Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT01212 , Serine/threonine-protein kinase 17A
Gene Name STK17A
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID Q9UEE5
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025  Protein ID: PT01212
 
Compound ID Compound Name Compound Formula
CP0004106
(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one
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C28H26N4O3
 1
1
IC50 = 54 nM
   TI
   LI
   LO
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CP0578527
N-[(1S)-1-pyridin-4-ylethyl]-7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxamide
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C24H24N6O3
 1
1
IC50 = 70 nM
   TI
   LI
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CP0579551
N-(1-phenylethyl)-7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxamide
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C25H25N5O3
 1
1
IC50 = 71 nM
   TI
   LI
   LO
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CP0569783
N-benzyl-7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxamide
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C24H23N5O3
 1
1
IC50 = 171 nM
   TI
   LI
   LO
   TS
CP0568288
N-tert-butyl-7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxamide
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C21H25N5O3
 1
1
IC50 = 182 nM
   TI
   LI
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CP0576027
7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaen-5-yl(morpholin-4-yl)methanone
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C21H23N5O4
 1
1
IC50 > 45000 nM
   TI
   LI
   LO
   TS
CP0579384
7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaen-5-yl-(4-methylpiperazin-1-yl)methanone
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C22H26N6O3
 1
1
IC50 > 45000 nM
   TI
   LI
   LO
   TS