Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridyl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-4-pyridinecarbonitrile
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 PubChem ID
CID: 42630820
SID: 81069780
Canonical SMILES
C[C@@H]1NC(=N[C@@]1(c1ccc(F)cc1)c1ccc(F)nc1)c1cc(ccn1)C#N
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Compound Formula C21H15F2N5
Compound Structure
Protein Name
 Protein Info 
Neuropeptide Y receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neuropeptide Y receptor
Uniprot ID
Q15761
Gene Name
NPY5R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CL000101 L-M(TK-)
 Cell Line Info 
Mus musculus (Mouse)  1
1
Ki = 1.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.3 nM