Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2'S,3S)-1-[3-[4-(hydroxymethyl)-3-methylsulfonylphenyl]phenyl]-2'-propan-2-yl-1'-(2,2,2-trifluoroacetyl)spiro[indole-3,3'-pyrrolidine]-2-one
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Canonical SMILES
CC(C)[C@@H]1N(CC[C@@]11C(=O)N(c2ccccc12)c1cccc(c1)-c1ccc(CO)c(c1)S(C)(=O)=O)C(=O)C(F)(F)F
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Compound Formula C30H29F3N2O5S
Compound Structure
Protein Name
 Protein Info 
Oxysterols receptor LXR-beta
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
P55055
Gene Name
NR1H2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3440 nM
   TI
   LI
   LO
   TS