Brief Information of the Compound and Protein
Compound Name
8-[4-[2-[4-(3-pyridin-3-ylphenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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PubChem ID
CID: 155560356
Canonical SMILES
O=c1[nH]cnc2c(nccc12)-n1cc(CCN2CCC(CC2)c2cccc(c2)-c2cccnc2)cn1
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Compound Formula C28H27N7O
Compound Structure
Protein Name
Lysine-specific demethylase 4B
Protein Classification
Epigenetic regulator
>
Eraser
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Lysine demethylase
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Lysine-specific demethylase
Uniprot ID
O94953
Gene Name
KDM4B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
EC50 = 1400 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 27 nM
   TI
   LI
   LO
   TS