| Compound ID |
Compound Name |
Compound Formula |
|
CP0127467
|
2-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-4-pyridinecarbonitrile
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|
C21H15F2N5
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0384295
|
3-[4-(3,5-difluorophenyl)phenyl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
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|
C20H23F2N3O3S
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0546237
|
3-[4-(3,5-difluorophenyl)cyclohexyl]-1-(1-ethylsulfonylpiperidin-4-yl)-1-methylurea
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|
C21H31F2N3O3S
|
1
|
| 1 |
Ki = 0.75 nM
|
|
|
|
CP0384297
|
3-[1-(3,5-dichlorophenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
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|
C19H28Cl2N4O3S
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0496923
|
3-[4-(3,5-difluorophenyl)cyclohexyl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
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|
C20H29F2N3O3S
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0536170
|
CHEMBL403918
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|
C22H31F2N3O2
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0036766
|
1-(1-acetylpiperidin-4-yl)-3-[4-(3,5-difluorophenyl)cyclohexyl]-1-methylurea
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|
C21H29F2N3O2
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0422335
|
3-[1-(3,5-difluorophenyl)piperidin-4-yl]-1-methyl-1-[1-(2-methylpropanoyl)piperidin-4-yl]urea
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|
C22H32F2N4O2
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0404870
|
3-[1-(3,5-difluorophenyl)piperidin-4-yl]-1-(1-ethylsulfonylpiperidin-4-yl)-1-methylurea
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|
C20H30F2N4O3S
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0431805
|
3-[1-(3,5-difluorophenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
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|
C19H28F2N4O3S
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0440927
|
3-[1-(3,5-difluorophenyl)piperidin-4-yl]-1-methyl-1-(1-propan-2-ylsulfonylpiperidin-4-yl)urea
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|
C21H32F2N4O3S
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0525736
|
3-[1-(3,5-difluorophenyl)piperidin-4-yl]-1-methyl-1-(1-propylsulfonylpiperidin-4-yl)urea
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|
C21H32F2N4O3S
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0464113
|
1-(1-butanoylpiperidin-4-yl)-3-[1-(3,5-difluorophenyl)piperidin-4-yl]-1-methylurea
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|
C22H32F2N4O2
|
1
|
| 1 |
Ki = 5.9 nM
|
|
|
|
CP0372733
|
3-[1-(3,5-difluorophenyl)piperidin-4-yl]-1-methyl-1-(1-propanoylpiperidin-4-yl)urea
Show/Hide
|
C21H30F2N4O2
|
1
|
| 1 |
Ki = 6.3 nM
|
|
|
|
CP0372734
|
1-(1-acetylpiperidin-4-yl)-3-[1-(3,5-difluorophenyl)piperidin-4-yl]-1-methylurea
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|
C20H28F2N4O2
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0525734
|
3-[1-(3-bromophenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
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|
C19H29BrN4O3S
|
1
|
| 1 |
Ki = 8.8 nM
|
|
|
|
CP0440930
|
3-[1-(3-chlorophenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
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|
C19H29ClN4O3S
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0431804
|
1-methyl-3-[1-(3-methylphenyl)piperidin-4-yl]-1-(1-methylsulfonylpiperidin-4-yl)urea
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|
C20H32N4O3S
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0457164
|
3-[1-(3-cyanophenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
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|
C20H29N5O3S
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0530778
|
3-[1-(3-fluorophenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
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|
C19H29FN4O3S
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0501247
|
3-[1-(3,4-dichlorophenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
Show/Hide
|
C19H28Cl2N4O3S
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0440928
|
1-methyl-1-(1-methylsulfonylpiperidin-4-yl)-3-(4-phenylcyclohexyl)urea
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|
C20H31N3O3S
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0457165
|
1-methyl-3-[1-(2-methylphenyl)piperidin-4-yl]-1-(1-methylsulfonylpiperidin-4-yl)urea
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|
C20H32N4O3S
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0373041
|
1-(1-acetylpiperidin-4-yl)-1-methyl-3-(4-phenylcyclohexyl)urea
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|
C21H31N3O2
|
1
|
| 1 |
Ki = 59 nM
|
|
|
|
CP0525735
|
3-[1-(2-fluorophenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
Show/Hide
|
C19H29FN4O3S
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0501249
|
3-[1-(4-chlorophenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
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|
C19H29ClN4O3S
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0536171
|
3-[1-(3-chloro-4-fluorophenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
Show/Hide
|
C19H28ClFN4O3S
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0457163
|
3-[1-(3-acetylphenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
Show/Hide
|
C21H32N4O4S
|
1
|
| 1 |
Ki = 164 nM
|
|
|
|
CP0440931
|
1-methyl-1-(1-methylsulfonylpiperidin-4-yl)-3-(1-phenylpiperidin-4-yl)urea
Show/Hide
|
C19H30N4O3S
|
1
|
| 1 |
Ki = 303 nM
|
|
|
|
CP0440929
|
3-[1-(3-methoxyphenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
Show/Hide
|
C20H32N4O4S
|
1
|
| 1 |
Ki = 311 nM
|
|
|
|
CP0372732
|
3-[1-(3,4-difluorophenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
Show/Hide
|
C19H28F2N4O3S
|
1
|
| 1 |
Ki = 312 nM
|
|
|
|
CP0457166
|
1-methyl-1-(1-methylsulfonylpiperidin-4-yl)-3-(1-pyridin-3-ylpiperidin-4-yl)urea
Show/Hide
|
C18H29N5O3S
|
1
|
| 1 |
Ki = 405 nM
|
|
|
|
CP0457161
|
1-methyl-1-(1-methylsulfonylpiperidin-4-yl)-3-(4-phenylcyclohexyl)urea
Show/Hide
|
C20H31N3O3S
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0457162
|
3-[1-(4-fluorophenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
Show/Hide
|
C19H29FN4O3S
|
1
|
| 1 |
Ki = 799 nM
|
|
|
|
CP0431803
|
3-[1-(4-bromophenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
Show/Hide
|
C19H29BrN4O3S
|
1
|
| 1 |
Ki = 819 nM
|
|
|
|
CP0504615
|
(S)-N-(4-(4-phenyl-5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
Show/Hide
|
C25H24N4S2
|
1
|
| 1 |
Ki = 5978 nM
|
|
|
|
CP0411181
|
N-[2-[4-(4,5-dihydro-1,3-thiazol-2-ylamino)phenyl]ethyl]-1,3-benzothiazol-2-amine
Show/Hide
|
C18H18N4S2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0382078
|
1-(1-acetylpiperidin-4-yl)-1-methyl-3-(4-phenylcyclohexyl)urea
Show/Hide
|
C21H31N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
