Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT00967 , Glucocorticoid receptor
Gene Name NR3C1
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P04150
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025  Protein ID: PT00967
 
Compound ID Compound Name Compound Formula
CP0157489
Lmb763
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C27H22ClN3O4
 1
1
EC50 > 10000 nM
   TI
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   TS
CP0416614
1-[(1S,2R,13S,14S,17R,18S,20S)-17,20-dihydroxy-2,18-dimethyl-7-phenyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-hydroxyethanone
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C28H34N2O4
 1
1
Kd = 2.2 nM
   TI
   LI
   LO
   TS
CP0532961
1-[(1S,2R,13S,14S,17R,18S,20S)-17,20-dihydroxy-2,18-dimethyl-6-phenyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4,7,9-trien-17-yl]-2-hydroxyethanone
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C28H34N2O4
 1
1
Kd = 2.2 nM
   TI
   LI
   LO
   TS
CP0416607
1-[(1S,2R,13S,14S,17R,18S,20S)-7-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-hydroxyethanone
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C28H33FN2O4
 1
1
Kd = 2.6 nM
   TI
   LI
   LO
   TS
CP0008077
(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
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C22H29FO5
 1
1
Kd = 2.8 nM
   TI
   LI
   LO
   TS
CP0554235
1-[(1S,2R,13S,14S,17R,18S,20S)-7-hexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-hydroxyethanone
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C28H42N2O4
 1
1
Kd = 9 nM
   TI
   LI
   LO
   TS
CP0047927
3en3hg4wsw
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C21H26O5
 1
1
Kd = 29 nM
   TI
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CP0492126
1-[(1S,2R,13S,14S,17R,18S,20S)-17,20-dihydroxy-7-(3-methoxyphenyl)-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-hydroxyethanone
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C29H36N2O5
 1
1
Kd = 32 nM
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CP0542597
1-[(1S,2R,13S,14S,17R,18S,20S)-6-(4-fluorophenyl)-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4,7,9-trien-17-yl]-2-hydroxyethanone
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C28H33FN2O4
 1
1
Kd = 138 nM
   TI
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CP0554234
1-[(1S,2R,13S,14S,17R,18S,20S)-17,20-dihydroxy-2,18-dimethyl-6-(4-methylphenyl)-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4,7,9-trien-17-yl]-2-hydroxyethanone
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C29H36N2O4
 1
1
Kd = 883 nM
   TI
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   TS