
EC50 = 1070 nM
|
|
|
CP0037325
|
2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl}phenyl)cyclohexyl]acetic acid
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|
C22H26N4O3
|
1
|
1 |
EC50 = 1436 nM
|
|
|
CP0260178
|
N-(2-morpholin-4-ylpyrimidin-5-yl)-2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide
Show/Hide
|
C19H16F3N5O3
|
1
|
1 |
EC50 = 1500 nM
|
|
|
CP0372082
|
4-(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)-amino]pyridin-2-yl}piperazine-1-carbonyl)-trans-cyclohexanecarboxylic Acid
Show/Hide
|
C28H28F3N5O5
|
1
|
1 |
EC50 = 1764 nM
|
|
|
CP0422891
|
2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid{4-[(2-Methoxyethyl)methylamino]phenyl}amide
Show/Hide
|
C21H20F3N3O3
|
1
|
1 |
EC50 = 1803 nM
|
|
|
CP0422893
|
4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)amino]-3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-carbonyl}-transcyclohexanecarboxylic Acid
Show/Hide
|
C29H29F3N4O5
|
1
|
1 |
EC50 = 2363 nM
|
|
|
CP0191591
|
N-(3-oxo-1-propyl-2H-indazol-5-yl)-2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide
Show/Hide
|
C21H17F3N4O3
|
1
|
1 |
EC50 = 2500 nM
|
|
|
CP0151924
|
N-(4-morpholin-4-ylphenyl)-2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide
Show/Hide
|
C21H18F3N3O3
|
1
|
1 |
EC50 = 2700 nM
|
|
|
CP0260179
|
5-chloro-N-(6-morpholin-4-ylpyridin-3-yl)-2-phenyl-1,3-oxazole-4-carboxamide
Show/Hide
|
C19H17ClN4O3
|
1
|
1 |
EC50 = 2990 nM
|
|
|
CP0275314
|
5-ethyl-N-(6-morpholin-4-ylpyridin-3-yl)-2-phenyl-1,3-oxazole-4-carboxamide
Show/Hide
|
C21H22N4O3
|
1
|
1 |
EC50 = 3420 nM
|
|
|
CP0291276
|
N-(2-morpholin-4-yl-1,3-thiazol-5-yl)-2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide
Show/Hide
|
C18H15F3N4O3S
|
1
|
1 |
EC50 = 3700 nM
|
|
|
CP0372078
|
(S)-2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid-[2-(3-Hydroxypyrrolidin-1-yl)pyrimidin-5-yl]amide
Show/Hide
|
C19H16F3N5O3
|
1
|
1 |
EC50 = 5660 nM
|
|
|
CP0291277
|
4-methyl-N-(6-morpholin-4-ylpyridin-3-yl)-2-phenyl-1,3-oxazole-5-carboxamide
Show/Hide
|
C20H20N4O3
|
1
|
1 |
EC50 = 7460 nM
|
|
|
CP0260180
|
N-[6-[2-hydroxyethyl(methyl)amino]pyridin-3-yl]-2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide
Show/Hide
|
C19H17F3N4O3
|
1
|
1 |
EC50 = 8090 nM
|
|
|
CP0077134
|
N-[6-[ethyl(2-methoxyethyl)amino]pyridin-3-yl]-2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide
Show/Hide
|
C21H21F3N4O3
|
1
|
1 |
EC50 = 8900 nM
|
|
|
CP0339410
|
N-[6-(2-methoxyethylamino)pyridin-3-yl]-2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide
Show/Hide
|
C19H17F3N4O3
|
1
|
1 |
EC50 = 11060 nM
|
|
|
CP0275237
|
4-methyl-N-(6-morpholin-4-ylpyridin-3-yl)-2-phenyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C20H20N4O2S
|
1
|
1 |
EC50 = 11800 nM
|
|
|
CP0425840
|
(1-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)-amino]pyridin-2-yl}azetidin-3-yloxy)acetic Acid
Show/Hide
|
C21H17F3N4O5
|
1
|
1 |
EC50 > 25000 nM
|
|
|
CP0460210
|
2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid{6-[(2-Methoxyethyl)methylamino]pyridin-3-yl}methylamide
Show/Hide
|
C21H21F3N4O3
|
1
|
1 |
EC50 > 25000 nM
|
|
|
CP0494378
|
2-Methyl-5-trifluoromethyloxazole-4-carboxylic Acid{6-[(2-Methoxyethyl)methylamino]pyridin-3-yl}amide
Show/Hide
|
C15H17F3N4O3
|
1
|
1 |
EC50 > 25000 nM
|
|
|
CP0498945
|
2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid[6-(3,3-Difluoroazetidin-1-yl)pyridin-3-yl]amide
Show/Hide
|
C19H13F5N4O2
|
1
|
1 |
EC50 = 25000 nM
|
|
|
CP0260181
|
N-[6-[(2-methoxyacetyl)-methylamino]pyridin-3-yl]-2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide
Show/Hide
|
C20H17F3N4O4
|
1
|
1 |
EC50 > 25000 nM
|
|
|