Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
 Cell Line Info 
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT01060 , Serine/threonine-protein kinase D3
 Protein Info 
Gene Name PRKD3
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID O94806
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025
 Cell Line Info 
 Protein ID: PT01060
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0533915
 Compound Info 
2-[4-[[(2R)-2-aminobutyl]amino]pyrimidin-2-yl]-4-(1-methylpyrazol-4-yl)phenol
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C18H22N6O
  1
1
IC50 = 6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0485198
 Compound Info 
3-(1H-indol-3-yl)-1-(piperidin-4-ylmethyl)pyrazolo[3,4-d]pyrimidin-4-amine
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C19H21N7
  1
1
IC50 = 17 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0926275
 Compound Info 
3-(2-Ethoxyquinolin-6-yl)-1-((1-methylpiperidin-4-yl)-methyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
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C23H27N7O
  1
1
IC50 = 43 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0533913
 Compound Info 
3-[4-amino-3-(1H-indol-3-yl)pyrazolo[3,4-d]pyrimidin-1-yl]-2,2-dimethylpropan-1-ol
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C18H20N6O
  1
1
IC50 = 76 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0472472
 Compound Info 
3-naphthalen-1-yl-1-(piperidin-4-ylmethyl)pyrazolo[3,4-d]pyrimidin-4-amine
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C21H22N6
  1
1
IC50 = 78 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0472473
 Compound Info 
1-tert-butyl-3-(1H-indol-3-yl)pyrazolo[3,4-d]pyrimidin-4-amine
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C17H18N6
  1
1
IC50 = 108 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0533914
 Compound Info 
1-tert-butyl-3-(1H-pyrrolo[3,2-b]pyridin-3-yl)pyrazolo[3,4-d]pyrimidin-4-amine
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C16H17N7
  1
1
IC50 = 456 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0016790
 Compound Info 
1-tert-butyl-3-(naphthalen-1-ylmethyl)pyrazolo[3,4-d]pyrimidin-4-amine
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C20H21N5
  1
1
IC50 = 616 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0485196
 Compound Info 
1-tert-butyl-3-(1-methylindol-3-yl)pyrazolo[3,4-d]pyrimidin-4-amine
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C18H20N6
  1
1
IC50 = 4055 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS