| Compound ID |
Compound Name |
Compound Formula |
|
CP0003740
|
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide
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|
C17H12F9NO3S
|
1
|
| 1 |
EC50 = 260 nM
|
|
|
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CP0550100
|
2-[4-[dimethyl(prop-2-enyl)silyl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
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|
C14H16F6OSi
|
1
|
| 1 |
EC50 = 450 nM
|
|
|
|
CP0567786
|
2-[4-[dimethyl(trimethylsilyl)silyl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
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|
C14H20F6OSi2
|
1
|
| 1 |
EC50 = 510 nM
|
|
|
|
CP0569310
|
1,1,1,3,3,3-hexafluoro-2-(4-triethylsilylphenyl)propan-2-ol
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|
C15H20F6OSi
|
1
|
| 1 |
EC50 = 530 nM
|
|
|
|
CP0543301
|
1,1,1,3,3,3-hexafluoro-2-(4-tripropylsilylphenyl)propan-2-ol
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|
C18H26F6OSi
|
1
|
| 1 |
EC50 = 590 nM
|
|
|
|
CP0543302
|
2-[4-[tert-butyl(dimethyl)silyl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
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|
C15H20F6OSi
|
1
|
| 1 |
EC50 = 650 nM
|
|
|
|
CP0568748
|
2-[4-[diethyl(methyl)silyl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
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|
C14H18F6OSi
|
1
|
| 1 |
EC50 = 690 nM
|
|
|
|
CP0564479
|
2-[4-[benzyl(dimethyl)silyl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
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|
C18H18F6OSi
|
1
|
| 1 |
EC50 = 720 nM
|
|
|
|
CP0569311
|
2-[4-[dimethyl(phenyl)silyl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
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|
C17H16F6OSi
|
1
|
| 1 |
EC50 = 740 nM
|
|
|
|
CP0579889
|
2-[4-[cyclohexyl(dimethyl)silyl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
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|
C17H22F6OSi
|
1
|
| 1 |
EC50 = 740 nM
|
|
|
|
CP0570104
|
1,1,1,3,3,3-hexafluoro-2-(4-trimethylsilylphenyl)propan-2-ol
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|
C12H14F6OSi
|
1
|
| 1 |
EC50 = 1410 nM
|
|
|
|
CP0550102
|
2-[4-[butyl(dimethyl)silyl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
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|
C15H20F6OSi
|
1
|
| 1 |
EC50 = 1700 nM
|
|
|
|
CP0567788
|
1,1,1,3,3,3-hexafluoro-2-[4-[2-hydroxyethyl(dimethyl)silyl]phenyl]propan-2-ol
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|
C13H16F6O2Si
|
1
|
| 1 |
EC50 = 1730 nM
|
|
|
|
CP0567787
|
2-[4-[ethenyl(dimethyl)silyl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
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|
C13H14F6OSi
|
1
|
| 1 |
EC50 = 1800 nM
|
|
|
|
CP0567785
|
1,1,1,3,3,3-hexafluoro-2-(4-tribenzylsilylphenyl)propan-2-ol
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|
C30H26F6OSi
|
1
|
| 1 |
EC50 = 1980 nM
|
|
|
|
CP0257822
|
N-(2-methylpropyl)-N-[[4-(4-methylsulfonylphenyl)phenyl]methyl]-1-phenylmethanesulfonamide
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|
C25H29NO4S2
|
2
|
| 1 |
EC50 = 2500 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0110590
|
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-methylbenzenesulfonamide
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|
C16H13F6NO3S
|
1
|
| 1 |
EC50 = 2930 nM
|
|
|
|
CP0551761
|
1,1,1,3,3,3-hexafluoro-2-[4-[1-hydroxyethyl(dimethyl)silyl]phenyl]propan-2-ol
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|
C13H16F6O2Si
|
1
|
| 1 |
EC50 = 3340 nM
|
|
|
|
CP0544945
|
1,1,1,3,3,3-hexafluoro-2-[4-[3-hydroxypropyl(dimethyl)silyl]phenyl]propan-2-ol
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|
C14H18F6O2Si
|
1
|
| 1 |
EC50 = 4030 nM
|
|
|
|
CP0576345
|
1,1,1,3,3,3-hexafluoro-2-[4-(hydroxy-methyl-phenylsilyl)phenyl]propan-2-ol
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|
C16H14F6O2Si
|
1
|
| 1 |
EC50 = 5030 nM
|
|
|
|
CP0424261
|
N-(2-methylpropyl)-4-[(1-methylsulfonylpiperidin-4-yl)amino]-N-[2-(trifluoromethyl)phenyl]benzenesulfonamide
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|
C23H30F3N3O4S2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0424262
|
N-(2-methylpropyl)-5-(1-methylsulfonylpiperidin-4-yl)oxy-N-[[2-(trifluoromethyl)phenyl]methyl]pyridine-2-sulfonamide
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|
C23H30F3N3O5S2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0424263
|
N-(4-fluorophenyl)-N-(2-methylpropyl)-4-(1-methylsulfonylpiperidin-4-yl)oxybenzenesulfonamide
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|
C22H29FN2O5S2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0424264
|
N-(4-cyanophenyl)-N-(2-methylpropyl)-4-(1-methylsulfonylpiperidin-4-yl)oxybenzenesulfonamide
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|
C23H29N3O5S2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0424265
|
N-(2-methylpropyl)-4-[(1-methylsulfonylpiperidin-4-yl)amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzenesulfonamide
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|
C24H32F3N3O4S2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0052231
|
N-[[4-(4-acetylpiperazin-1-yl)phenyl]methyl]-N-cyclobutyl-1-phenylmethanesulfonamide
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|
C24H31N3O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0253451
|
N-[[4-(4-acetylpiperazin-1-yl)phenyl]methyl]-N-(2-methylpropyl)-1-phenylmethanesulfonamide
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|
C24H33N3O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0266018
|
N-[[4-(4-acetylpiperazin-1-yl)phenyl]methyl]-1-phenyl-N-(2,2,2-trifluoroethyl)methanesulfonamide
Show/Hide
|
C22H26F3N3O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0325717
|
N-[[4-(4-acetylpiperazin-1-yl)phenyl]methyl]-1-phenyl-N-propan-2-ylmethanesulfonamide
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|
C23H31N3O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0045770
|
4-[3-[2-chloro-6-(trifluoromethyl)benzoyl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-1-yl]-3-fluorobenzoic acid
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|
C22H15ClF4N2O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0059270
|
4-[3-[2-chloro-6-(trifluoromethyl)benzoyl]imidazo[1,5-a]pyridin-1-yl]-2-hydroxybenzoic acid
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|
C22H12ClF3N2O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0109853
|
4-[3-(2-chloro-6-cyclopropylbenzoyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-1-yl]-3-fluorobenzoic acid
Show/Hide
|
C24H20ClFN2O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0258549
|
4-[6-(2-chloro-6-cyclopropylbenzoyl)imidazo[1,5-a]pyrimidin-8-yl]-2-hydroxybenzoic acid
Show/Hide
|
C23H16ClN3O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0385839
|
4-[3-[2-chloro-6-(trifluoromethyl)benzoyl]imidazo[1,5-a]pyridin-1-yl]benzoic acid
Show/Hide
|
C22H12ClF3N2O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0385849
|
4-[3-[2-chloro-6-(trifluoromethyl)benzoyl]imidazo[1,5-a]pyridin-1-yl]-3-fluorobenzoic acid
Show/Hide
|
C22H11ClF4N2O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0450821
|
ethyl 5-[[[4-(3-methylsulfonylphenyl)phenyl]methyl-(2,4,6-trimethylphenyl)sulfonylamino]methyl]furan-2-carboxylate
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|
C31H33NO7S2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0272352
|
tert-butyl (2'R,3R)-1-[3-[4-(hydroxymethyl)-3-methylsulfonylphenyl]phenyl]-2-oxo-2'-propan-2-ylspiro[indole-3,3'-pyrrolidine]-1'-carboxylate
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|
C33H38N2O6S
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
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CP0418713
|
4-[3-[(2'S,3S)-1'-(tert-butylcarbamothioyl)-2-oxo-2'-propan-2-ylspiro[indole-3,3'-pyrrolidine]-1-yl]phenyl]-2-chloro-N,N-dimethylbenzamide
Show/Hide
|
C34H39ClN4O2S
|
1
|
| 1 |
IC50 = 1430 nM
|
|
|
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CP0478964
|
(2'S,3S)-1'-(3,3-dimethylbutanoyl)-1-[3-[4-(hydroxymethyl)-3-methylsulfonylphenyl]phenyl]-2'-propan-2-ylspiro[indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C34H40N2O5S
|
1
|
| 1 |
IC50 = 1790 nM
|
|
|
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CP0494689
|
(2'S,3S)-1'-(2,2-dimethylpropanoyl)-1-[3-[4-(hydroxymethyl)-3-methylsulfonylphenyl]phenyl]-2'-propan-2-ylspiro[indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C33H38N2O5S
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
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CP0549640
|
(2'S,3S)-1-[3-[4-(hydroxymethyl)-3-methylsulfonylphenyl]phenyl]-2'-propan-2-yl-1'-(2,2,2-trifluoroacetyl)spiro[indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C30H29F3N2O5S
|
1
|
| 1 |
IC50 = 3440 nM
|
|
|
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CP0478963
|
2-chloro-N,N-dimethyl-4-[3-[(2'S,3S)-2-oxo-2'-propan-2-yl-1'-propan-2-ylsulfonylspiro[indole-3,3'-pyrrolidine]-1-yl]phenyl]benzamide
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|
C32H36ClN3O4S
|
1
|
| 1 |
IC50 = 4570 nM
|
|
|
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CP0494690
|
tert-butyl (2'S,3S)-1-[3-[3-chloro-4-(hydroxymethyl)phenyl]phenyl]-2-oxo-2'-propan-2-ylspiro[indole-3,3'-pyrrolidine]-1'-carboxylate
Show/Hide
|
C32H35ClN2O4
|
1
|
| 1 |
IC50 = 6970 nM
|
|
|
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CP0465628
|
tert-butyl (2'S,3S)-1-[3-[4-(hydroxymethyl)phenyl]phenyl]-2-oxo-2'-propan-2-ylspiro[indole-3,3'-pyrrolidine]-1'-carboxylate
Show/Hide
|
C32H36N2O4
|
1
|
| 1 |
IC50 = 8640 nM
|
|
|
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CP0494671
|
4-[3-[(2'S,3S)-1'-[(2-methylpropan-2-yl)oxycarbonyl]-2-oxo-2'-propan-2-ylspiro[indole-3,3'-pyrrolidine]-1-yl]phenyl]-2-methylsulfonylbenzoic acid
Show/Hide
|
C33H36N2O7S
|
1
|
| 1 |
IC50 = 10080 nM
|
|
|
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CP0494672
|
tert-butyl (2'S,3S)-1-[3-(1-methylindol-6-yl)phenyl]-2-oxo-2'-propan-2-ylspiro[indole-3,3'-pyrrolidine]-1'-carboxylate
Show/Hide
|
C34H37N3O3
|
1
|
| 1 |
IC50 > 20000 nM
|
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