Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
 Cell Line Info 
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT04390 , Lysine-specific demethylase 4B
 Protein Info 
Gene Name KDM4B
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID O94953
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025
 Cell Line Info 
 Protein ID: PT04390
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0061173
 Compound Info 
8-[4-[2-[4-(3-chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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C23H23ClN6O
  1
1
EC50 = 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0138240
 Compound Info 
8-[4-(2-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylethyl)pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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C25H26N6O
  1
1
EC50 = 1300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0236796
 Compound Info 
8-[4-[2-[4-(3-pyridin-3-ylphenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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C28H27N7O
  1
1
EC50 = 1400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0236794
 Compound Info 
8-[4-[2-[4-(3-chlorophenyl)-4-methylpiperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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C24H25ClN6O
  1
1
EC50 = 1700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0138235
 Compound Info 
8-[4-[2-[4-(3-fluorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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C23H23FN6O
  1
1
EC50 = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0138214
 Compound Info 
8-[4-[2-[4-[3-[2-(dimethylamino)ethyl]phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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C27H33N7O
  1
1
EC50 = 3000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0234557
 Compound Info 
8-[4-[2-[4-[4-[2-(dimethylamino)ethyl]phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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C27H33N7O
  1
1
EC50 = 3500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0138238
 Compound Info 
8-[4-[1-(cyclobutylmethyl)piperidin-4-yl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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C20H24N6O
  1
1
EC50 = 9100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS