| Compound ID |
Compound Name |
Compound Formula |
|
CP0382546
|
2-anilino-7-[(1S)-4-hydroxy-2,3-dihydro-1H-inden-1-yl]-5,5-dimethylpyrrolo[2,3-d]pyrimidin-6-one
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|
C23H22N4O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0060100
|
N-[(1S)-1-(2-anilino-5,5-dimethyl-6-oxopyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydro-1H-inden-4-yl]methanesulfonamide
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|
C24H25N5O3S
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0382544
|
7-[(1S)-1-(3-hydroxyphenyl)ethyl]-5,5-dimethyl-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one
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|
C21H21N5O2
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0307932
|
7-[(1S)-4-amino-2,3-dihydro-1H-inden-1-yl]-2-anilino-5,5-dimethylpyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
|
C23H23N5O
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0323244
|
7-[(1S)-2,3-dihydro-1H-inden-1-yl]-5,5-dimethyl-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
|
C22H21N5O
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0366861
|
7-cyclohexyl-5,5-dimethyl-2-(3-piperazin-1-ylanilino)pyrrolo[2,3-d]pyrimidin-6-one
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|
C24H32N6O
|
1
|
| 1 |
IC50 = 920 nM
|
|
|
|
CP0191016
|
5,5-dimethyl-7-[(1S)-1-phenylethyl]-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one
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|
C21H21N5O
|
1
|
| 1 |
IC50 = 2750 nM
|
|
|
|
CP0382542
|
5,5-dimethyl-7-(2-phenylpropan-2-yl)-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one
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|
C22H23N5O
|
1
|
| 1 |
IC50 = 3760 nM
|
|
|
|
CP0228585
|
7-[(2R)-butan-2-yl]-5,5-dimethyl-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one
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|
C17H21N5O
|
1
|
| 1 |
IC50 = 5910 nM
|
|
|
|
CP0307950
|
7-cyclohexyl-5,5-dimethyl-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one
Show/Hide
|
C19H23N5O
|
1
|
| 1 |
IC50 = 5990 nM
|
|
|
|
CP0267285
|
2-anilino-7-cyclohexyl-5,5-dimethylpyrrolo[2,3-d]pyrimidin-6-one
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|
C20H24N4O
|
1
|
| 1 |
IC50 = 8600 nM
|
|
|
|
CP0180469
|
2-anilino-7-[(1R)-2,2-difluoro-1-phenylethyl]-5,5-dimethylpyrrolo[2,3-d]pyrimidin-6-one
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|
C22H20F2N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0202678
|
2-anilino-5,5-dimethyl-7-phenylpyrrolo[2,3-d]pyrimidin-6-one
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|
C20H18N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0228586
|
2-anilino-5,5-dimethyl-6-(1-methylpyrazol-4-yl)pyrrolo[3,4-d]pyrimidin-7-one
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|
C18H18N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0254997
|
7-cyclohexyl-5,5-dimethyl-N-phenyl-6H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C20H26N4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0302978
|
7-[(1S)-1-(4-fluorophenyl)ethyl]-5,5-dimethyl-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one
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|
C21H20FN5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0307949
|
2-anilino-5,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-6-one
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|
C14H14N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0382541
|
2-anilino-5,5-dimethyl-7-[(2S)-3-methylbutan-2-yl]pyrrolo[2,3-d]pyrimidin-6-one
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|
C19H24N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
