| Compound ID |
Compound Name |
Compound Formula |
|
CP0357027
|
3-[3-[4-[(oxan-4-ylamino)methyl]phenyl]-1,2-oxazol-5-yl]-5-(4-propan-2-ylsulfonylphenyl)pyrazin-2-amine
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|
C28H31N5O4S
|
1
|
| 1 |
Ki = 0.14 nM
|
|
|
|
CP0021486
|
3-[3-[4-[dideuterio(methylamino)methyl]phenyl]isoxazol-5-yl]-5-(4-isopropylsulfonylphenyl)pyrazin-2-amine
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|
C24H25N5O3S
|
1
|
| 1 |
Ki = 0.165 nM
|
|
|
|
CP0189607
|
US10479784, Compound IIA-10
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|
C25H27N5O3S
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
|
CP0353137
|
US10479784, Compound IIA-5
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|
C23H23N5O3S
|
1
|
| 1 |
Ki = 0.27 nM
|
|
|
|
CP0262576
|
3-[3-[4-[(1R)-1-aminoethyl]phenyl]-1,2-oxazol-5-yl]-5-(4-propan-2-ylsulfonylphenyl)pyrazin-2-amine
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|
C24H25N5O3S
|
1
|
| 1 |
Ki = 0.53 nM
|
|
|
|
CP0180330
|
3-[3-[2-chloro-4-(methylaminomethyl)phenyl]-1,2-oxazol-5-yl]-5-(4-propan-2-ylsulfonylphenyl)pyrazin-2-amine
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|
C24H24ClN5O3S
|
1
|
| 1 |
Ki = 0.75 nM
|
|
|
|
CP0238624
|
3-(3-phenyl-1,2-oxazol-5-yl)-5-(4-propan-2-ylsulfonylphenyl)pyrazin-2-amine
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|
C22H20N4O3S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0353138
|
3-(5-phenyl-1,3,4-thiadiazol-2-yl)-5-(4-propan-2-ylsulfonylphenyl)pyrazin-2-amine
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|
C21H19N5O2S2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0532519
|
US10479784, Compound IA-116
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|
C21H19N5O3S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0353108
|
3-[3-[4-[(1S)-1-aminoethyl]phenyl]-1,2-oxazol-5-yl]-5-(4-propan-2-ylsulfonylphenyl)pyrazin-2-amine
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|
C24H25N5O3S
|
1
|
| 1 |
Ki = 1.24 nM
|
|
|
|
CP0180329
|
3-(5-phenyl-1,2-oxazol-3-yl)-5-(4-propan-2-ylsulfonylphenyl)pyrazin-2-amine
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|
C22H20N4O3S
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0451189
|
US10479784, Compound IIA-13
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|
C24H24ClN5O3S
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0180289
|
3-amino-6-(4-(isopropylsulfonyl)phenyl)-N-phenylpyrazine-2-carboxamide
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|
C20H20N4O3S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0446600
|
3-(5-phenyl-1,3-oxazol-2-yl)-5-(4-propan-2-ylsulfonylphenyl)pyrazin-2-amine
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|
C22H20N4O3S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0249176
|
3-(5-phenyl-1,2,4-oxadiazol-3-yl)-5-(4-propan-2-ylsulfonylphenyl)pyrazin-2-amine
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|
C21H19N5O3S
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0238623
|
US8846917, I-1
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|
C21H20N6O2S
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0141513
|
3-(2-phenyl-1,3-oxazol-5-yl)-5-(4-propan-2-ylsulfonylphenyl)pyrazin-2-amine
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|
C22H20N4O3S
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0571497
|
3-(3-phenyl-1,2,4-oxadiazol-5-yl)-5-(4-propan-2-ylsulfonylphenyl)pyrazin-2-amine
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|
C21H19N5O3S
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0141550
|
3-(3-phenyl-4,5-dihydro-1,2-oxazol-5-yl)-5-(4-propan-2-ylsulfonylphenyl)pyrazin-2-amine
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|
C22H22N4O3S
|
1
|
| 1 |
Ki = 90 nM
|
|
|
