Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
 Cell Line Info 
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT05005 , Interleukin-1 receptor antagonist protein
 Protein Info 
Gene Name IL1RN
Organism Homo sapiens, Human
Protein Classification Unclassified protein
Uniprot ID P18510
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025
 Cell Line Info 
 Protein ID: PT05005
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0139134
 Compound Info 
2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,10-dioxo-1,2-dithia-5,9-diazacyclotridecane-4-carboxamido)methyl)phenyl)acetic acid
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C26H32N4O6S2
  2
1
IC50 = 18 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 10.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0537156
 Compound Info 
(4R,8S,11S)-11-amino-N-[[2-(2-amino-2-oxoethyl)phenyl]methyl]-8-[(4-hydroxyphenyl)methyl]-6,10-dioxo-1,2-dithia-5,9-diazacyclotridecane-4-carboxamide
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C26H33N5O5S2
  2
1
IC50 = 39 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 23.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0553595
 Compound Info 
(4R,8S,11S)-11-amino-N-[[2-(2-amino-2-oxoethyl)phenyl]methyl]-8-[(4-fluorophenyl)methyl]-6,10-dioxo-1,2-dithia-5,9-diazacyclotridecane-4-carboxamide
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C26H32FN5O4S2
  2
1
IC50 = 330 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 200.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0551781
 Compound Info 
2-[2-[[[(4S,8S,11S)-11-amino-8-[(4-hydroxyphenyl)methyl]-6,10,14-trioxo-1,5,9-triazacyclotetradecane-4-carbonyl]amino]methyl]phenyl]acetic acid
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C28H35N5O7
  2
1
IC50 = 1110 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 674.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0553596
 Compound Info 
2-[2-[[[(2S,6S,13S)-13-amino-2-[(4-hydroxyphenyl)methyl]-4,9,14-trioxo-1,5,10-triazacyclotetradecane-6-carbonyl]amino]methyl]phenyl]acetic acid
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C28H35N5O7
  2
1
IC50 = 1460 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 887 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0560323
 Compound Info 
(4R,8S,11S)-11-amino-N-[[2-(2-amino-2-oxoethyl)phenyl]methyl]-8-[(4-hydroxyphenyl)methyl]-6-oxo-1,2-dithia-5,9-diazacyclotridecane-4-carboxamide
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C26H35N5O4S2
  2
1
IC50 = 2060 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 1251.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0511971
 Compound Info 
2-[2-[[[(3S,6S,10S)-3-amino-6-[(4-hydroxyphenyl)methyl]-4,8,13-trioxo-1,5,9-triazacyclotridecane-10-carbonyl]amino]methyl]phenyl]acetic acid
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C27H33N5O7
  2
1
IC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki > 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0553907
 Compound Info 
2-[2-[[[(4R,8S)-8-[(4-hydroxyphenyl)methyl]-6-oxo-1,2-dithia-5,9-diazacyclotridecane-4-carbonyl]amino]methyl]phenyl]acetic acid
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C26H33N3O5S2
  2
1
IC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki > 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS