Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
 Cell Line Info 
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT04975 , G-protein coupled bile acid receptor 1
 Protein Info 
Gene Name GPBAR1
Organism Mus musculus, Mouse
Protein Classification Membrane receptor
Uniprot ID Q80SS6
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025
 Cell Line Info 
 Protein ID: PT04975
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0441788
 Compound Info 
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dichlorophenoxy)pyridin-3-yl]methanone
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C23H19Cl2N3O2
  1
1
EC50 = 3.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0191847
 Compound Info 
6alpha-ethyl-23(S)-methyl-cholic acid
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C27H46O5
  1
1
EC50 = 132 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0311846
 Compound Info 
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[3-[(2,4-dichlorophenyl)methyl]imidazol-4-yl]methanone
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C22H20Cl2N4O
  1
1
EC50 = 611 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0557132
 Compound Info 
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[3-[(2,5-dichlorophenyl)methyl]imidazol-4-yl]methanone
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C22H20Cl2N4O
  1
1
EC50 = 832 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552775
 Compound Info 
(3-benzylimidazol-4-yl)-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
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C22H22N4O
  1
1
EC50 = 3500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0511967
 Compound Info 
[3-[(2-chlorophenyl)methyl]imidazol-4-yl]-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
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C22H21ClN4O
  1
1
EC50 = 3690 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0514895
 Compound Info 
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[3-[(2,4-difluorophenyl)methyl]imidazol-4-yl]methanone
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C22H20F2N4O
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552776
 Compound Info 
(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[3-[(4-fluorophenyl)methyl]imidazol-4-yl]methanone
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C22H21FN4O
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS