Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
 Cell Line Info 
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT05025 , Adenosine receptor A3
 Protein Info 
Gene Name ADORA3
Organism Mus musculus, Mouse
Protein Classification Membrane receptor
Uniprot ID Q61618
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025
 Cell Line Info 
 Protein ID: PT05025
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0076893
 Compound Info 
methyl (2S,3S,4R,5R)-5-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-3,4-dihydroxyoxolane-2-carboxylate
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C18H16ClN5O5S
  1
1
Ki = 34 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0076892
 Compound Info 
(2S,3S,4R,5R)-5-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(propylamino)purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide
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C20H21ClN6O4S
  1
1
Ki = 597 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0076890
 Compound Info 
(2S,3S,4R,5R)-5-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide
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C18H17ClN6O4S
  1
1
Ki = 1170 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393809
 Compound Info 
ethyl (1S,2R,3S,4R,5S)-4-[2-[2-(5-bromothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylate
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C21H20BrN5O4S
  1
1
Ki = 1800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393511
 Compound Info 
propyl (1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylate
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C22H22ClN5O4S
  1
1
Ki = 2810 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS